Mass spectrometry-based biomarkers in drug development (Q38222153)

31 August 2017

Mass spectrometry-based biomarkers in drug development (English)

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31 August 2017

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Ronald A Miller

1

1 reference

PubMed ID

24952191

31 August 2017

Daniel S Spellman

series ordinal

2

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PubMed ID

24952191

31 August 2017

language of work or name

English

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publication date

1 January 2014

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Advances in Experimental Medicine and Biology

31 August 2017

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31 August 2017

806

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31 August 2017

341-359

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Mass spectrometry-based proteomics

31 August 2017

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https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

The human plasma proteome: history, character, and diagnostic prospects

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Protein identification by mass spectrometry: issues to be considered

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Platforms for enrichment of phosphorylated proteins and peptides in proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Biological microarray interpretation: the rules of engagement

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

The need for guidelines in publication of peptide and protein identification data: Working Group on Publication Guidelines for Peptide and Protein Identification Data.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

BRCA1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Protein microarrays and novel detection platforms

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Preparation of stable isotope-incorporated peptide internal standards for field desorption mass spectrometry quantification of peptides in biologic tissue.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Measurement of enkephalin peptides in canine brain regions, teeth, and cerebrospinal fluid with high-performance liquid chromatography and mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Delineation of prognostic biomarkers in prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

The price of innovation: new estimates of drug development costs

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Affinity separation and enrichment methods in proteomic analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Clinical biomarkers in drug discovery and development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Place of pattern in proteomic biomarker discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Aptamer-based multiplexed proteomic technology for biomarker discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Target site occupancy: emerging generalizations from clinical and preclinical studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

A proteomic method for the analysis of changes in protein concentrations in response to systemic perturbations using metabolic incorporation of stable isotopes and mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

The US Food and Drug Administration perspective on cancer biomarker development.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Assessment of reproducibility in depletion and enrichment workflows for plasma proteomics using label-free quantitative data-independent LC-MS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Peer Reviewed: Top-Down Proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Accelerating drug development using biomarkers: a case study with sitagliptin, a novel DPP4 inhibitor for type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Assigning significance in label-free quantitative proteomics to include single-peptide-hit proteins with low replicates

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Food and drug administration's critical path initiative and innovations in drug development paradigm: Challenges, progress, and controversies

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Recent advances in multiplex immunoassays

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Impact of biomarker development on drug safety assessment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Positron emission tomography molecular imaging for drug development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Quantitative analysis of complex peptide mixtures using FTMS and differential mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Serum protein markers for early detection of ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Multidimensional LC separations in shotgun proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

A survey of computational methods and error rate estimation procedures for peptide and protein identification in shotgun proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Analysis, statistical validation and dissemination of large-scale proteomics datasets generated by tandem MS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

31 March 2020

Whole genome sequencing

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https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Mass spectrometric-based approaches in quantitative proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Dynamics of protein turnover, a missing dimension in proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Two-dimensional gel electrophoresis in proteomics: old, old fashioned, but it still climbs up the mountains

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Cutting the cost of drug development?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Protein biomarker discovery and validation: the long and uncertain path to clinical utility

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Statistical models for protein validation using tandem mass spectral data and protein amino acid sequence databases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Determining target engagement in living systems

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Decoding protein modifications using top-down mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Novel approach for peptide quantitation and sequencing based on 15N and 13C metabolic labeling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Protein profiling of human postmortem brain using 2-dimensional fluorescence difference gel electrophoresis (2-D DIGE).

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Drug quantitation on a benchtop liquid chromatography-tandem mass spectrometry system

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Serum peptide profiling by magnetic particle-assisted, automated sample processing and MALDI-TOF mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Five years of GWAS discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Strategic approach to fit-for-purpose biomarkers in drug development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Integral membrane proteins and bilayer proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Quantitative liquid chromatographic-tandem mass spectrometric determination of orlistat in plasma with a quadrupole ion trap

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

The role of imaging in proof of concept for CNS drug discovery and development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Metabolic labeling of mammalian organisms with stable isotopes for quantitative proteomic analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

Pharmaceutical and clinical analysis by tandem mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

In vivo quantitative proteomics: the SILAC mouse.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-06068-2_16

10.1007/978-3-319-06068-2_16

31 March 2020

Identifiers

DOI

1 reference

31 August 2017

1 reference

PubMed ID

24952191