Role of autophagy in cancer prevention, development and therapy (Q38144288)

29 August 2017

Role of autophagy in cancer prevention, development and therapy (English)

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29 August 2017

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3

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29 August 2017

G Vignir Helgason

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Tessa Holyoake

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Tessa L Holyoake

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2

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language of work or name

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1 January 2013

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29 August 2017

Essays in Biochemistry

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29 August 2017

55

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29 August 2017

133-151

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Autophagy: from phenomenology to molecular understanding in less than a decade

29 August 2017

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https://api.crossref.org/works/10.1042%2FBSE0550133

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagosome formation: core machinery and adaptations

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy: process and function

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

The role of the Atg1/ULK1 complex in autophagy regulation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

At the acidic edge: emerging functions for lysosomal membrane proteins

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

mTOR signaling in growth control and disease

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

mTOR regulation of autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Ras is involved in the negative control of autophagy through the class I PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

The coordinate regulation of the p53 and mTOR pathways in cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Regulation of autophagy by cytoplasmic p53

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Effect of dual inhibition of apoptosis and autophagy in prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

The double-edged sword of autophagy modulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Dietary energy restriction in breast cancer prevention

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Caloric restriction delays disease onset and mortality in rhesus monkeys

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Caloric restriction reduces growth of mammary tumors and metastases

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Fasting enhances the response of glioma to chemo- and radiotherapy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

21 January 2018

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https://api.crossref.org/works/10.1042%2FBSE0550133

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0550133

21 January 2018

Identifiers

DOI

10.1042/BSE0550133

1 reference

29 August 2017

1 reference

PubMed ID

24070477