Linear ubiquitination-mediated NF-κB regulation and its related disorders (Q38130801)

29 August 2017

Linear ubiquitination-mediated NF-κB regulation and its related disorders (English)

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29 August 2017

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protein ubiquitination

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Fuminori Tokunaga

1

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29 August 2017

21 August 2013

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29 August 2017

Journal of Biochemistry

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29 August 2017

154

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29 August 2017

4

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29 August 2017

313-323

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

29 August 2017

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21 January 2018

Ubiquitin-like proteins

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The ubiquitin system for protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Linear ubiquitination: a novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The PUB domain functions as a p97 binding module in human peptide N-glycanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

NF-κB, the first quarter-century: remarkable progress and outstanding questions

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Regulation and function of NF-kappaB transcription factors in the immune system

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Diverse ubiquitin signaling in NF-κB activation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Regulation of NF-κB by ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

HOIL-1L interacting protein (HOIP) is essential for CD40 signaling

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Pattern recognition receptors and inflammation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Newly identified tumor-associated role of human Sharpin

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Functions of nuclear factor kappaB in bone

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Loss-of-function of SHARPIN causes an osteopenic phenotype in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Regulation of Parkin E3 ubiquitin ligase activity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Breaking the chains: structure and function of the deubiquitinases

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Deubiquitinases in the regulation of NF-κB signaling

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

A20: from ubiquitin editing to tumour suppression

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Frequent inactivation of A20 in B-cell lymphomas

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FJB%2FMVT079

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Structural Basis for Recognition of Diubiquitins by NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVT079

21 January 2018

Identifiers

DOI

10.1093/JB/MVT079

1 reference

29 August 2017

1 reference

PubMed ID

23969028