The PGC-1/ERR signaling axis in cancer (Q38064784)

28 August 2017

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title

The PGC-1/ERR signaling axis in cancer (English)

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28 August 2017

3

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28 August 2017

G Deblois

1

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28 August 2017

J St-Pierre

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

3 December 2012

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28 August 2017

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28 August 2017

32

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28 August 2017

30

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28 August 2017

3483-3490

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https://scigraph.springernature.com/pub.10.1038/onc.2012.529

28 August 2017

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cites work

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

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https://api.crossref.org/works/10.1038%2FONC.2012.529

Tumor suppressors and cell metabolism: a recipe for cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Transcriptional control of energy homeostasis by the estrogen-related receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Transcriptional control of mitochondrial biogenesis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

ERRs and cancers: effects on metabolism and on proliferation and migration capacities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Identification of a new class of steroid hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

ERRalpha: a metabolic function for the oldest orphan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Nuclear receptor expression links the circadian clock to metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Intra-tumour heterogeneity: a looking glass for cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Targeting cancer metabolism: a therapeutic window opens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.529

Cells silenced for SDHB expression display characteristic features of the tumor phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Transcriptional control of the ERBB2 amplicon by ERRalpha and PGC-1beta promotes mammary gland tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Links between metabolism and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Therapeutic targets in cancer cell metabolism and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Mitochondria and reactive oxygen species in renal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Adaptation of energy metabolism in breast cancer brain metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Epidermal growth factor-induced signaling in breast cancer cells results in selective target gene activation by orphan nuclear receptor estrogen-related receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Myc and mammary cancer: Myc is a downstream effector of the ErbB2 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

HER2 signaling enhances 5'UTR-mediated translation of c-Myc mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Expression of estrogen-receptor related receptors in amphioxus and zebrafish: implications for the evolution of posterior brain segmentation at the invertebrate-to-vertebrate transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic Ras-dependent anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The significance of the expression of ERRalpha as a potential biomarker in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Expression of estrogen receptor-related receptor isoforms and clinical significance in endometrial adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Differential expression of estrogen-related receptors beta and gamma (ERRbeta and ERRgamma) and their clinical significance in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Oestrogen receptor-related receptor alpha (ERRalpha) and oestrogen receptors (ERalpha and ERbeta) exhibit different gene expression in human colorectal tumour progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The PGC-1alpha-dependent pathway of mitochondrial biogenesis is upregulated in type I endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

The NR3B subgroup: an ovERRview

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Expression of the orphan nuclear receptor ERRalpha is under circadian regulation in estrogen-responsive tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Expression of peroxisome-proliferator activated receptor-gamma (PPAR?) and the PPAR? co-activator, PGC-1, in human breast cancer correlates with clinical outcomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

Clinical implication of estrogen-related receptor (ERR) expression in ovarian cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.529

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.529

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Dimensions Publication ID

28 August 2017

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