How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions? (Q38255067)

1 September 2017

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title

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions? (English)

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1 September 2017

H Lincet

1

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1 September 2017

P Icard

series ordinal

2

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1 September 2017

language of work or name

English

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publication date

29 September 2014

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1 September 2017

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1 September 2017

volume

34

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1 September 2017

issue

29

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1 September 2017

page(s)

3751-3759

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https://scigraph.springernature.com/pub.10.1038/onc.2014.320

1 September 2017

exact match

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cites work

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Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase as a therapeutic target

31 March 2020

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Subcellular dynamics of multifunctional protein regulation: mechanisms of GAPDH intracellular translocation

31 March 2020

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Acetylation control of metabolic enzymes in cancer: an updated version.

31 March 2020

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SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation.

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Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation

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Glyceraldehyde 3-phosphate dehydrogenase is a SET-binding protein and regulates cyclin B-cdk1 activity

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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

31 March 2020

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GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.

31 March 2020

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Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

31 March 2020

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Comparative proteomic profiling of human bile reveals SSP411 as a novel biomarker of cholangiocarcinoma

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Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

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Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase

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Evidence for an alternative glycolytic pathway in rapidly proliferating cells

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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

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Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.

31 March 2020

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Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms

31 March 2020

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PKM2 contributes to cancer metabolism

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PKM2 and ACVR 1C are prognostic markers for poor prognosis of gallbladder cancer

31 March 2020

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Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma

31 March 2020

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Nuclear PKM2 expression predicts poor prognosis in patients with esophageal squamous cell carcinoma

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Emerging roles of PKM2 in cell metabolism and cancer progression

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Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis.

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2

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PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

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Pyruvate kinase M2 and cancer: an updated assessment

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

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Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

31 March 2020

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Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization

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Regulation and function of pyruvate kinase M2 in cancer

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c-Myc and cancer metabolism

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Mucins in cancer: function, prognosis and therapy

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MUC1: a multifaceted oncoprotein with a key role in cancer progression

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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

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Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

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31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters

31 March 2020

1 reference

12 December 2020

Down-regulation of phosphoglucose isomerase/autocrine motility factor enhances gensenoside Rh2 pharmacological action on leukemia KG1α cells

1 reference

12 December 2020

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression

1 reference

12 December 2020

Expression and secretion of neuroleukin/phosphohexose isomerase/maturation factor as autocrine motility factor by tumor cells.

1 reference

12 December 2020

A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells

1 reference

12 December 2020

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

1 reference

12 December 2020

Subcellular localization of aldolase B

1 reference

12 December 2020

Differential expression of MUC1, MUC2, and MUC5AC in carcinomas of various sites: an immunohistochemical study

1 reference

12 December 2020

Overexpression of the autocrine motility factor/phosphoglucose isomerase induces transformation and survival of NIH-3T3 fibroblasts

1 reference

12 December 2020

Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma.

1 reference

12 December 2020

Tissue-specific expression of rat aldolase A mRNAs. Three molecular species differing only in the 5'-terminal sequences.

1 reference

12 December 2020

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

1 reference

12 December 2020

A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucl

1 reference

12 December 2020

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

1 reference

12 December 2020

Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide

1 reference

12 December 2020

MUC1: a novel metabolic master regulator

1 reference

12 December 2020

Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells

1 reference

12 December 2020

Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors.

1 reference

12 December 2020

PKM2, STAT3 and HIF-1α: The Warburg's vicious circle

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.320

1 reference

Dimensions Publication ID

1 September 2017

1013378291

0 references

1 reference