Reactive aldehydes--second messengers of free radicals in diabetes mellitus (Q38092186)

28 August 2017

Reactive aldehydes--second messengers of free radicals in diabetes mellitus (English)

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28 August 2017

M Jaganjac

1

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28 August 2017

O Tirosh

2

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28 August 2017

G Cohen

3

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28 August 2017

S Sasson

4

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28 August 2017

N Zarkovic

5

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28 August 2017

25 April 2013

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28 August 2017

Free Radical Research

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28 August 2017

47 Suppl 1

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28 August 2017

39-48

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Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.

28 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Novel aspects of the molecular mechanisms controlling insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Fatty acids and glucose in high concentration down-regulates ATP synthase beta-subunit protein expression in INS-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative stress: the vulnerable beta-cell

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Type 2 diabetes-a matter of beta-cell life and death?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative burst of neutrophils against melanoma B16-F10.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Even stressed cells are individuals: second messengers of free radicals in pathophysiology of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Two tales of antioxidant enzymes on β cells and diabetes

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Role of forkhead transcription factors in diabetes-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Forkhead homeobox type O transcription factors in the responses to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative stress and diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Advanced lipoxidation end-products.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Targeting NADPH oxidases in vascular pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products, important mediators of chronic complications of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Involvement of RAGE, NADPH oxidase, and Ras/Raf-1 pathway in glycated LDL-induced expression of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

HSP72 protects against obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

4-hydroxynonenal as a bioactive marker of pathophysiological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Cellular glutathione and thiols metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative stress and covalent modification of protein with bioactive aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Skeletal muscle lipid peroxidation and insulin resistance in humans

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Pathological aspects of lipid peroxidation.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Lipid peroxidation is not a prerequisite for the development of obesity and diabetes in high-fat-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Role of physiological levels of 4-hydroxynonenal on adipocyte biology: implications for obesity and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Mutual dependence of growth modifying effects of 4-hydroxynonenal and fetal calf serum in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Mitochondrial alterations in aging rat brain: effective role of (-)-epigallo catechin gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

A fish-oil-rich diet reduces vascular oxidative stress in apoE(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Natural and synthetic antioxidants: an updated overview

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

SOD1 suppresses maternal hyperglycemia-increased iNOS expression and consequent nitrosative stress in diabetic embryopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

PPARdelta regulates glucose metabolism and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Therapeutic modulators of peroxisome proliferator-activated receptors (PPAR): a patent review (2008-present).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Ligand- and structure-based drug design strategies and PPARδ/α selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Lipid peroxidation of poly-unsaturated fatty acids in normal and obese adipose tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Signaling and cytotoxic functions of 4-hydroxyalkenals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

L-carnosine, a substrate of carnosinase-1, influences glucose metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2013.789136

10.3109/10715762.2013.789136

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference