Innate immunity in systemic sclerosis pathogenesis (Q38161937)

30 August 2017

Innate immunity in systemic sclerosis pathogenesis (English)

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30 August 2017

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Steven O'Reilly

1

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PubMed ID

24219159

30 August 2017

language of work or name

English

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publication date

1 March 2014

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30 August 2017

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30 August 2017

126

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30 August 2017

5

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30 August 2017

329-337

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Systemic sclerosis: a prototypic multisystem fibrotic disorder

30 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Mortality in systemic sclerosis: an international meta-analysis of individual patient data

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Pathogen recognition and innate immunity

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20130367

How Toll-like receptors signal: what we know and what we don't know

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The evolution and genetics of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Systemic sclerosis and lupus: points in an interferon-mediated continuum

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Enhanced interleukin-10 production by dendritic cells upon stimulation with Toll-like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Differentiation potential of CD14+ monocytes into myofibroblasts in patients with systemic sclerosis

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20130367

Toll-like receptor signalling

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20130367

Immune signaling by RIG-I-like receptors

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20130367

Inferences, questions and possibilities in Toll-like receptor signalling

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20130367

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

TLRs and chronic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The extra domain A of fibronectin activates Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

TLR4 enhances TGF-beta signaling and hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Inhibiting toll-like receptor 4 signaling ameliorates pulmonary fibrosis during acute lung injury induced by lipopolysaccharide: an experimental study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

CCL18-stimulated upregulation of collagen production in lung fibroblasts requires Sp1 signaling and basal Smad3 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Gadolinium compounds signaling through TLR4 and TLR7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of nephrogenic systemic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

An Immunomodulatory GpG Oligonucleotide for the Treatment of Autoimmunity via the Innate and Adaptive Immune Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

An open-label pilot study of infliximab therapy in diffuse cutaneous systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

Genetic variation in Toll-like receptors and disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20130367

21 January 2018

Identifiers

DOI

10.1042/CS20130367

1 reference

30 August 2017

1 reference

PubMed ID

24219159