Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site. (Q38292654)

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English	Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site.	scientific article

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4 January 2020

Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site (English)

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4 January 2020

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Susanna Harju-Baker

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4 January 2020

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Flávia C Costa

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4 January 2020

Halyna Fedosyuk

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4 January 2020

Renee Neades

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4 January 2020

Kenneth R Peterson

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17 March 2008

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4 January 2020

Molecular and Cellular Biology

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4 January 2020

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4 January 2020

3101-3113

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4 January 2020

Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation

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6 September 2017

Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice

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6 September 2017

Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

1 reference

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6 September 2017

Genome architecture of the human beta-globin locus affects developmental regulation of gene expression

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6 September 2017

{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice

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6 September 2017

GATA-1 forms distinct activating and repressive complexes in erythroid cells

1 reference

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6 September 2017

FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1.

1 reference

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6 September 2017

Adult stage gamma-globin silencing is mediated by a promoter direct repeat element

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A standard curve based method for relative real time PCR data processing

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Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus

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6 September 2017

Mi-2/NuRD: multiple complexes for many purposes

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6 September 2017

An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer

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Sp1 and Egr1 regulate transcription of the Dmrt1 gene in Sertoli cells

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Quantitative analysis of globin gene induction in single human erythroleukemic cells

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6 September 2017

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters

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6 September 2017

Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice

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6 September 2017

Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4

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NuRD and SIN3 histone deacetylase complexes in development

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The "dark side" of chromatin remodeling: repressive effects on transcription

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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

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FKLF, a novel Krüppel-like factor that activates human embryonic and fetal beta-like globin genes

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Regulation of embryonic/fetal globin genes by nuclear hormone receptors: a novel perspective on hemoglobin switching.

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The A gamma-globin 3' element provides no unique function(s) for human beta-globin locus gene regulation

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6 September 2017

Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion

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6 September 2017

Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice

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6 September 2017

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

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Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells

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6 September 2017

Role of gene order in developmental control of human gamma- and beta-globin gene expression

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6 September 2017

Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines

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Developmental regulation of human gamma-globin genes in transgenic mice

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6 September 2017

Phosphorylation of the erythroid transcription factor GATA-1.

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6 September 2017

Biochemical characterization of the developmental stage- and tissue-specific erythroid transcription factor, NF-E4.

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6 September 2017

GATA1 and YY1 are developmental repressors of the human epsilon-globin gene

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6 September 2017

Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein

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6 September 2017

Enhancers increase the probability but not the level of gene expression

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Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants

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6 September 2017

Terminal differentiation of murine erythroleukemia cells: physical stabilization of end-stage cells

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6 September 2017

Promoter sequences required for function of the human gamma globin gene in erythroid cells

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6 September 2017

Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene

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6 September 2017

G to A substitution in the distal CCAAT box of the A gamma-globin gene in Greek hereditary persistence of fetal haemoglobin

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6 September 2017

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice

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6 September 2017

A fetal globin gene mutation in A gamma nondeletion hereditary persistence of fetal hemoglobin increases promoter strength in a nonerythroid cell

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6 September 2017

Structure and function of the enhancer 3' to the human A gamma globin gene

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6 September 2017

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

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6 September 2017

Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene

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6 September 2017

A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin

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6 September 2017

Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1.

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14 September 2017

Analysis of the mechanism of action of non-deletion hereditary persistence of fetal hemoglobin mutants in transgenic mice

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14 September 2017

Phosphorylation of GATA-1 increases its DNA-binding affinity and is correlated with induction of human K562 erythroleukaemia cells

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14 September 2017

Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.

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14 September 2017

Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.

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14 September 2017

MBD2 is a critical component of a methyl cytosine-binding protein complex isolated from primary erythroid cells

1 reference

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14 September 2017

FOG-1 represses GATA-1-dependent FcepsilonRI beta-chain transcription: transcriptional mechanism of mast-cell-specific gene expression in mice

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14 September 2017

Erythroid-induced commitment of K562 cells results in clusters of differentially expressed genes enriched for specific transcription regulatory elements

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14 September 2017

Inhibitor of hematopoietic cell proliferation derived from a human leukemic cell line

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14 September 2017

A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells

1 reference

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27 September 2017

Correct function of the locus control region may require passage through a nonerythroid cellular environment.

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27 September 2017

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

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23 June 2018

CONTINUOUS CULTURE OF HUMAN LYMPHOBLASTS FROM PERIPHERAL BLOOD OF A CHILD WITH ACUTE LEUKEMIA.

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23 June 2018

Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423176

23 June 2018

Developmental regulation of beta-globin gene switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423176

23 June 2018

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

1 reference

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23 June 2018

Demonstration of a human epsilon-globin gene silencer with studies in transgenic mice

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23 June 2018

Importance of globin gene order for correct developmental expression.

1 reference

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23 June 2018

Human gamma- to beta-globin gene switching in transgenic mice.

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23 June 2018

Hematopoiesis in the embryonic mouse spleen. II. Alterations after phenylhydrazine administration to the mothers

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23 June 2018

The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

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31 August 2018

Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.

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31 August 2018

LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.

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31 August 2018

Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.

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31 August 2018

Autonomous developmental control of human embryonic globin gene switching in transgenic mice.

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31 August 2018

Sensitive ribonuclease protection assay employing glycogen as a carrier and a single inactivation/precipitation step

1 reference

https://pubmed.ncbi.nlm.nih.gov/18347053

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18347053

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-globin stage selector element factor is erythroid-specific promoter/enhancer binding protein NF-E4

1 reference

https://pubmed.ncbi.nlm.nih.gov/18347053

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human γ-globin genes silenced independently of other genes in the β-globin locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18347053

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repressed by a NuRD

1 reference

https://pubmed.ncbi.nlm.nih.gov/18347053

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01858-07

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18347053%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18347053%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18347053%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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