Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity (Q38261202)

1 September 2017

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title

Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity (English)

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1 September 2017

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2

Steven C Almo

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1 September 2017

Dibyendu Samanta

1

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1 September 2017

19 October 2014

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Cellular and Molecular Life Sciences

1 September 2017

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1 September 2017

72

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1 September 2017

4

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1 September 2017

645-658

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https://scigraph.springernature.com/pub.10.1007/s00018-014-1763-4

1 September 2017

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cites work

Molecular and functional analysis of cadherin-based adherens junctions

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Adherens junctions: from molecules to morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Biology and pathology of nectins and nectin-like molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The role of nectins in different types of cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Immunoglobulin superfamily receptors and adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The molecular structure of cell adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Paradigms for glycan-binding receptors in cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Thinking outside the cell: how cadherins drive adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Cadherin-mediated cell-cell adhesion: sticking together as a family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Cadherins in development: cell adhesion, sorting, and tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin and afadin: novel organizers of intercellular junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Structure and biochemistry of cadherins and catenins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

21 January 2018

12 December 2020

Linking molecular affinity and cellular specificity in cadherin-mediated adhesion.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

E-N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin: an adhesion molecule involved in formation of synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Host factors and measles virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin 4 is the epithelial cell receptor for measles virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Functional Classification of Immune Regulatory Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Contacts between the commissural axons and the floor plate cells are mediated by nectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectins establish a checkerboard-like cellular pattern in the auditory epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Role of cell adhesion molecule nectin-3 in spermatid development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Mouse homolog of poliovirus receptor-related gene 2 product, mPRR2, mediates homophilic cell aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Defects in nuclear and cytoskeletal morphology and mitochondrial localization in spermatozoa of mice lacking nectin-2, a component of cell-cell adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin ectodomain structures reveal a canonical adhesive interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Crystal Structure of the cis-Dimer of Nectin-1: IMPLICATIONS FOR THE ARCHITECTURE OF CELL-CELL JUNCTIONS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

CD28/B7 system of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

A role for PVRL4-driven cell-cell interactions in tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin-4 is a new histological and serological tumor associated marker for breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

DNAX Accessory Molecule-1 Mediated Recognition of Freshly Isolated Ovarian Carcinoma by Resting Natural Killer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Accelerated tumor growth in mice deficient in DNAM-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

CD226 Gly307Ser association with multiple autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Successful administration of ipilimumab to two kidney transplantation patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Mutations in herpes simplex virus glycoprotein D that prevent cell entry via nectins and alter cell tropism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Different receptors binding to distinct interfaces on herpes simplex virus gD can trigger events leading to cell fusion and viral entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuela

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Autosomal recessive ectodermal dysplasia: I. An undescribed dysplasia/malformation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

On the inheritance of the split hand/split foot malformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

A comprehensive genetic association study of Alzheimer disease in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

The cell adhesion gene PVRL3 is associated with congenital ocular defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Role of the second immunoglobulin-like loop of nectin in cell–cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1763-4

Cleft lip and palate, pili torti, malformed ears, partial syndactyly of fingers and toes, and mental retardation: a new syndrome?

21 January 2018

1 reference

12 December 2020

Recent advances using anti-CTLA-4 for the treatment of melanoma

1 reference

12 December 2020

Adherens junction protein nectin-4 is the epithelial receptor for measles virus

1 reference

12 December 2020

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity

1 reference

12 December 2020

Nectinopathies: an emerging group of ectodermal dysplasia syndromes

1 reference

12 December 2020

Bioinformatic characterization of the SynCAM family of immunoglobulin-like domain-containing adhesion molecules

1 reference

12 December 2020

10.1007/S00018-014-1763-4

Identifiers

DOI

1 reference

1 September 2017

1 reference

PubMed ID

25326769