The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells (Q38349193)

2 September 2017

title

The oncogene Nup98-HOXA9 induces gene transcription in myeloid cells (English)

1 reference

2 September 2017

The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

21 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

neoplastic gene expression regulation

21 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

21 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

21 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

21 March 2024

3

Troy Camarata

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

21 March 2024

author name string

Ghada Ghannam

1

1 reference

2 September 2017

Akiko Takeda

2

1 reference

2 September 2017

Agnes Viale

5

1 reference

2 September 2017

Malcolm A. Moore

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

21 March 2024

Nabeel R. Yaseen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

21 March 2024

language of work or name

English

0 references

publication date

15 October 2003

1 reference

full work available at URL

2 September 2017

http://www.jbc.org/content/279/2/866.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14561764

https://api.elsevier.com/content/article/PII:S0021925818526946?httpAccept=text/xml

21 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

https://api.elsevier.com/content/article/PII:S0021925818526946?httpAccept=text/plain

21 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

https://syndication.highwire.org/content/doi/10.1074/jbc.M307280200

21 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307280200

Journal of Biological Chemistry

21 March 2024

published in

1 reference

2 September 2017

volume

279

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2 September 2017

issue

2

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2 September 2017

page(s)

866-875

1 reference

Transcription factor fusions in acute leukemia: variations on a theme.

2 September 2017

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A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

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Nup98 is a mobile nucleoporin with transcription-dependent dynamics

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The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR.

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The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

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The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways

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CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

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AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins

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Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression

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NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

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A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

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21 January 2018

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21 January 2018

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Identifiers

1 reference

2 September 2017

1 reference