Sensing hypoxia: physiology, genetics and epigenetics (Q38086431)

28 August 2017

Sensing hypoxia: physiology, genetics and epigenetics (English)

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28 August 2017

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Nanduri R Prabhakar

1

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PubMed ID

23459758

28 August 2017

language of work or name

English

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publication date

4 March 2013

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28 August 2017

13

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inferred from page(s)

published in

Journal of Physiology

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28 August 2017

591

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28 August 2017

2245-2257

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28 August 2017

9

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Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat.

28 August 2017

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

A possible dual site of action for carbon monoxide-mediated chemoexcitation in the rat carotid body.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Reciprocal regulation of Rac1 and PAK-1 by HIF-1alpha: a positive-feedback loop promoting pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hydrogen sulfide mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Ion channel regulation by the LKB1-AMPK signalling pathway: the key to carotid body activation by hypoxia and metabolic homeostasis at the whole body level

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Phenotypic plasticity and the epigenetics of human disease

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The impact of hydrogen sulfide (H₂S) on neurotransmitter release from the cat carotid body.

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hydrogen sulfide as a gasotransmitter

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

CpG islands in vertebrate genomes

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The fetal, neonatal, and infant environments-the long-term consequences for disease risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hypoxia-induced arterial chemoreceptor stimulation and hydrogen sulfide: too much or too little?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Signaling by sensory receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Chemoreflexes--physiology and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Oxygen sensing in the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The heme oxygenase system: a regulator of second messenger gases

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Endogenous H2S is required for hypoxic sensing by carotid body glomus cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The human carotid body transcriptome with focus on oxygen sensing and inflammation--a comparative analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Acute oxygen sensing in heme oxygenase-2 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

H2S mediates O2 sensing in the carotid body

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Endogenous carbon monoxide in control of respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

NO and CO as second messengers in oxygen sensing in the carotid body

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Carbon monoxide: a role in carotid body chemoreception

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

ROS signaling in systemic and cellular responses to chronic intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Sympatho-adrenal activation by chronic intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Contribution of endothelin-1 to the enhanced carotid body chemosensory responses induced by chronic intermittent hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

O(2) modulates large-conductance Ca(2+)-dependent K(+) channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Developmental changes in HIF transcription factor in carotid body: relevance for O2 sensing by chemoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Carotid body function in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Variation in human ventilatory control-genetic influence on the hypoxic ventilatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2012.247759

Peripheral chemoreceptors: function and plasticity of the carotid body

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Oxygen sensing during intermittent hypoxia: cellular and molecular mechanisms

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Invited review: Physiological consequences of intermittent hypoxia: systemic blood pressure

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Oxygen sensing by the carotid body chemoreceptors

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Ventilatory and pulmonary vascular response to hypoxia and susceptibility to high altitude pulmonary oedema

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Chemoreflexes--responses, interactions and implications for sleep apnea

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Carotid body chemoreceptors: from natural stimuli to sensory discharges

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Peripheral chemoreceptor reflex in obstructive sleep apnea patients; a relationship between ventilatory response to hypoxia and nocturnal bradycardia during apnea events

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Reactivity of the phosphopyridoxal groups of cystathionase

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650692

Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity

5 November 2018

1 reference

12 December 2020

The Oxygen and Carbon Monoxide Reactions of Heme Oxygenase

1 reference

12 December 2020

Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous system

1 reference

12 December 2020

Strain-associated differences in hypoxic chemosensitivity of the carotid body in rats

1 reference

12 December 2020

Abdominal vagal paraganglia: distribution and comparison with carotid body, in the rat

1 reference

12 December 2020

The distribution of thoracic glomus tissue (aortic bodies) in the rat

1 reference

12 December 2020

10.1113/JPHYSIOL.2012.247759

Identifiers

DOI

1 reference

28 August 2017

0 references

1 reference

PubMed ID

23459758