Integration of phosphoproteomic, chemical, and biological strategies for the functional analysis of targeted protein phosphorylation (Q38057720)

27 August 2017

title

Integration of phosphoproteomic, chemical, and biological strategies for the functional analysis of targeted protein phosphorylation (English)

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27 August 2017

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Mingquan Guo

1

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27 August 2017

Bill X Huang

series ordinal

2

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27 August 2017

publication date

2 January 2013

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27 August 2017

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27 August 2017

volume

13

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27 August 2017

issue

3-4

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27 August 2017

page(s)

424-437

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Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Kinome signaling through regulated protein-protein interactions in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

The origins of protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteomics toolbox: computational biology, protein chemistry and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteomics strategies for the functional analysis of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Mechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Protein tyrosine kinases Src and Csk: a tail's tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphorylation in protein-protein binding: effect on stability and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Nuclear localization signal and phosphorylation of Serine350 specify intracellular localization of DRAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphorylation by casein kinase 2 regulates Nap1 localization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteomics, oncogenic signaling and cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Protein kinases--the major drug targets of the twenty-first century?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Targeting prostate cancer based on signal transduction and cell cycle pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

The promise of molecular targeted therapies: protein kinase inhibitors in the treatment of cutaneous malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Detection and analysis of protein histidine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Identification of histidine phosphorylations in proteins using mass spectrometry and affinity-based techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Mass spectrometry detection of histidine phosphorylation on NM23-H1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteomics for the discovery of kinases as cancer biomarkers and drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Functional organization of the S. cerevisiae phosphorylation network

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A novel proteomic screen for peptide-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Global and site-specific quantitative phosphoproteomics: principles and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative phosphoproteomics by mass spectrometry: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative phosphoproteomic analysis of signaling network dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative analysis of cell signaling and drug action via mass spectrometry-based systems level phosphoproteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteomics in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Crystal structure of an inactive Akt2 kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Interdomain conformational changes in Akt activation revealed by chemical cross-linking and tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Global analysis of protein phosphorylation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Kinomics: methods for deciphering the kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Peptide arrays: from macro to micro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A rapid method for determining protein kinase phosphorylation specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Structural basis and prediction of substrate specificity in protein serine/threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Identification of cGMP-dependent protein kinase and its specific substrates in the anterior pituitary

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A semisynthetic epitope for kinase substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Identification of CDK2 substrates in human cell lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Combining chemical genetics and proteomics to identify protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Switching the flip: protein phosphatase roles in signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Yeast substrate-trapping system for isolating substrates of protein tyrosine phosphatases: Isolation of substrates for protein tyrosine phosphatase receptor type z.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Tyrosine phosphoproteomics and identification of substrates of protein tyrosine phosphatase dPTP61F in Drosophila S2 cells by mass spectrometry-based substrate trapping strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Proteomic approaches to studying protein tyrosine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Novel Ser/Thr protein phosphatase 5 (PP5) regulated targets during DNA damage identified by proteomics analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Probing protein phosphatase substrate binding: affinity pull-down of ILKAP phosphatase 2C with phosphopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Detecting phosphorylation-dependent interactions with the C-terminal domain of RNA polymerase II subunit Rpb1p using a yeast two-hybrid assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

A novel quantitative proteomics strategy to study phosphorylation-dependent peptide-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEV

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Functional phosphosite screening for targeted protein-protein interactions by combining phosphoproteomics strategies and mammalian two-hybrid assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphotyrosine interactome of the ErbB-receptor kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Plk1 activation by Ste20-like kinase (Slk) phosphorylation and polo-box phosphopeptide binding assayed with the substrate translationally controlled tumor protein (TCTP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Systematic Discovery of In Vivo Phosphorylation Networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

NetworKIN: a resource for exploring cellular phosphorylation networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Targeted functional analysis of p300 coactivator in Wnt/β-catenin signaling pathway using phosphoproteomic and biochemical approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Distinct patterns of activation-dependent changes in conformational mobility between ERK1 and ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphorylation-induced conformational changes in Rap1b: allosteric effects on switch domains and effector loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Conformational changes in Akt1 activation probed by amide hydrogen/deuterium exchange and nano-electrospray ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Phosphatidylserine is a critical modulator for Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Probing Akt-inhibitor interaction by chemical cross-linking and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Effects of ethanol on conformational changes of Akt studied by chemical cross-linking, mass spectrometry, and (18)O labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative chemical proteomics approach to identify post-translational modification-mediated protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Chemical approaches towards unravelling kinase-mediated signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Quantitative proteomics for drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

Dasatinib: an anti-tumour agent via Src inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201200274

21 January 2018

Identifiers

DOI

10.1002/PMIC.201200274

1 reference

27 August 2017

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