Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling (Q38289224)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18632682%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling (English)

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10 January 2020

8

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10 January 2020

author name string

Mark Lal

1

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10 January 2020

Xuewen Song

2

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10 January 2020

Jennifer L Pluznick

3

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10 January 2020

Valeria Di Giovanni

4

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10 January 2020

David M Merrick

5

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10 January 2020

Norman D Rosenblum

6

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10 January 2020

Veronique Chauvet

7

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10 January 2020

York Pei

9

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10 January 2020

Michael J Caplan

10

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10 January 2020

publication date

16 July 2008

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10 January 2020

published in

Human Molecular Genetics

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10 January 2020

volume

17

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10 January 2020

issue

20

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10 January 2020

page(s)

3105-3117

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Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion

10 January 2020

cites work

1 reference

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

6 September 2017

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Molecular pathogenesis of ADPKD: the polycystin complex gets complex

6 September 2017

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Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

6 September 2017

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Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

6 September 2017

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New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies

6 September 2017

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Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes

6 September 2017

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WNT and beta-catenin signalling: diseases and therapies

6 September 2017

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A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells

6 September 2017

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Recent advances in the cell biology of polycystic kidney disease

6 September 2017

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Genetics and pathogenesis of polycystic kidney disease.

6 September 2017

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Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins

6 September 2017

1 reference

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Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin

6 September 2017

1 reference

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Adhesion signaling: how beta-catenin interacts with its partners

6 September 2017

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The genetics and physiology of polycystic kidney disease

6 September 2017

1 reference

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Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722884

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

6 September 2017

1 reference

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Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

6 September 2017

1 reference

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Three-dimensional structure of the armadillo repeat region of beta-catenin

6 September 2017

1 reference

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Elevated c-myc protooncogene expression in autosomal recessive polycystic kidney disease

6 September 2017

1 reference

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Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

6 September 2017

1 reference

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The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells

6 September 2017

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Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722884

Polycystin-1 activates the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway

14 September 2017

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Aberrant polycystin-1 expression results in modification of activator protein-1 activity, whereas Wnt signaling remains unaffected

14 September 2017

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The polycystic kidney disease 1 gene product modulates Wnt signaling

14 September 2017

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Overexpression of PKD1 causes polycystic kidney disease

27 September 2017

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c-myc as an inducer of polycystic kidney disease in transgenic mice

23 June 2018

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Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant

23 June 2018

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Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD).

31 August 2018

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Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin

31 August 2018

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Cyst formation and growth in autosomal dominant polycystic kidney disease

1 October 2018

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12 December 2020

Localization of overexpressed c-myc mRNA in polycystic kidneys of the cpk mouse

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12 December 2020

beta-Catenin and plakoglobin N- and C-tails determine ligand specificity

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12 December 2020

Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease

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12 December 2020

Polycystic kidney disease

1 reference

12 December 2020

A "two-hit" model of cystogenesis in autosomal dominant polycystic kidney disease?

1 reference

12 December 2020

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

1 reference

12 December 2020

Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects

1 reference

12 December 2020

The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDN208

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10 January 2020

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10 January 2020

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