Dysfunctional autophagy in Alzheimer's disease: pathogenic roles and therapeutic implications (Q38194496)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610177%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

review article

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title

Dysfunctional autophagy in Alzheimer's disease: pathogenic roles and therapeutic implications (English)

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10 March 2020

0 references

0 references

2

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10 March 2020

author name string

Jun-Hua Liang

series ordinal

1

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10 March 2020

publication date

7 March 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610177%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

published in

Neuroscience Bulletin

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10 March 2020

volume

30

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10 March 2020

issue

2

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10 March 2020

page(s)

308-316

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Neuronal autophagy in cerebral ischemia

10 March 2020

cites work

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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

6 September 2017

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6 September 2017

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6 September 2017

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Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.

6 September 2017

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6 September 2017

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Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner

6 September 2017

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6 September 2017

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6 September 2017

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

6 September 2017

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Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

6 September 2017

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Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

6 September 2017

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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

6 September 2017

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

6 September 2017

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Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

6 September 2017

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Autophagy promotes synapse development in Drosophila

6 September 2017

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A gene network regulating lysosomal biogenesis and function

6 September 2017

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Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila

6 September 2017

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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

6 September 2017

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

6 September 2017

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Autophagy fights disease through cellular self-digestion

6 September 2017

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Autophagy in the Pathogenesis of Disease

6 September 2017

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Autophagy, amyloidogenesis and Alzheimer disease

6 September 2017

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Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

6 September 2017

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Emerging roles for ubiquitin and protein degradation in neuronal function

6 September 2017

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Neuronal macroautophagy: from development to degeneration

6 September 2017

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

6 September 2017

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

6 September 2017

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Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

6 September 2017

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Lithium induces autophagy by inhibiting inositol monophosphatase

6 September 2017

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Synaptic protein degradation by the ubiquitin proteasome system

6 September 2017

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

6 September 2017

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6 September 2017

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Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

6 September 2017

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In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

6 September 2017

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Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system

6 September 2017

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

6 September 2017

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Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport

6 September 2017

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Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells

6 September 2017

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Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.

14 September 2017

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A comprehensive glossary of autophagy-related molecules and processes

14 September 2017

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Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.

14 September 2017

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Regulation of neuronal autophagy in axon: implication of autophagy in axonal function and dysfunction/degeneration

14 September 2017

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Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats

14 September 2017

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Regulation of presynaptic neurotransmission by macroautophagy

28 September 2017

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Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

31 August 2018

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31 August 2018

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31 August 2018

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Rapamycin alleviates toxicity of different aggregate-prone proteins

31 August 2018

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Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

31 August 2018

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31 August 2018

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Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

31 August 2018

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A light and electron microscopic study of the cellular response to axonal injury in the superior cervical ganglion of the rat

1 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24610177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aberrant membranes and double-membrane structures accumulate in the axons of Atg5-null Purkinje cells before neuronal death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24610177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24610177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12264-013-1418-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610177%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610177%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

24610177

1 reference