Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte. (Q38207092)

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16 March 2020

3 references

30 January 2021

8 April 2021

13 January 2024

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte (English)

1 reference

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regulation of gene expression

16 March 2020

main subject

1 reference

biomedical investigative technique

8 September 2019

1 reference

19 September 2019

1 reference

12 October 2019

1 reference

11 December 2019

1 reference

19 December 2019

intracellular receptor

1 reference

21 December 2019

1 reference

22 December 2019

epithelial to mesenchymal transition

1 reference

30 January 2021

1 reference

8 April 2021

1 reference

8 April 2021

1

1 reference

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16 March 2020

Laura Amicone

2

1 reference

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16 March 2020

Alessandra Marchetti

4

1 reference

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16 March 2020

Carmine Mancone

5

1 reference

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16 March 2020

Marco Tripodi

6

1 reference

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16 March 2020

author name string

Tonino Alonzi

3

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publication date

20 May 2014

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16 March 2020

1 February 2015

3 references

30 January 2021

8 April 2021

13 January 2024

11 references

8 September 2019

19 September 2019

12 October 2019

11 December 2019

19 December 2019

21 December 2019

22 December 2019

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16 March 2020

30 January 2021

8 April 2021

13 January 2024

35

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16 March 2020

issue

2

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16 March 2020

page(s)

302-310

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

16 March 2020

copyright license

10 references

8 September 2019

19 September 2019

12 October 2019

11 December 2019

19 December 2019

21 December 2019

22 December 2019

30 January 2021

8 April 2021

TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice

13 January 2024

cites work

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Col1A1 production and apoptotic resistance in TGF-β1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells

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Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation

6 September 2017

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The mesenchymal-to-epithelial transition in somatic cell reprogramming

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TGFβ overrides HNF4α tumor suppressing activity through GSK3β inactivation: implication for hepatocellular carcinoma gene therapy.

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HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines

6 September 2017

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Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors.

6 September 2017

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Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

6 September 2017

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Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

6 September 2017

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Deregulation of hepatocyte nuclear factor 4 (HNF4)as a marker of epithelial tumors progression

6 September 2017

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Hallmarks of Cancer: The Next Generation

6 September 2017

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Molecular determinants of liver zonation

6 September 2017

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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

6 September 2017

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Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells

6 September 2017

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Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

6 September 2017

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Epithelial-to-mesenchymal transitions in the liver

6 September 2017

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Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

6 September 2017

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Liver regeneration: alternative epithelial pathways

6 September 2017

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A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

6 September 2017

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Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

6 September 2017

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The basics of epithelial-mesenchymal transition

6 September 2017

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TGF-beta-induced epithelial to mesenchymal transition

6 September 2017

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A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

6 September 2017

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Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

6 September 2017

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

6 September 2017

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Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers

6 September 2017

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

6 September 2017

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Transitions between epithelial and mesenchymal states in development and disease

6 September 2017

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

6 September 2017

1 reference

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Identification and expansion of human colon-cancer-initiating cells

6 September 2017

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Evolution of cancer stem cells

6 September 2017

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Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

6 September 2017

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TGF-beta and epithelial-to-mesenchymal transitions

6 September 2017

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The Snail genes as inducers of cell movement and survival: implications in development and cancer.

6 September 2017

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Hypothesis: cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?

6 September 2017

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Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma

6 September 2017

1 reference

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Control of pancreas and liver gene expression by HNF transcription factors

6 September 2017

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Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells

6 September 2017

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The snail superfamily of zinc-finger transcription factors

6 September 2017

1 reference

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Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail

6 September 2017

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

6 September 2017

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6 September 2017

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The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

6 September 2017

1 reference

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

6 September 2017

1 reference

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Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells

6 September 2017

1 reference

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Coexistence of C/EBP alpha, beta, growth-induced proteins and DNA synthesis in hepatocytes during liver regeneration. Implications for maintenance of the differentiated state during liver growth

6 September 2017

1 reference

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Impaired energy homeostasis in C/EBP alpha knockout mice

6 September 2017

1 reference

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Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transition

6 September 2017

1 reference

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The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

6 September 2017

1 reference

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Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

14 September 2017

1 reference

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Proteomic analysis reveals a major role for contact inhibition in the terminal differentiation of hepatocytes

14 September 2017

1 reference

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TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling.

14 September 2017

1 reference

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Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro

14 September 2017

1 reference

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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

14 September 2017

1 reference

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Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGF(beta) is abrogated by pre-treatment with the heritable differentiation effector FGF1.

14 September 2017

1 reference

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E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma

28 September 2017

1 reference

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C/EBP alpha: a critical regulator of genes governing integrative metabolic processes

28 September 2017

1 reference

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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

28 September 2017

1 reference

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Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes

23 June 2018

1 reference

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An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.

23 June 2018

1 reference

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Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation.

31 August 2018

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Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.

31 August 2018

1 reference

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Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

31 August 2018

1 reference

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Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo

31 August 2018

1 reference

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Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.

31 August 2018

1 reference

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Control of cell behavior during vertebrate development by Slug, a zinc finger gene.

31 August 2018

1 reference

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HNF4: A central regulator of hepatocyte differentiation and function

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FLIV.12577

The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes

21 January 2018

1 reference

12 December 2020

Differential patterns of expression of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats

1 reference

12 December 2020

Snail controls differentiation of hepatocytes by repressing HNF4α expression

1 reference

12 December 2020

CD133+ hepatic stellate cells are progenitor cells

1 reference

12 December 2020

Identifiers

DOI

10.1111/LIV.12577

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766136%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766136%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766136%20AND%20SRC:MED&resulttype=core&format=json