Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis. (Q38176187)

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4 March 2020

title

Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24394345%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

4 March 2020

main subject

prion protein family

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2

Neil R Cashman

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4 March 2020

author name string

Leslie I Grad

series ordinal

1

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4 March 2020

publication date

1 January 2014

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4 March 2020

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4 March 2020

volume

8

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4 March 2020

issue

1

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4 March 2020

page(s)

33-41

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

4 March 2020

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Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme

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Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

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Deadly conformations--protein misfolding in prion disease

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Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.

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Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis

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Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.

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Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice

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12 December 2020

Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

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12 December 2020

Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase

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Genetics of amyotrophic lateral sclerosis

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12 December 2020

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

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Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy

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Identifiers

DOI

10.4161/PRI.27602

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24394345%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24394345%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

24394345

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