The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism (Q38100770)

28 August 2017

The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism (English)

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28 August 2017

Ricardo Soto-Rifo

1

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PubMed ID

23606618

28 August 2017

Théophile Ohlmann

series ordinal

2

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28 August 2017

18 April 2013

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Wiley interdisciplinary reviews. RNA

28 August 2017

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28 August 2017

4

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28 August 2017

4

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28 August 2017

369-385

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The origins of the RNA world

28 August 2017

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The RNA worlds in context

21 January 2018

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How RNA unfolds and refolds

21 January 2018

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Functional coherence of the human Y chromosome

21 January 2018

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Assignment of a human putative RNA helicase gene, DDX3, to human X chromosome bands p11.3-->p11.23

21 January 2018

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Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility

21 January 2018

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From unwinding to clamping - the DEAD box RNA helicase family

21 January 2018

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21 January 2018

Birth of the D-E-A-D box

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Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function

21 January 2018

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Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity

21 January 2018

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Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP

21 January 2018

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RNA helicases at work: binding and rearranging

21 January 2018

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Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases

21 January 2018

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Toward a molecular understanding of RNA remodeling by DEAD-box proteins

21 January 2018

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DEAD-box proteins as RNA helicases and chaperones

21 January 2018

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Structure and mechanism of helicases and nucleic acid translocases

21 January 2018

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RNA helicases and remodeling proteins

21 January 2018

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Non-hexameric DNA helicases and translocases: mechanisms and regulation

21 January 2018

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Stepwise translocation of nucleic acid motors.

21 January 2018

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Translocation and unwinding mechanisms of RNA and DNA helicases

21 January 2018

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Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation

21 January 2018

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Viruses and the human DEAD-box helicase DDX3: inhibition or exploitation?

21 January 2018

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The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control

21 January 2018

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Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

21 January 2018

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DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

21 January 2018

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Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

21 January 2018

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The current understanding of Ded1p/DDX3 homologs from yeast to human

21 January 2018

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The DDX3 subfamily of the DEAD box helicases: divergent roles as unveiled by studying different organisms and in vitro assays

21 January 2018

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SF1 and SF2 helicases: family matters

21 January 2018

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The RNA helicase database

21 January 2018

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The DEAD-box protein family of RNA helicases

21 January 2018

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Discriminatory RNP remodeling by the DEAD-box protein DED1.

21 January 2018

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DEAD-box proteins unwind duplexes by local strand separation

21 January 2018

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ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

21 January 2018

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DEAD-box proteins can completely separate an RNA duplex using a single ATP.

21 January 2018

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The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA

21 January 2018

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The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity

21 January 2018

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Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

21 January 2018

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DExD/H box RNA helicases: from generic motors to specific dissociation functions

21 January 2018

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A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication

21 January 2018

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Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein

21 January 2018

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DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor

21 January 2018

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From birth to death: the complex lives of eukaryotic mRNAs

21 January 2018

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Pre-mRNA processing reaches back to transcription and ahead to translation

21 January 2018

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Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast

21 January 2018

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The eukaryotic transcriptional machinery regulates mRNA translation and decay in the cytoplasm

21 January 2018

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Pre-mRNA splicing: where and when in the nucleus

21 January 2018

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Human mRNA export machinery recruited to the 5' end of mRNA

21 January 2018

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Recruitment of the human TREX complex to mRNA during splicing

21 January 2018

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How introns influence and enhance eukaryotic gene expression

21 January 2018

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EJCs at the heart of translational control

21 January 2018

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Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

21 January 2018

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The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

21 January 2018

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Regulation by HIV Rev depends upon recognition of splice sites

21 January 2018

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The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

21 January 2018

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DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential

21 January 2018

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Oncogenic role of DDX3 in breast cancer biogenesis.

21 January 2018

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Comprehensive proteomic analysis of the human spliceosome

21 January 2018

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Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

21 January 2018

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Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

21 January 2018

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eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR

21 January 2018

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eIF4E is a central node of an RNA regulon that governs cellular proliferation

21 January 2018

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21 January 2018

THE HIV-1 REV PROTEIN

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Nuclear mRNA export: insights from virology

21 January 2018

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Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export

21 January 2018

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Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export

21 January 2018

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Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production

21 January 2018

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HIV-1 remodels the nuclear pore complex

21 January 2018

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Requirement of the DEAD-Box protein ded1p for messenger RNA translation

21 January 2018

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The p20 and Ded1 proteins have antagonistic roles in eIF4E-dependent translation in Saccharomyces cerevisiae.

21 January 2018

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Hepatitis C virus core protein binds to a DEAD box RNA helicase

21 January 2018

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The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

21 January 2018

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A temperature-sensitive mutant of the mammalian RNA helicase, DEAD-BOX X isoform, DBX, defective in the transition from G1 to S phase.

21 January 2018

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DDX3 regulates cell growth through translational control of cyclin E1

21 January 2018

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The DEAD-box RNA helicase Ded1p affects and accumulates in Saccharomyces cerevisiae P-bodies

21 January 2018

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The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex

21 January 2018

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Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning.

21 January 2018

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Unwinding single RNA molecules using helicases involved in eukaryotic translation initiation.

21 January 2018

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Dynamics and processivity of 40S ribosome scanning on mRNA in yeast

21 January 2018

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Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation.

21 January 2018

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21 January 2018

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RNA granules: post-transcriptional and epigenetic modulators of gene expression

21 January 2018

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mRNA localization: gene expression in the spatial dimension

21 January 2018

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Stress granules: the Tao of RNA triage

21 January 2018

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P bodies: at the crossroads of post-transcriptional pathways

21 January 2018

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Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

21 January 2018

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Characterization of an RNA granule from developing brain.

21 January 2018

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P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

21 January 2018

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Hepatitis C virus core protein interacts with a human DEAD box protein DDX3

21 January 2018

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Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

21 January 2018

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DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication

21 January 2018

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Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants

21 January 2018

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Hepatitis C virus core protein abrogates the DDX3 function that enhances IPS-1-mediated IFN-beta induction

21 January 2018

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Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion

21 January 2018

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Identification of RNA-protein interaction networks involved in the norovirus life cycle

21 January 2018

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Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.

21 January 2018

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Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

21 January 2018

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Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry

21 January 2018

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Phosphoproteomics for the discovery of kinases as cancer biomarkers and drug targets

21 January 2018

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A quantitative atlas of mitotic phosphorylation

21 January 2018

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The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export

21 January 2018

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Gene expression analysis in human breast cancer associated blood vessels

21 January 2018

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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

21 January 2018

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Novel mutations target distinct subgroups of medulloblastoma.

21 January 2018

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The mutational landscape of head and neck squamous cell carcinoma

21 January 2018

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Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer

21 January 2018

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SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

21 January 2018

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DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control

21 January 2018

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Toward the discovery of novel anti-HIV drugs. Second-generation inhibitors of the cellular ATPase DDX3 with improved anti-HIV activity: synthesis, structure-activity relationship analysis, cytotoxicity studies, and target validation.

21 January 2018

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The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WRNA.1165

1 reference

28 August 2017

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PubMed ID

23606618