Aggrephagy: lessons from C. elegans (Q38110946)

29 August 2017

Aggrephagy: lessons from C. elegans (English)

1 reference

29 August 2017

Caenorhabditis elegans

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author name string

Qun Lu

series ordinal

1

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29 August 2017

Fan Wu

series ordinal

2

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29 August 2017

Hong Zhang

series ordinal

3

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29 August 2017

language of work or name

English

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publication date

1 June 2013

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29 August 2017

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29 August 2017

452

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29 August 2017

3

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29 August 2017

381-390

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Autophagy: from phenomenology to molecular understanding in less than a decade

29 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagosome formation: core machinery and adaptations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy, Immunity, and Microbial Adaptations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy: process and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Vesicular trafficking and autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Early endosomes and endosomal coatomer are required for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Role of autophagy in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

C. elegans screen identifies autophagy genes specific to multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Structural basis for sorting mechanism of p62 in selective autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Selective autophagic degradation of maternally-loaded germline P granule components in somatic cells during C. elegans embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

A ubiquitin-like system mediates protein lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

A protein conjugation system essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Characterization of a novel autophagy-specific gene, ATG29.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Organization of the pre-autophagosomal structure responsible for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Atg101, a novel mammalian autophagy protein interacting with Atg13

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The role of the Atg1/ULK1 complex in autophagy regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Hierarchy of Atg proteins in pre-autophagosomal structure organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

3D tomography reveals connections between the phagophore and endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Network organization of the human autophagy system

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Self-interaction is critical for Atg9 transport and function at the phagophore assembly site during autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

ei24, a p53 response gene involved in growth suppression and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The p53-induced gene Ei24 is an essential component of the basal autophagy pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

CUP-5, the C. elegans ortholog of the mammalian lysosomal channel protein MLN1/TRPML1, is required for proteolytic degradation in autolysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121721

21 January 2018

Identifiers

DOI

10.1042/BJ20121721

1 reference

29 August 2017

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