Glycosphingolipids: synthesis and functions (Q38155963)

29 August 2017

title

Glycosphingolipids: synthesis and functions (English)

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29 August 2017

1

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29 August 2017

Serena Capasso

2

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29 August 2017

Lucia Sticco

series ordinal

3

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29 August 2017

Domenico Russo

series ordinal

4

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29 August 2017

language of work or name

English

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publication date

25 October 2013

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29 August 2017

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29 August 2017

volume

280

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29 August 2017

issue

24

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29 August 2017

page(s)

6338-6353

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Archaeology. The Indus script--write or wrong?

29 August 2017

cites work

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Entropic evidence for linguistic structure in the Indus script

21 January 2018

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A primer in macromolecular linguistics

21 January 2018

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21 January 2018

The language of genes

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Deciphering the glycocode: the complexity and analytical challenge of glycomics

21 January 2018

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Glycomics: an overview of the complex glycocode

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12559

Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12559

Lysosomal lipid storage diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

A mouse B16 melanoma mutant deficient in glycolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

A vital role for glycosphingolipid synthesis during development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Structure and function of glycosphingolipids and sphingolipids: recollections and future trends

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Membrane lipids: where they are and how they behave

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ceramide synthases at the centre of sphingolipid metabolism and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Molecular machinery for non-vesicular trafficking of ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Transbilayer movement of monohexosylsphingolipids in endoplasmic reticulum and Golgi membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Involvement of murine β-1,4-galactosyltransferase V in lactosylceramide biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

The Lc3-synthase gene B3gnt5 is essential to pre-implantation development of the murine embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Remodeling of sphingolipids by plasma membrane associated enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

The sphingolipid salvage pathway in ceramide metabolism and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

LMSD: LIPID MAPS structure database

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

miRBase: integrating microRNA annotation and deep-sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

A Mathematical Theory of Communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Glycans: bioactive signals decoded by lectins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Regulated expression system for GD3 synthase cDNA and induction of differentiation in Neuro2a cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Glycolipid sialyltransferases are enhanced during neural differentiation of mouse embryonic carcinoma cells, P19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Membrane lipidome of an epithelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Alterations in ganglioside expression during the differentiation of human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Organization of the synthesis of glycolipid oligosaccharides in the Golgi complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Modulation of GalT1 and SialT1 sub-Golgi localization by SialT2 expression reveals an organellar level of glycolipid synthesis control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside glycosyltransferases organize in distinct multienzyme complexes in CHO-K1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Population context determines cell-to-cell variability in endocytosis and virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Enhanced insulin sensitivity in mice lacking ganglioside GM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Impairment of neuropsychological behaviors in ganglioside GM3-knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Complex gangliosides are essential in spermatogenesis of mice: possible roles in the transport of testosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

A functional role for complex gangliosides: motor deficits in GM2/GD2 synthase knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mice lacking major brain gangliosides develop parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Sphingolipids and expression regulation of genes in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Disialyl gangliosides enhance tumor phenotypes with differential modalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD1a negatively regulates matrix metalloproteinase-9 expression in mouse FBJ cell lines at the transcriptional level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD1a suppresses TNFalpha expression via Pkn1 at the transcriptional level in mouse osteosarcoma-derived FBJ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GD1a inhibits HGF-induced motility and scattering of cancer cells through suppression of tyrosine phosphorylation of c-Met

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of alpha3beta1 integrin with CD9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Regulation of human EGF receptor by lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside depletion and EGF responses of human GM3 synthase-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: demonstration in ldlD cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM3 inhibits hepatoma cell motility via down-regulating activity of EGFR and PI3K/AKT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Gangliosides influence EGFR/ErbB2 heterodimer stability but they do not modify EGF-dependent ErbB2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Cell growth regulation through GM3-enriched microdomain (glycosynapse) in human lung embryonal fibroblast WI38 and its oncogenic transformant VA13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM1 binds to the Trk protein and regulates receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Engagement of endogenous ganglioside GM1a induces tyrosine phosphorylation involved in neuron-like differentiation of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM3 participates in the pathological conditions of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Control of cell motility by interaction of gangliosides, tetraspanins, and epidermal growth factor receptor in A431 versus KB epidermoid tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

GSL-enriched membrane microdomains in innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Suppression of epidermal growth factor receptor signaling by protein kinase C-alpha activation requires CD82, caveolin-1, and ganglioside

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside induces caveolin-1 redistribution and interaction with the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Ganglioside GM2 modulates the erythrocyte Ca2+-ATPase through its binding to the calmodulin-binding domain and its 'receptor'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Carbohydrate to carbohydrate interaction in development process and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Probing specificity in carbohydrate-carbohydrate interactions with micelles and Langmuir monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Lipid rafts: elusive or illusive?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Revitalizing membrane rafts: new tools and insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Lipid raft heterogeneity: an enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Segregation of gangliosides GM1 and GD3 on cell membranes, isolated membrane rafts, and defined supported lipid monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Spatial and functional heterogeneity of sphingolipid-rich membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Analysis of detergent-resistant membranes associated with apical and basolateral GPI-anchored proteins in polarized epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Order of lipid phases in model and plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Glycosphingolipid structural analysis and glycosphingolipidomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Imaging mass spectrometry for visualization of drug and endogenous metabolite distribution: toward in situ pharmacometabolomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Shiga toxin 2 targets the murine renal collecting duct epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Protein-sphingolipid interactions within cellular membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

Developmental neuroscience: Miniature human brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12559

21 January 2018

Identifiers

DOI

10.1111/FEBS.12559

1 reference

29 August 2017

1 reference