Biologic agents in osteoarthritis: hopes and disappointments (Q38094906)

28 August 2017

Biologic agents in osteoarthritis: hopes and disappointments (English)

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28 August 2017

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Xavier Chevalier

1

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28 August 2017

Florent Eymard

series ordinal

2

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28 August 2017

Pascal Richette

series ordinal

3

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28 August 2017

language of work or name

English

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publication date

2 April 2013

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Nature Reviews Rheumatology

28 August 2017

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28 August 2017

9

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28 August 2017

7

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28 August 2017

400-410

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2013.44

28 August 2017

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Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee.

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21 January 2018

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A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee

21 January 2018

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Recent advances in BMP receptor signaling

21 January 2018

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Overview of bone morphogenetic proteins

21 January 2018

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Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

21 January 2018

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The effect of growth factor treatment on meniscal chondrocyte proliferation and differentiation on polyglycolic acid scaffolds

21 January 2018

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Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors

21 January 2018

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FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

21 January 2018

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Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis

21 January 2018

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Osteophytes: relevance and biology

21 January 2018

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Pharmacologic therapy for osteoarthritis--the era of disease modification

21 January 2018

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The role of synovitis in osteoarthritis pathogenesis

21 January 2018

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Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms

21 January 2018

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The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

21 January 2018

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Are we moving in the right direction with osteoarthritis drug discovery?

21 January 2018

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Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate

21 January 2018

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The IL-6/sIL-6R complex as a novel target for therapeutic approaches

21 January 2018

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To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy

21 January 2018

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Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification

21 January 2018

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Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

21 January 2018

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The role of cytokines in cartilage matrix degeneration in osteoarthritis.

21 January 2018

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Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3

31 March 2020

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Nerve growth factor and pain

31 March 2020

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Nerve growth factor concentrations in the synovial fluid from healthy dogs and dogs with secondary osteoarthritis

31 March 2020

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Efficacy and safety of tanezumab in the treatment of chronic low back pain

31 March 2020

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Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression

31 March 2020

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Stress-induced cartilage degradation does not depend on the NLRP3 inflammasome in human osteoarthritis and mouse models

31 March 2020

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Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.44

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity

31 March 2020

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Clinical benefits of intra-articular anakinra for persistent knee effusion.

31 March 2020

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Efficacy of infliximab in a rabbit model of osteoarthritis

31 March 2020

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Osteoarthritis: best evidence for best therapies in hand osteoarthritis

31 March 2020

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Edema of the bone marrow can cause pain in osteoarthritis and other diseases of bone and joints

31 March 2020

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Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level

31 March 2020

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Osteogenic protein-1: biology and applications

31 March 2020

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12 December 2020

Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid

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Suppression of experimental osteoarthritis by adenovirus-mediated double gene transfer.

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JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical

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[Physiopathogenesis of osteoarthritis. The arthritis cartilage]

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12 December 2020

A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands

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12 December 2020

Intra-articular administration of interleukin-1 causes prolonged suppression of cartilage proteoglycan synthesis in rats

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12 December 2020

DMOAD developments: present and future

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12 December 2020

A high interleukin 1 receptor antagonist/IL-1beta ratio occurs naturally in knee osteoarthritis

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Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study

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[Targeted anti-cytokine therapies for osteoarthritis]

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2013.44

1 reference

Dimensions Publication ID

28 August 2017

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1 reference