Crosstalk between the intestinal microbiota and the innate immune system in intestinal homeostasis and inflammatory bowel disease (Q38106562)

29 August 2017

Crosstalk between the intestinal microbiota and the innate immune system in intestinal homeostasis and inflammatory bowel disease (English)

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inflammatory bowel diseases

29 August 2017

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author name string

Jeremy Dupaul-Chicoine

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1

1 reference

29 August 2017

Maryse Dagenais

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2

1 reference

29 August 2017

Maya Saleh

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3

1 reference

29 August 2017

language of work or name

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1 September 2013

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Inflammatory Bowel Diseases

29 August 2017

1 reference

29 August 2017

19

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29 August 2017

2227-2237

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29 August 2017

10

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Reciprocal interactions of the intestinal microbiota and immune system.

29 August 2017

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Bifidobacteria can protect from enteropathogenic infection through production of acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The gut microbiota shapes intestinal immune responses during health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Induction of intestinal Th17 cells by segmented filamentous bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Regulatory T cells reinforce intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A framework for human microbiome research

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Diversity, stability and resilience of the human gut microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Unstable composition of the fecal microbiota in ulcerative colitis during clinical remission

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Genetics and pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Homeostasis and inflammation in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Intestinal development and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Intestinal mucosal barrier function in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Mucin dynamics and enteric pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Mucosal bacterial microflora and mucus layer thickness in adolescents with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Enteric defensins are essential regulators of intestinal microbial ecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Human -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Wnt signaling, stem cells, and cancer of the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

ER stress and the unfolded protein response in intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Effect of natural commensal-origin DNA on toll-like receptor 9 (TLR9) signaling cascade, chemokine IL-8 expression, and barrier integritiy of polarized intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Neutrophil function: from mechanisms to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

The role of neutrophils during intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Acquisition of antigen-presenting functions by neutrophils isolated from mice with chronic colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Biomarkers in inflammatory bowel disease: current practices and recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Ustekinumab induction and maintenance therapy in refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0B013E31828DCAC7

10.1097/MIB.0B013E31828DCAC7

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference