Thinking small: towards microRNA-based therapeutics for anxiety disorders (Q38310488)

2 September 2017

1 reference

title

Thinking small: towards microRNA-based therapeutics for anxiety disorders (English)

1 reference

2 September 2017

1 reference

3

1 reference

2 September 2017

Gerard M Moloney

4

0 references

Karen A Scott

Karen A Scott

1

0 references

John F. Cryan

John F Cryan

6

0 references

Timothy G. Dinan

Timothy G Dinan

5

0 references

Alan E Hoban

2

Alan E Hoban

1 reference

2 September 2017

language of work or name

English

0 references

publication date

8 January 2015

1 reference

Expert Opinion on Investigational Drugs

2 September 2017

published in

1 reference

2 September 2017

volume

24

1 reference

2 September 2017

issue

4

1 reference

2 September 2017

page(s)

529-542

1 reference

The global burden of mental disorders: an update from the WHO World Mental Health (WMH) surveys

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

50 years of hurdles and hope in anxiolytic drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The age of anxiety: role of animal models of anxiolytic action in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

PTSD in the military: special considerations for understanding prevalence, pathophysiology and treatment following deployment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Imaging genetics of anxiety disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Genetics of anxiety and trauma-related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Translational approaches to anxiety: focus on genetics, fear extinction and brain imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Anxiety disorders in primary care

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The pharmacologic treatment of anxiety disorders: a review of progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The GABA system in anxiety and depression and its therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Anxiolytic drug discovery: what are the novel approaches and how can we improve them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Metabotropic glutamate receptor 7: at the interface of cognition and emotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Bringing a developmental perspective to anxiety genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Chronic non-invasive corticosterone administration abolishes the diurnal pattern of tph2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Lost in translation. New unexplored avenues for neuropsychopharmacology: epigenetics and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Pharmacology of epigenetics in brain disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA history: discovery, recent applications, and next frontiers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

microRNAs in cancer management.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Clinical applications for microRNAs in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Posttranscriptional upregulation by microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNAs: Meta-controllers of gene expression in synaptic activity emerge as genetic and diagnostic markers of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA-target interactions: new insights from genome-wide approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNAs: small RNAs with a big role in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA dysregulation in psychiatric disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

21 January 2018

MicroRNA therapeutics.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA profiling: approaches and considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Circulating microRNAs: Association with disease and potential use as biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Lifetime experiences, the brain and personalized medicine: an integrative perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MiR-122 in hepatic function and liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Small RNAs in human brain development and disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

RNA mechanisms in CNS systems and disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Blood microRNA changes in depressed patients during antidepressant treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

When less is more--microRNAs and psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Neurobehavioral, neuropathological and biochemical profiles in a novel mouse model of co-morbid post-traumatic stress disorder and mild traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Chronic academic stress increases a group of microRNAs in peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The origin, function, and diagnostic potential of extracellular microRNAs in human body fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

High resolution of microRNA signatures in human whole saliva.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Extracellular microRNA: a new source of biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Proteomic profiling of exosomes: current perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Circulating microRNAs as stable blood-based markers for cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Role of microRNAs in central nervous system development and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNAs as biomarkers for CNS disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

miRNA expression profiles in cerebrospinal fluid and blood of patients with acute ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The Comorbidity of Major Depression and Anxiety Disorders: Recognition and Management in Primary Care

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Animal models of neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Animal models of social stress: effects on behavior and brain neurochemical systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Animal models of depression and anxiety: What do they tell us about human condition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The ascent of mouse: advances in modelling human depression and anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Environmental enrichment modulates glucocorticoid receptor expression and reduces anxiety in Indian field male mouse Mus booduga through up-regulation of microRNA-124a

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Acute stress alters amygdala microRNA miR-135a and miR-124 expression: inferences for corticosteroid dependent stress response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Changes in brain MicroRNAs contribute to cholinergic stress reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA-182 regulates amygdala-dependent memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Environmental enrichment upregulates micro-RNA-183 and alters acetylcholinesterase splice variants to reduce anxiety-like behavior in the little Indian field mouse (Mus booduga).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

microRNA-34c is a novel target to treat dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Behavioural consequences of two chronic psychosocial stress paradigms: anxiety without depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Stress induces region specific alterations in microRNAs expression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Micro-managing the circadian clock: The role of microRNAs in biological timekeeping

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Serum and amygdala microRNA signatures of posttraumatic stress: fear correlation and biomarker potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Progress in microRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Non-coding RNAs in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Treatment of HCV infection by targeting microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

Systemic delivery of tyrosine-mutant AAV vectors results in robust transduction of neurons in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

MicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs. non-learned helplessness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2014.997873

10.1517/13543784.2014.997873

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference