Human Th1 dichotomy: origin, phenotype and biologic activities (Q38256942)

1 September 2017

Human Th1 dichotomy: origin, phenotype and biologic activities (English)

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1 September 2017

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1

Francesco Annunziato

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1 September 2017

Lorenzo Cosmi

2

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1 September 2017

Francesco Liotta

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3

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1 September 2017

Enrico Maggi

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4

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1 September 2017

Sergio Romagnani

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5

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1 September 2017

5 October 2014

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1 September 2017

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Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

1 September 2017

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

21 January 2018

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Phenotypic and functional features of human Th17 cells

21 January 2018

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Effector T cell plasticity: flexibility in the face of changing circumstances

21 January 2018

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Defining the human T helper 17 cell phenotype.

21 January 2018

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

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Toll-like receptors and innate immunity

21 January 2018

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Interleukin-18 regulates both Th1 and Th2 responses

21 January 2018

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Induction of TH1 and TH2 responses: a key role for the 'natural' immune response?

21 January 2018

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Novel IL-12 family members shed light on the orchestration of Th1 responses

21 January 2018

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Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

21 January 2018

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Transcriptional regulation of Th1/Th2 polarization

21 January 2018

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Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

21 January 2018

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Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages

21 January 2018

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

21 January 2018

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Human 60-kDa heat shock protein is a target autoantigen of T cells derived from atherosclerotic plaques

21 January 2018

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Lymphokine production by human T cells in disease states

21 January 2018

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21 January 2018

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

21 January 2018

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

21 January 2018

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Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

21 January 2018

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

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TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells

21 January 2018

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T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

21 January 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

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Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

21 January 2018

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Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

21 January 2018

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The biological functions of T helper 17 cell effector cytokines in inflammation

21 January 2018

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APC-derived cytokines and T cell polarization in autoimmune inflammation

21 January 2018

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Helper T cell differentiation enters a new era: le roi est mort; vive le roi!

21 January 2018

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Distinct regulation of interleukin-17 in human T helper lymphocytes

21 January 2018

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

21 January 2018

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

21 January 2018

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Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

21 January 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

21 January 2018

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Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis

21 January 2018

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Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation

21 January 2018

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IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells.

21 January 2018

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IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells.

21 January 2018

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Cutting edge: the pathogenicity of IFN-γ-producing Th17 cells is independent of T-bet

21 January 2018

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IL-1β promotes the differentiation of polyfunctional human CCR6+CXCR3+ Th1/17 cells that are specific for pathogenic and commensal microbes

21 January 2018

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A TH1-->TH2 switch is a critical step in the etiology of HIV infection

21 January 2018

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Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

21 January 2018

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

21 January 2018

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CD4+CD161+ T lymphocytes infiltrate Crohn's disease-associated perianal fistulas and are reduced by anti-TNF-α local therapy

21 January 2018

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Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

21 January 2018

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Induction and molecular signature of pathogenic TH17 cells

21 January 2018

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

21 January 2018

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T cell expression of granulocyte-macrophage colony-stimulating factor in juvenile arthritis is contingent upon Th17 plasticity.

21 January 2018

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Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids.

21 January 2018

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

21 January 2018

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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

21 January 2018

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Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis

21 January 2018

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Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation

21 January 2018

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

21 January 2018

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Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

21 January 2018

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Modulators of the nuclear receptor retinoic acid receptor-related orphan receptor-γ (RORγ or RORc)

21 January 2018

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Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts

21 January 2018

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Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

21 January 2018

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A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

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The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557671

Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.

5 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557671

Role of Th1 and Th2 cells in neurologic disorders.

5 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557671

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

5 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557671

Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production

5 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557671

CCR5 is characteristic of Th1 lymphocytes

5 November 2018

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IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones

21 January 2018

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12 December 2020

Human TH1 and TH2 subsets: doubt no more

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12 December 2020

What can stochastic resonance do?

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12 December 2020

Polyinosinic acid: polycytidylic acid promotes T helper type 1-specific immune responses by stimulating macrophage production of interferon-alpha and interleukin-12

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12 December 2020

Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns

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12 December 2020

Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction

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12 December 2020

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

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12 December 2020

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

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12 December 2020

The Autoimmune Infiltrate of Basedow's Disease: Analysis at Clonal Level and Comparison with Hashimoto's Thyroiditis

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12 December 2020

Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis

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12 December 2020

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

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12 December 2020

Brief report: etanercept inhibits the tumor necrosis factor α-driven shift of Th17 lymphocytes toward a nonclassic Th1 phenotype in juvenile idiopathic arthritis

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12 December 2020

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