MYC in oncogenesis and as a target for cancer therapies (Q37732974)

22 August 2017

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title

MYC in oncogenesis and as a target for cancer therapies (English)

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Marie Arsenian-Henriksson

22 August 2017

author

series ordinal

3

object named as

Marie Arsenian Henriksson

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22 August 2017

Ami Albihn

1

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22 August 2017

John Inge Johnsen

series ordinal

2

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22 August 2017

language of work or name

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1 January 2010

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Advances in Cancer Research

22 August 2017

published in

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22 August 2017

volume

107

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22 August 2017

page(s)

163-224

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Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action

22 August 2017

cites work

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7 January 2021

c-Myc is necessary for DNA damage-induced apoptosis in the G(2) phase of the cell cycle

1 reference

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7 January 2021

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

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7 January 2021

c-Myc-dependent etoposide-induced apoptosis involves activation of Bax and caspases, and PKCdelta signaling

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7 January 2021

New wirings in the survivin networks

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7 January 2021

Myc and the cell cycle

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7 January 2021

The functions of animal microRNAs

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7 January 2021

The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

1 reference

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7 January 2021

c-Myc is essential for hematopoietic stem cell differentiation and regulates Lin(-)Sca-1(+)c-Kit(-) cell generation through p21.

1 reference

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7 January 2021

Etoposide, topoisomerase II and cancer

1 reference

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7 January 2021

Thermodynamics of protein-protein interactions of cMyc, Max, and Mad: effect of polyions on protein dimerization.

1 reference

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7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

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7 January 2021

Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days

1 reference

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7 January 2021

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Medulloblastoma growth inhibition by hedgehog pathway blockade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Improving survival and reducing toxicity with chemotherapy in advanced non-small cell lung cancer : a realistic goal?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Transformation of human and murine fibroblasts without viral oncoproteins

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Epstein-Barr virus and the pathogenesis of Burkitt's lymphoma: more questions than answers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Triple negative breast cancer--current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc versus USF: discrimination at the cad gene is determined by core promoter elements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc represses transcription through recruitment of DNA methyltransferase corepressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Advances in hormonal therapy for breast cancer

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Widespread microRNA repression by Myc contributes to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYC in breast tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

miR-15 and miR-16 induce apoptosis by targeting BCL2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYCN amplification remains prognostically strong 20 years after its “clinical debut”

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Estrogen regulation of vascular endothelial growth factor in breast cancer in vitro and in vivo: the role of estrogen receptor alpha and c-Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Have you seen...?: Micro-managing and restraining pluripotent stem cells by MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYC-induced cancer cell energy metabolism and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A role for AID in chromosome translocations between c-myc and the IgH variable region.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

STI571 (Gleevec) as a paradigm for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Insulin-like growth factor 1 (IGF-1)-induced twist expression is involved in the anti-apoptotic effects of the IGF-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Development of pulmonary bronchiolo-alveolar adenocarcinomas in transgenic mice overexpressing murine c-myc and epidermal growth factor in alveolar type II pneumocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

HER2-positive breast cancer: current and future treatment strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Reversible tumorigenesis by MYC in hematopoietic lineages

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Wnt/beta-catenin signaling in cancer stemness and malignant behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Changing trends of research and treatment in infant neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Immunosuppressive, antiviral and antitumor activities of cytarabine derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Binding and suppression of the Myc transcriptional activation domain by p107.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc proteins as therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Creation of human tumour cells with defined genetic elements

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cancer stem cells and survival pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Clinical applications of anticancer drugs targeted to topoisomerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Expression and activity of L-Myc in normal mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Rhabdomyosarcoma in children

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A microRNA polycistron as a potential human oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Molecular biology of Burkitt's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Multiple cell-type-specific elements regulate Myc protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A conserved element in Myc that negatively regulates its proapoptotic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The MYC oncogene as a cancer drug target

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification of CDK4 as a target of c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Negative regulation of the mammalian UV response by Myc through association with Miz-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Chemotherapy for lung cancer: the state of the art in 2009.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

p53 may mediate the mdr-1 expression via the WT1 gene in human vincristine-resistant leukemia/lymphoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Sonic hedgehog in the nervous system: functions, modifications and mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Participation of cyclin A in Myc-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Traps to catch unwary oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Human MicroRNA targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Embryonal neural tumours and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

RAS is regulated by the let-7 microRNA family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The let-7 microRNA represses cell proliferation pathways in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Embryonic stem cell-specific microRNAs promote induced pluripotency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc functionally cooperates with Bax to induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mechanisms of MYC stabilization in human malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

CIP2A inhibits PP2A in human malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYC-dependent regulation and prognostic role of CIP2A in gastric cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Skp2 regulates Myc protein stability and activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

An extended transcriptional network for pluripotency of embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Local intracoronary administration of antisense oligonucleotide against c-myc for the prevention of in-stent restenosis: results of the randomized investigation by the Thoraxcenter of antisense DNA using local delivery and IVUS after coronary stenti

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Modified magrath regimens for adults with Burkitt and Burkitt-like lymphomas: preserved efficacy with decreased toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc represses transcription of the growth arrest gene gas1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYCtranslocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Adjuvant chemotherapy for breast cancer--30 years later

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Prediction of mammalian microRNA targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The Myc-nucleophosmin-ARF network: a complex web unveiled

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The MYCN oncoprotein as a drug development target

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mechanisms of drug resistance in cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Targeting tumor specific translocations in sarcomas in pediatric patients for immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

PRIMA-1 synergizes with adriamycin to induce cell death in non-small cell lung cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

1 reference

7 January 2021

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

An international evaluation of CODOX-M and CODOX-M alternating with IVAC in adult Burkitt's lymphoma: results of United Kingdom Lymphoma Group LY06 study

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Reflecting on 25 years with MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc overexpression enhances apoptosis induced by small molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc and beta-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYCN deregulation as a potential target for novel therapies in rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of ALK signaling for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Pediatric brain tumors: current treatment strategies and future therapeutic approaches

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Imatinib mesylate (Gleevec/Glivec) a molecular-targeted therapy for chronic myeloid leukaemia and other malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Human small-cell lung cancers show amplification and expression of the N-myc gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYC oncogenes and human neoplastic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mutation status and clinical outcome of 89 imatinib mesylate-resistant chronic myelogenous leukemia patients: a retrospective analysis from the French intergroup of CML (Fi(phi)-LMC GROUP)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Relevance of high-dose chemotherapy in solid tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc pathways provoking cell suicide and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Adenovirus-mediated gene therapy specific for small cell lung cancer cells using a Myc-Max binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc-regulated microRNAs modulate E2F1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification of Mad as a repressor of the human telomerase (hTERT) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Generation of germline-competent induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

miR-19 is a key oncogenic component of mir-17-92

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Activation of Akt predicts poor outcome in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The myc oncogene: MarvelouslY Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-MYC: more than just a matter of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Micromanipulating cancer: microRNA-based therapeutics?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

An alternative pathway for gene regulation by Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Rational design of shepherdin, a novel anticancer agent.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Prediction of central nervous system embryonal tumour outcome based on gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cancer therapeutics: targeting the dark side of Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The ubiquitin-specific protease USP28 is required for MYC stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc as a therapeutic target in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The anthracycline antibiotics: antitumor drugs that alter chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inactivation of hCDC4 can cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MYC is a metastasis gene for non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Retinoid therapy of childhood cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Defying death after DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Medulloblastoma: from molecular pathology to therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The intersection of Epstein-Barr virus with the germinal center

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The links between axin and carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Retracted: An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Adaptive hypersensitivity to estrogen: mechanism for superiority of aromatase inhibitors over selective estrogen receptor modulators for breast cancer treatment and prevention

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

An unsteady scaffold for Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Childhood solid tumours: a developmental disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Inhibition of c-Myc down-regulation by sustained extracellular signal-regulated kinase activation prevents the antimetabolite methotrexate- and gemcitabine-induced differentiation in non-small-cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Disabling c-Myc in childhood medulloblastoma and atypical teratoid/rhabdoid tumor cells by the potent G-quadruplex interactive agent S2T1-6OTD.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Epidermal growth factor receptor mutations in lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

1 reference

7 January 2021

Cancerous miRNAs and their regulation

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https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Bevacizumab in the treatment of breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Modelling Myc inhibition as a cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc potentiates apoptosis by stimulating Bax activity at the mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Repression of p15INK4b expression by Myc through association with Miz-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The role of INI1/hSNF5 in gene regulation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Regulation of N-myc expression in development and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Aberrant activation of notch signaling in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Adult Burkitt's and Burkitt-like non-Hodgkin's lymphoma--outcome for patients treated with high-dose therapy and autologous stem-cell transplantation in first remission or at relapse: results from the European Group for Blood and Marrow Transplantat

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The MYCN enigma: significance of MYCN expression in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Stable and unstable pools of Myc protein exist in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Recent developments in cell-based immune therapy for neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The Myc oncoprotein as a therapeutic target for human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A microRNA expression signature of human solid tumors defines cancer gene targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Imatinib-refractory gastrointestinal stromal tumors: the clinical problem and therapeutic strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Mnt takes control as key regulator of the myc/max/mxd network

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Improved low molecular weight Myc-Max inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Advances in the diagnosis and treatment of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Cell cycle control of embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

First-line chemotherapy in metastatic small-cell lung cancer (SCLC).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Gene amplification of c-myc and N-myc in small cell carcinoma of the lung

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A credit-card library approach for disrupting protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Low molecular weight inhibitors of Myc-Max interaction and function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Distinct Roles for MAX Protein Isoforms in Proliferation and Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

Differential expression of myc family genes during murine development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2810%2907006-5

7 January 2021

10.1016/S0065-230X(10)07006-5

Identifiers

DOI

1 reference

22 August 2017

1 reference