The balance of intestinal Foxp3+ regulatory T cells and Th17 cells and its biological significance (Q38183860)

30 August 2017

title

The balance of intestinal Foxp3+ regulatory T cells and Th17 cells and its biological significance (English)

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30 August 2017

Xiaofei Shen

1

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30 August 2017

Junfeng Du

series ordinal

2

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30 August 2017

Wenxian Guan

series ordinal

3

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30 August 2017

Yong Zhao

series ordinal

4

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30 August 2017

publication date

3 February 2014

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Expert Review of Clinical Immunology

30 August 2017

published in

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30 August 2017

volume

10

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30 August 2017

issue

3

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30 August 2017

page(s)

353-362

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Coordination of tolerogenic immune responses by the commensal microbiota

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The role of the immune system in governing host-microbe interactions in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Reciprocal interactions of the intestinal microbiota and immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Peripheral education of the immune system by colonic commensal microbiota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

GM-CSF: the secret weapon in the T(H)17 arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Signaling of interleukin-17 family cytokines in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Th17 and regulatory T cells in mediating and restraining inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Development and functional specialization of CD103+ dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal CD103+ dendritic cells: master regulators of tolerance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The puzzle of intestinal lamina propria dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Retinoic acid attenuates ileitis by restoring the balance between T-helper 17 and T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Has the microbiota played a critical role in the evolution of the adaptive immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The gut microbiota shapes intestinal immune responses during health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Induction of lamina propria Th17 cells by intestinal commensal bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Induction of intestinal Th17 cells by segmented filamentous bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A microbial symbiosis factor prevents intestinal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Induction of colonic regulatory T cells by indigenous Clostridium species

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

FOXP3 and RORγt: transcriptional regulation of Treg and Th17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

SMAD2 is essential for TGF beta-mediated Th17 cell generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Induction and molecular signature of pathogenic TH17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The role of retinoic acid in tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Retinoic acid promotes the development of Arg1-expressing dendritic cells for the regulation of T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Antigen-presenting cell production of IL-10 inhibits T-helper 1 and 17 cell responses and suppresses colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Regulatory lymphocytes and intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal homeostasis and its breakdown in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

The membrane-bound mucin Muc1 regulates T helper 17-cell responses and colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Late developmental plasticity in the T helper 17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal bacteria and the regulation of immune cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Unravelling the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Innate and adaptive immunity in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Analysis of inflammatory signals in Japanese children with Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Targets for new immunomodulation strategies in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

TGF-beta1 and Smad7 in the regulation of IBD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Specific targeting of IL-6 signalling pathway: a new way to treat IBD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Role of IL-17A in the development of colitis-associated cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A protective role by interleukin-17F in colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Th17 cells induce colitis and promote Th1 cell responses through IL-17 induction of innate IL-12 and IL-23 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Induction of systemic immunity by expression of interleukin-23 in murine colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL-23/IL-17 immunity as a hallmark of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Molecular Gastronomy: How to Make the Critical Intestinal Foxp3+ Treg Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.882232

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

21 January 2018

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI33194

Identifiers

DOI

10.1586/1744666X.2014.882232

1 reference

30 August 2017

1 reference