Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis (Q38352939)

2 September 2017

Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis (English)

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2 September 2017

Levi J Beverly

1

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PubMed ID

12842084

2 September 2017

Anthony J Capobianco

series ordinal

2

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2 September 2017

1 June 2003

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2 September 2017

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2 September 2017

3

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2 September 2017

6

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2 September 2017

551-564

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Functional Analysis of the TAN-1 Gene, a Human Homolog of Drosophila Notch

2 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch signaling in leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch pathway: making sense of suppressor of hairless

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Genomic organization and 5' regulatory region of the mouse IL-2 receptor beta-chain gene (IL-2Rb).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch signaling in T cell development

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Ikaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The Ikaros gene is required for the development of all lymphoid lineages

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Identification of CDK4 as a target of c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

An intronic Ikaros-binding element mediates retinoic acid suppression of the kappa opioid receptor gene, accompanied by histone deacetylation on the promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Signalling downstream of activated mammalian Notch

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Neoplastic transformation by Notch requires nuclear localization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Structure and distribution of the Notch protein in developing Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

A molecular dissection of the repression circuitry of Ikaros

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch receptors and hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Identity of the beta-globin locus control region binding protein HS2NF5 as the mammalian homolog of the notch-regulated transcription factor suppressor of hairless.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch signaling: from the outside in

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Delta-notch signaling and Drosophila cell fate choice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Developmental signaling. Vertebrate ligands for Notch.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

The notch pathway: modulation of cell fate decisions in hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

p300 acts as a transcriptional coactivator for mammalian Notch-1

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch activation of yan expression is antagonized by RTK/pointed signaling in the Drosophila eye.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900137-5

7 January 2021

10.1016/S1535-6108(03)00137-5

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

12842084