TP53 mutation analysis in clinical practice: lessons from chronic lymphocytic leukemia (Q38177771)

30 August 2017

title

TP53 mutation analysis in clinical practice: lessons from chronic lymphocytic leukemia (English)

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30 August 2017

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Jitka Malcikova

1

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30 August 2017

Sarka Pavlova

series ordinal

2

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30 August 2017

Katerina Stano Kozubik

series ordinal

3

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30 August 2017

Sarka Pospisilova

series ordinal

4

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30 August 2017

language of work or name

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5 February 2014

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30 August 2017

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30 August 2017

volume

35

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30 August 2017

issue

6

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30 August 2017

page(s)

663-671

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Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia

30 August 2017

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TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.

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21 January 2018

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21 January 2018

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Next-generation sequencing transforms today's biology

21 January 2018

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Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial.

21 January 2018

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Determination of optimal conditions for analysis of p53 status in leukemic cells using functional analysis of separated alleles in yeast.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Germline TP53 mutations and Li-Fraumeni syndrome

21 January 2018

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Loss of p53 impedes the antileukemic response to BCR-ABL inhibition

21 January 2018

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21 January 2018

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TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia

21 January 2018

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TP53 mutation and survival in chronic lymphocytic leukemia

21 January 2018

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21 January 2018

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21 January 2018

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Robustness of Amplicon Deep Sequencing Underlines Its Utility in Clinical Applications

21 January 2018

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A subset of Binet stage A CLL patients with TP53 abnormalities and mutated IGHV genes have stable disease

21 January 2018

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7 January 2021

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

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7 January 2021

p53 lesions in leukemic transformation

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7 January 2021

p53 abnormalities in CLL are associated with excess of prolymphocytes and poor prognosis

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7 January 2021

The BCR-ABL1 T315I mutation and additional genomic aberrations are dominant genetic lesions associated with disease progression in patients with chronic myelogenous leukemia resistant to tyrosine kinase inhibitor therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22508

7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

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https://api.crossref.org/works/10.1002%2FHUMU.22508

7 January 2021

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22508

7 January 2021

Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia

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7 January 2021

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22508

7 January 2021

Missense mutations located in structural p53 DNA-binding motifs are associated with extremely poor survival in chronic lymphocytic leukemia

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7 January 2021

How little is too much? p53 inactivation: from laboratory cutoff to biological basis of chemotherapy resistance

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7 January 2021

TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

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7 January 2021

Identifiers

DOI

10.1002/HUMU.22508

1 reference

30 August 2017

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