Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells. (Q38160744)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24202444%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells (English)

1 reference

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29 February 2020

0 references

1

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Jose Manuel Gonzalez Sancho

29 February 2020

2

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29 February 2020

Alberto Munoz

6

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29 February 2020

author name string

Antonio Barbáchano

3

1 reference

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29 February 2020

Núria Niell

4

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29 February 2020

Gemma Ferrer-Mayorga

5

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29 February 2020

publication date

21 October 2013

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29 February 2020

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29 February 2020

volume

5

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29 February 2020

page(s)

1242-1260

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29 February 2020

issue

4

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Creative Commons Attribution 4.0 International

29 February 2020

copyright license

start time

21 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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1,25-Dihydroxyvitamin D3 induces expression of the Wnt signaling co-regulator LRP5 via regulatory elements located significantly downstream of the gene's transcriptional start site

6 September 2017

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A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

6 September 2017

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The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas.

6 September 2017

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Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Regulation of extrarenal synthesis of 1,25-dihydroxyvitamin D3--relevance for colonic cancer prevention and therapy.

6 September 2017

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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

6 September 2017

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Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

6 September 2017

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Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice

6 September 2017

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Beta-catenin affects androgen receptor transcriptional activity and ligand specificity

6 September 2017

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Identification of c-MYC as a target of the APC pathway

6 September 2017

1 reference

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Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

6 September 2017

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Do sunlight and vitamin D reduce the likelihood of colon cancer?

6 September 2017

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

6 September 2017

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TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.

6 September 2017

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Snail-1 regulates VDR signaling and inhibits 1,25(OH)-D₃ action in osteosarcoma

6 September 2017

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KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells

6 September 2017

1 reference

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The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression

6 September 2017

1 reference

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Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

1,25-Dihydroxyvitamin D3 regulates the expression of low-density lipoprotein receptor-related protein 5 via deoxyribonucleic acid sequence elements located downstream of the start site of transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

The molecular basis of vitamin D receptor and beta-catenin crossregulation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Expression of VDR and CYP24A1 mRNA in human tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

The down-regulation of the human MYC gene by the nuclear hormone 1alpha,25-dihydroxyvitamin D3 is associated with cycling of corepressors and histone deacetylases.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Dietary components modify gene expression: implications for carcinogenesis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

1alpha,25-(OH)(2)-D(3) and its synthetic analogue decrease tumor load in the Apc(min) Mouse.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

Vitamin D receptor expression as a predictive marker of biological behavior in human colorectal cancer.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

A comparison of trends of coronary heart disease mortality in Australia, USA and England and Wales with reference to three major risk factors-hypertension, cigarette smoking and diet

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FCANCERS5041242

Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FCANCERS5041242

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875938

A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

5 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FCANCERS5041242

Cancer stem cells: nature versus nurture

21 January 2018

1 reference

12 December 2020

Vitamin D receptor and cytokeratin expression may be progression indicators in human colon cancer

1 reference

12 December 2020

Wnt-dependent regulation of the E-cadherin repressor snail

1 reference

12 December 2020

VDR-mediated inhibition of DKK1 and SFRP2 suppresses adipogenic differentiation of murine bone marrow stromal cells

1 reference

12 December 2020

The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer

1 reference

12 December 2020

Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma

1 reference

12 December 2020

Identifiers

DOI

10.3390/CANCERS5041242

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24202444%20AND%20SRC:MED&resulttype=core&format=json

release_5gz3qzim7fhoflbhxqpuavkaru

29 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5gz3qzim7fhoflbhxqpuavkaru

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24202444%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24202444%20AND%20SRC:MED&resulttype=core&format=json