Targeting RNA polymerase I to treat MYC-driven cancer. (Q38194418)

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10 March 2020

review article

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title

Targeting RNA polymerase I to treat MYC-driven cancer (English)

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10 March 2020

3

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10 March 2020

author name string

G Poortinga

series ordinal

1

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10 March 2020

L M Quinn

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2

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10 March 2020

language of work or name

English

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publication date

10 March 2014

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10 March 2020

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10 March 2020

volume

34

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10 March 2020

issue

4

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10 March 2020

page(s)

403-412

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Dysregulation of the basal RNA polymerase transcription apparatus in cancer

10 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Cancer epigenetics: from mechanism to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The Myc oncoprotein as a therapeutic target for human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MYC-induced cancer cell energy metabolism and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MYC in oncogenesis and as a target for cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc proteins as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Therapeutic Targeting of Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Direct activation of RNA polymerase III transcription by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MYC recruits the TIP60 histone acetyltransferase complex to chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Widespread microRNA repression by Myc contributes to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc: Maestro of MicroRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc influences global chromatin structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Analysis of Myc-induced histone modifications on target chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Acting locally and globally: Myc's ever-expanding roles on chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MYC on the path to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The c-myc promoter: still MysterY and challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

21 January 2018

You Don't Muck with MYC

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Catabolite activator protein: DNA binding and transcription activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Silencing c-MYC expression by targeting quadruplex in P1 promoter using locked nucleic acid trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting MYC Expression through G-Quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Genomic c-Myc quadruplex DNA selectively kills leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting MYC dependence in cancer by inhibiting BET bromodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting MYCN in neuroblastoma by BET bromodomain inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Sequence-specific DNA binding by the c-Myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Low molecular weight inhibitors of Myc-Max interaction and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc as a therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Improved low molecular weight Myc-Max inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc inhibition negatively impacts lymphoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

In Vitro Cytotoxicity and In Vivo Efficacy, Pharmacokinetics, and Metabolism of 10074-G5, a Novel Small-Molecule Inhibitor of c-Myc/Max Dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Modelling Myc inhibition as a cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Endogenous Myc maintains the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The new biomimetic chemistry: artificial transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc's other life: stem cells and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Regression of murine lung tumors by the let-7 microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting MYC-Regulated miRNAs to Combat Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Functional genomics identifies therapeutic targets for MYC-driven cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Heterogeneity in MYC-induced mammary tumors contributes to escape from oncogene dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Disentangling the MYC web.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Identification of novel Myc target genes with a potential role in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Global mapping of c-Myc binding sites and target gene networks in human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Crosstalk between c-Myc and ribosome in ribosomal biogenesis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The Myc/Max/Mad network and the transcriptional control of cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Genomic targets of the human c-Myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Transcriptional amplification in tumor cells with elevated c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A library of gene expression signatures to illuminate normal and pathological lymphoid biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A large scale genetic analysis of c-Myc-regulated gene expression patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Evolution of the holozoan ribosome biogenesis regulon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Control of cell proliferation by Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The role of c-myc in cellular growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc enhances protein synthesis and cell size during B lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc regulates mammalian body size by controlling cell number but not cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The role of c-myc in regulation of translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc target genes involved in cell growth, apoptosis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Of mice and Myc: c-Myc and mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc and Max homologs in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Drosophila myc regulates cellular growth during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

dMyc is required for larval growth and endoreplication in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The Myc trilogy: lord of RNA polymerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

RNA polymerases I and III, growth control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

A role for c-Myc in the regulation of ribosomal RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc induces changes in higher order rDNA structure on stimulation of quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Chromatin states at ribosomal DNA loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

UBF levels determine the number of active ribosomal RNA genes in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The RNA polymerase I transcription machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Epigenetic regulation of TTF-I-mediated promoter-terminator interactions of rRNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

c-Myc regulates transcriptional pause release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Does the ribosome translate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Synthesis of the translational apparatus is regulated at the translational level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Internal ribosome entry sites in eukaryotic mRNA molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Translational control in cellular and developmental processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The multifunctional nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The nucleolus under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The nucleolus: an emerging target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

p53 is covalently linked to 5.8S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Signaling to p53: ribosomal proteins find their way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Regulation of HDM2 activity by the ribosomal protein L11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

21 January 2018

1 reference

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Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation

21 January 2018

1 reference

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Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5

21 January 2018

1 reference

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A critical role for noncoding 5S rRNA in regulating Mdmx stability

21 January 2018

1 reference

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Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint.

21 January 2018

1 reference

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Ribosomal protein S7 is both a regulator and a substrate of MDM2

21 January 2018

1 reference

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Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function

21 January 2018

1 reference

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Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

21 January 2018

1 reference

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Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

21 January 2018

1 reference

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Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.

21 January 2018

1 reference

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Regulation of nucleolar signalling to p53 through NEDDylation of L11

21 January 2018

1 reference

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MDMX: from bench to bedside

21 January 2018

1 reference

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Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

21 January 2018

1 reference

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Guarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathway

21 January 2018

1 reference

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A new PICTure of nucleolar stress.

21 January 2018

1 reference

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Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

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Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

21 January 2018

1 reference

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Revisiting the nucleolus: from marker to dynamic integrator of cancer signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Chemotherapeutic drugs inhibit ribosome biogenesis at various levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

Targeting RNA polymerase I transcription and the nucleolus for cancer therapy

21 January 2018

1 reference

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MYC as a regulator of ribosome biogenesis and protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.13

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

21 January 2018

1 reference

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Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers

21 January 2018

1 reference

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

2 references

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21 January 2018

12 December 2020

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

2 references

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21 January 2018

12 December 2020

MYC degradation: deubiquitinating enzymes enter the dance

1 reference

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31 March 2020

All things to all people

1 reference

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Activation by c-Myc of transcription by RNA polymerases I, II and III.

31 March 2020

1 reference

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c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism

31 March 2020

1 reference

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Targeting the nucleolus for cancer-specific activation of p53.

31 March 2020

1 reference

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Drugging the undruggable: transcription therapy for cancer

31 March 2020

1 reference

12 December 2020

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer

1 reference

12 December 2020

Myc target transcriptomes

1 reference

12 December 2020

Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc

1 reference

12 December 2020

Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model

1 reference

12 December 2020

The life cycle of C-myc: from synthesis to degradation

1 reference

12 December 2020

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

1 reference

12 December 2020

The Drosophila F box protein archipelago regulates dMyc protein levels in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608428%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1002318019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608428%20AND%20SRC:MED&resulttype=core&format=json