Gene mutations of acute myeloid leukemia in the genome era. (Q38077505)

28 August 2017

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title

Gene mutations of acute myeloid leukemia in the genome era. (English)

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28 August 2017

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acute myeloid leukemia

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Tomoki Naoe

1

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28 August 2017

Hitoshi Kiyoi

series ordinal

2

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28 August 2017

publication date

29 January 2013

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International Journal of Hematology

28 August 2017

published in

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28 August 2017

volume

97

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28 August 2017

issue

2

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28 August 2017

page(s)

165-174

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Dysregulation of the C/EBPalpha differentiation pathway in human cancer

28 August 2017

cites work

1 reference

12 December 2020

Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes

1 reference

12 December 2020

IDH mutations in glioma and acute myeloid leukemia

1 reference

12 December 2020

DNMT3A Mutations in Acute Myeloid Leukemia

1 reference

12 December 2020

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

1 reference

12 December 2020

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases

1 reference

12 December 2020

SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

1 reference

12 December 2020

Deregulated transcription factors in leukemia

1 reference

12 December 2020

Acute myeloid leukaemia

1 reference

12 December 2020

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

1 reference

12 December 2020

The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes

1 reference

12 December 2020

Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study

1 reference

12 December 2020

N-ras mutations in adult de novo acute myelogenous leukemia: prevalence and clinical significance.

1 reference

12 December 2020

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

1 reference

12 December 2020

Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

1 reference

12 December 2020

Clinical effect of point mutations in myelodysplastic syndromes

1 reference

12 December 2020

The Polycomb complex PRC2 and its mark in life

1 reference

12 December 2020

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

1 reference

12 December 2020

The role of mutations in epigenetic regulators in myeloid malignancies

1 reference

12 December 2020

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

1 reference

12 December 2020

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor

1 reference

12 December 2020

Acquired mutations in TET2 are common in myelodysplastic syndromes

1 reference

12 December 2020

Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing

1 reference

12 December 2020

CTCF, cohesin, and histone variants: connecting the genome

1 reference

12 December 2020

Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications

1 reference

12 December 2020

The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse

1 reference

12 December 2020

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

1 reference

12 December 2020

Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia.

1 reference

12 December 2020

Cohesin ties up the genome

1 reference

12 December 2020

Core-binding factors in haematopoiesis and leukaemia

1 reference

12 December 2020

Mutation in TET2 in myeloid cancers

1 reference

12 December 2020

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

1 reference

12 December 2020

Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia

1 reference

12 December 2020

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia

1 reference

12 December 2020

Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms

1 reference

12 December 2020

TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study

1 reference

12 December 2020

The DNMT3 family of mammalian de novo DNA methyltransferases

1 reference

12 December 2020

Clonal architecture of secondary acute myeloid leukemia

1 reference

12 December 2020

Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

1 reference

12 December 2020

The origin and evolution of mutations in acute myeloid leukemia

1 reference

12 December 2020

Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples

1 reference

12 December 2020

Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias

1 reference

12 December 2020

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia

1 reference

12 December 2020

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

1 reference

12 December 2020

PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

1 reference

12 December 2020

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

1 reference

12 December 2020

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

1 reference

12 December 2020

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

1 reference

12 December 2020

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

1 reference

12 December 2020

Genetics of myeloid malignancies: pathogenetic and clinical implications

1 reference

12 December 2020

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

1 reference

12 December 2020

Recurring mutations found by sequencing an acute myeloid leukemia genome

1 reference

12 December 2020

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

1 reference

12 December 2020

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

1 reference

12 December 2020

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

1 reference

12 December 2020

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

1 reference

12 December 2020

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.

1 reference

12 December 2020

The role of FLT3 in haematopoietic malignancies

1 reference

12 December 2020

C-kit mutations in core binding factor leukemias

1 reference

12 December 2020

Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

1 reference

12 December 2020

Dnmt3a is essential for hematopoietic stem cell differentiation

1 reference

12 December 2020

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.

1 reference

12 December 2020

Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia

1 reference

12 December 2020

TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group

1 reference

12 December 2020

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

12 December 2020

Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia

1 reference

12 December 2020

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

1 reference

12 December 2020

High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine

1 reference

12 December 2020

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression

1 reference

12 December 2020

FLT3 in human hematologic malignancies

1 reference

12 December 2020

AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

1 reference

12 December 2020

Biology, clinical relevance, and molecularly targeted therapy in acute leukemia with FLT3 mutation

1 reference

12 December 2020

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

1 reference

12 December 2020

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.

1 reference

12 December 2020

Core binding factor acute myeloid leukemia

1 reference

12 December 2020

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

1 reference

12 December 2020

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

1 reference

12 December 2020

Splicing factor mutations in myelodysplasia

1 reference

12 December 2020

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

1 reference

12 December 2020

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

1 reference

12 December 2020

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

1 reference

12 December 2020

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

1 reference

12 December 2020

Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia

1 reference

12 December 2020

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

1 reference

12 December 2020

Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene.

1 reference

12 December 2020

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia.

1 reference

12 December 2020

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

1 reference

12 December 2020

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes.

1 reference

12 December 2020

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

1 reference

12 December 2020

The 8;21 translocation in leukemogenesis

1 reference

12 December 2020

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

1 reference

12 December 2020

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

1 reference

12 December 2020

A novel hierarchical prognostic model of AML solely based on molecular mutations

1 reference

12 December 2020

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

12 December 2020

10.1007/S12185-013-1257-4

Identifiers

DOI

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Dimensions Publication ID

28 August 2017

1042211114

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