DEP domains: structurally similar but functionally different (Q38205108)

31 August 2017

title

DEP domains: structurally similar but functionally different (English)

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31 August 2017

Madelon M Maurice

2

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author name string

Sarah V Consonni

series ordinal

1

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31 August 2017

Johannes L Bos

series ordinal

3

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31 August 2017

publication date

16 April 2014

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Nature Reviews Molecular Cell Biology

31 August 2017

published in

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31 August 2017

volume

15

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31 August 2017

issue

5

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31 August 2017

page(s)

357-362

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Why cytoplasmic signalling proteins should be recruited to cell membranes.

31 August 2017

cites work

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Cell signaling in space and time: where proteins come together and when they're apart

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Conformational stability studies of the pleckstrin DEP domain: definition of the domain boundaries.

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Structure and dynamics of the human pleckstrin DEP domain: distinct molecular features of a novel DEP domain subfamily

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Pleckstrin's repeat performance: a novel domain in G-protein signaling?

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Dynamic recruitment of axin by Dishevelled protein assemblies

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Domains of axin and disheveled required for interaction and function in wnt signaling.

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SH2 domains, interaction modules and cellular wiring

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Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

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Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway

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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

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cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane

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Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

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Crystal structure of the multifunctional Gβ5–RGS9 complex

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Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors

31 March 2020

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Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

31 March 2020

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Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

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Multiple functions of segment polarity genes in Drosophila

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Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1.

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The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

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Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

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Wnt regulation of planar cell polarity (PCP).

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Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling

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Intramolecular interaction between the DEP domain of RGS7 and the Gbeta5 subunit

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The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In Vivo

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The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling

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DEP-domain-mediated regulation of GPCR signaling responses.

31 March 2020

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The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7

31 March 2020

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

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31 March 2020

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31 March 2020

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Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

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Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

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Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein betagamma subunits and PKA.

31 March 2020

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Pleckstrin associates with plasma membranes and induces the formation of membrane projections: requirements for phosphorylation and the NH2-terminal PH domain

31 March 2020

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The G protein-coupled receptor repertoires of human and mouse

31 March 2020

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DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

31 March 2020

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FYVE-finger proteins--effectors of an inositol lipid

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24739740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pleckstrin's repeat performance: a novel domain in G-protein signaling?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24739740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM3791

1 reference

Dimensions Publication ID

31 August 2017

1014983106

0 references

1 reference