Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record (Q38058157)

27 August 2017

Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record (English)

1 reference

27 August 2017

Peter M Jones

1

1 reference

PubMed ID

23131203

27 August 2017

Anthony M George

series ordinal

2

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27 August 2017

6 November 2012

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Critical Reviews in Biochemistry and Molecular Biology

27 August 2017

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27 August 2017

48

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27 August 2017

1

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27 August 2017

39-50

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Mg2+ -dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2).

27 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The maltose ATP-binding cassette transporter in the 21st century--towards a structural dynamic perspective on its mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Characterization of the Walker A motif of MsbA using site-directed spin labeling electron paramagnetic resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Characterization of the LSGGQ and H motifs from the Escherichia coli lipid A transporter MsbA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

A Tweezers-like Motion of the ATP-Binding Cassette Dimer in an ABC Transport Cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure, function, and evolution of bacterial ATP-binding cassette systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure of a bacterial multidrug ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

ABC efflux pump-based resistance to chemotherapy drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Multidrug efflux pumps: substrate selection in ATP-binding cassette multidrug efflux pumps--first come, first served?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

A comparative electron paramagnetic resonance study of the nucleotide-binding domains' catalytic cycle in the assembled maltose ATP-binding cassette importer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Transmembrane signaling in the maltose ABC transporter MalFGK2-E: periplasmic MalF-P2 loop communicates substrate availability to the ATP-bound MalK dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Lipid composition regulates the orientation of transmembrane helices in HorA, an ABC multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Dimerization of ABCG2 analysed by bimolecular fluorescence complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The ATP switch model for ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure and mechanism of ABC transporter proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure of an ABC transporter in complex with its binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Nucleotide Dependent Monomer/Dimer Equilibrium of OpuAA, the Nucleotide-binding Protein of the Osmotically Regulated ABC Transporter OpuA from Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Monitoring conformational changes during the catalytic cycle of OpuAA, the ATPase subunit of the ABC transporter OpuA from Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Crystal structure of the ATP-binding subunit of an ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Subunit interactions in ABC transporters: towards a functional architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The ABC transporter structure and mechanism: perspectives on recent research.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Opening of the ADP-bound active site in the ABC transporter ATPase dimer: evidence for a constant contact, alternating sites model for the catalytic cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Molecular-dynamics simulations of the ATP/apo state of a multidrug ATP-binding cassette transporter provide a structural and mechanistic basis for the asymmetric occluded state

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

ABC transporters: a riddle wrapped in a mystery inside an enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Alternating Access in Maltose Transporter Mediated by Rigid-Body Rotations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The ATP-binding cassette family: a structural perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Thermodynamics and dynamics of histidine-binding protein, the water-soluble receptor of histidine permease. Implications for the transport of high and low affinity ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Structural arrangement of the transmission interface in the antigen ABC transport complex TAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Crystal structure of the maltose transporter in a pretranslocation intermediate state

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Dynamics of alpha-helical subdomain rotation in the intact maltose ATP-binding cassette transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Catalytic cycle of ATP hydrolysis by P-glycoprotein: evidence for formation of the E.S reaction intermediate with ATP-gamma-S, a nonhydrolyzable analogue of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Characterization of an asymmetric occluded state of P-glycoprotein with two bound nucleotides: implications for catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Time-resolved Fourier transform infrared spectroscopy of the nucleotide-binding domain from the ATP-binding Cassette transporter MsbA: ATP hydrolysis is the rate-limiting step in the catalytic cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gating

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

State-dependent modulation of CFTR gating by pyrophosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

ABC transporters: one, two or four extracytoplasmic substrate-binding sites?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Dynamic ligand-induced conformational rearrangements in P-glycoprotein as probed by fluorescence resonance energy transfer spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Characterization of site-directed mutations in conserved domains of MalK, a bacterial member of the ATP-binding cassette (ABC) family [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Kinetics of the Association/Dissociation Cycle of an ATP-binding Cassette Nucleotide-binding Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Conformational cycle of the ABC transporter MsbA in liposomes: detailed analysis using double electron-electron resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

Alternating access of the putative substrate-binding chamber in the ABC transporter MsbA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735644

10.3109/10409238.2012.735644

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

23131203