Towards a new science of secondary metabolism (Q38101244)

28 August 2017

Towards a new science of secondary metabolism (English)

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28 August 2017

Arryn Craney

1

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28 August 2017

Salman Ahmed

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2

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28 August 2017

Justin Nodwell

series ordinal

3

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28 August 2017

24 April 2013

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The Journal of Antibiotics

28 August 2017

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28 August 2017

66

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28 August 2017

7

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28 August 2017

387-400

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https://scigraph.springernature.com/pub.10.1038/ja.2013.25

28 August 2017

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cites work

Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

How many antibiotics are produced by the genus Streptomyces?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Exploiting the genetic potential of polyketide producing streptomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Giant linear plasmids in Streptomyces: a treasure trove of antibiotic biosynthetic clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Renaissance in antibacterial discovery from actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Marine actinomycetes as an emerging resource for the drug development pipelines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

New antibiotics from bacterial natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Secondary metabolites of soil Bacillus spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Myxobacteria: proficient producers of novel natural products with various biological activities--past and future biotechnological aspects with the focus on the genus Sorangium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genomics of secondary metabolite production by Pseudomonas spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Discovery of antibacterials and other bioactive compounds from microorganisms-evaluating methodologies for discovery and generation of non-ribosomal peptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genomic basis for natural product biosynthetic diversity in the actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Signals and regulators that govern Streptomyces development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Actinorhodin is a chromosomally-determined antibiotic in Streptomyces coelicolar A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Chapter 7. Cloning and analysis of natural product pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Natural and synthetic tetracycline-inducible promoters for use in the antibiotic-producing bacteria Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

xylE functions as an efficient reporter gene in Streptomyces spp.: use for the study of galP1, a catabolite-controlled promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A connection between stress and development in the multicellular prokaryote Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A master regulator sigmaB governs osmotic and oxidative response as well as differentiation via a network of sigma factors in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Regulation of sporulation in Streptomyces coelicolor A3(2): a checkpoint multiplex?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Regulation of Streptomyces development: reach for the sky!

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Morphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Association of early sporulation genes with suggested developmental decision points in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The positions of the sigma-factor genes, whiG and sigF, in the hierarchy controlling the development of spore chains in the aerial hyphae of Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Biosynthesis of actinorhodin and related antibiotics: discovery of alternative routes for quinone formation encoded in the act gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Biosynthesis of bacterial aromatic polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The biosynthesis and regulation of bacterial prodiginines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Signalling early developmental events in two highly diverged Streptomyces species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Phosphorylation of the AfsR protein involved in secondary metabolism in Streptomyces species by a eukaryotic-type protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Autophosphorylation of a bacterial serine/threonine kinase, AfsK, is inhibited by KbpA, an AfsK-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Production of a novel polyketide antibiotic, jadomycin B, by Streptomyces venezuelae following heat shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Control of secondary metabolism by farX, which is involved in the gamma-butyrolactone biosynthesis of Streptomyces lavendulae FRI-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Deletion of scbA enhances antibiotic production in Streptomyces lividans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Strain improvement of Streptomyces roseosporus for daptomycin production by rational screening of He-Ne laser and NTG induced mutants and kinetic modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Culture conditions improving the production of jadomycin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Big effects from small changes: possible ways to explore nature's chemical diversity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Light-induced carotenogenesis in Streptomyces coelicolor A3(2): identification of an extracytoplasmic function sigma factor that directs photodependent transcription of the carotenoid biosynthesis gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The future of industrial antibiotic production: from random mutagenesis to synthetic biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Novel links between antibiotic resistance and antibiotic production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Phosphopantetheinyl transferase inhibition and secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Chemical perturbation of secondary metabolism demonstrates important links to primary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A synthetic, species-specific activator of secondary metabolism and sporulation in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Expression of the SalI restriction-modification system of Streptomyces albus G in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification of a methyl-specific restriction system mediated by a conjugative element from Streptomyces bambergiensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A two-step mechanism for the activation of actinorhodin export and resistance in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Exploration and mining of the bacterial terpenome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Structural insights into nonribosomal peptide enzymatic assembly lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Structure-based dissociation of a type I polyketide synthase module

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Towards prediction of metabolic products of polyketide synthases: an in silico analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A mass spectrometry-guided genome mining approach for natural product peptidogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Translating metabolic exchange with imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Cloning of genes involved in erythromycin biosynthesis from Saccharopolyspora erythraea using a novel actinomycete-Escherichia coli cosmid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Purification and structural determination of SCB1, a gamma-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Streptomyces coelicolor A3(2) produces a new yellow pigment associated with the polyketide synthase Cpk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Nucleotide sequence and transcriptional analysis of the redD locus of Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

bldA dependence of undecylprodigiosin production in Streptomyces coelicolor A3(2) involves a pathway-specific regulatory cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Regulation of a novel gene cluster involved in secondary metabolite production in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Biochemical activities of the absA two-component system of Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genetic and transcriptional analysis of absA, an antibiotic gene cluster-linked two-component system that regulates multiple antibiotics in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

AfsR as an integrator of signals that are sensed by multiple serine/threonine kinases in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Novel two-component systems implied in antibiotic production in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Two overlapping antiparallel genes encoding the iron regulator DmdR1 and the Adm proteins control siderophore [correction of sedephore] and antibiotic biosynthesis in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Characterization of a novel two-component regulatory system involved in the regulation of both actinorhodin and a type I polyketide in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The role of absC, a novel regulatory gene for secondary metabolism, in zinc-dependent antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

NdgR, an IclR-like regulator involved in amino-acid-dependent growth, quorum sensing, and antibiotic production in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Characterization of rrdA, a TetR family protein gene involved in the regulation of secondary metabolism in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification and characterization of CdgB, a diguanylate cyclase involved in developmental processes in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Identification of a gene negatively affecting antibiotic production and morphological differentiation in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

ssgA is essential for sporulation of Streptomyces coelicolor A3(2) and affects hyphal development by stimulating septum formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Transcription of the sporulation gene ssgA is activated by the IclR-type regulator SsgR in a whi-independent manner in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The use of the rare UUA codon to define "expression space" for genes involved in secondary metabolism, development and environmental adaptation in streptomyces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Regulation of morphological differentiation in S. coelicolor by RNase III (AbsB) cleavage of mRNA encoding the AdpA transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

The G243D mutation (afsB mutation) in the principal sigma factor sigmaHrdB alters intracellular ppGpp level and antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

EshA accentuates ppGpp accumulation and is conditionally required for antibiotic production in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Functional analysis of relA and rshA, two relA/spoT homologues of Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

cmdABCDEF, a cluster of genes encoding membrane proteins for differentiation and antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

hmgA, transcriptionally activated by HpdA, influences the biosynthesis of actinorhodin in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

Comparative analysis of expression of the Sal I restriction-modification system in Escherichia coli and Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

S-adenosyl-L-methionine activates actinorhodin biosynthesis by increasing autophosphorylation of the Ser/Thr protein kinase AfsK in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Binding study of AfsK, a Ser/Thr kinase from Streptomyces coelicolor A3(2) and S-adenosyl-L-methionine

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Green fluorescent protein as a reporter for spatial and temporal gene expression in Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

A novel family of proteins that regulates antibiotic production in streptomycetes appears to contain an OmpR-like DNA-binding fold

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Mutagenesis of the rapamycin producer Streptomyces hygroscopicus FC904.

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Improvement of transformation efficiency by strategic circumvention of restriction barriers in Streptomyces griseus.

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Connection between foreign DNA replication and induced expression of the restriction-modification system in Streptomyces aureofaciens

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

The restriction-modification system in Streptomyces flavopersicus

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Self-resistance mechanism in Streptomyces peucetius: overexpression of drrA, drrB and drrC for doxorubicin enhancement

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Involvement of a chromomycin ABC transporter system in secretion of a deacetylated precursor during chromomycin biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Mining microbial genomes for new natural products and biosynthetic pathways

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Genetics of Actinorhodin Biosynthesis by Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2).

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Identification of the antibiotic determined by the SCP1 plasmid of Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

The ECF sigma factor SigT regulates actinorhodin production in response to nitrogen stress in Streptomyces coelicolor

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

BldD from Streptomyces coelicolor is a non-essential global regulator that binds its own promoter as a dimer

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

A Streptomyces coelicolor antibiotic regulatory gene, absB, encodes an RNase III homolog

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Genetic mapping and characterization of novel mutations which suppress the effect of a relC mutation on antibiotic production in Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

SarA influences the sporulation and secondary metabolism in Streptomyces coelicolor M145.

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Erythromycin biosynthesis. Highly efficient incorporation of polyketide chain elongation intermediates into 6-deoxyerythronolide B in an engineered Streptomyces host

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.25

7 January 2021

Identifiers

DOI

10.1038/JA.2013.25

1 reference

Dimensions Publication ID

28 August 2017

0 references

1 reference