Macrophage phenotypic plasticity in atherosclerosis: The associated features and the peculiarities of the expression of inflammatory genes (Q38371352)

2 September 2017

1 reference

https://doi.org/10.1016/j.ijcard.2020.12.067

1 reference

29 December 2023

title

Macrophage phenotypic plasticity in atherosclerosis: The associated features and the peculiarities of the expression of inflammatory genes (English)

1 reference

2 September 2017

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phenotypic plasticity

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1 reference

5

1 reference

2 September 2017

6

Alexander N Orekhov

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2 September 2017

2

Yuri V Bobryshev

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2 September 2017

Dimitry A Chistiakov

1

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2 September 2017

Nikita G Nikiforov

series ordinal

3

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2 September 2017

Natalia V Elizova

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

5 March 2015

1 reference

International Journal of Cardiology

2 September 2017

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2 September 2017

184

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2 September 2017

436-445

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Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

2 September 2017

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Inflammation, atherosclerosis, and coronary artery disease

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Monocyte/macrophage accumulation and smooth muscle cell phenotypes in early atherosclerotic lesions of human aorta

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Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia

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7-ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages

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Bioactive products generated by group V sPLA(2) hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines

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Flagellin or lipopolysaccharide treatment modified macrophage populations after colorectal radiation of rats.

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Computational identification of potential transcriptional regulators of TGF-ß1 in human atherosclerotic arteries.

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Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

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CXCL4-induced plaque macrophages can be specifically identified by co-expression of MMP7+S100A8+ in vitro and in vivo.

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Oxidized low-density lipoprotein induces differentiation of RAW264.7 murine macrophage cell line into dendritic-like cells

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Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein

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Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation.

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Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense

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Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

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Distribution of macrophage polarization markers in human atherosclerosis

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Macrophages in immunopathology of atherosclerosis: a target for diagnostics and therapy.

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Specificity of action of colony-stimulating factors in the differentiation of granulocytes and macrophages

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Electrophilic fatty acids regulate matrix metalloproteinase activity and expression.

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PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

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A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.

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Non-redundant roles for LXRalpha and LXRbeta in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice

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Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice

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Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions

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Macrophages in the pathogenesis of atherosclerosis

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Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages

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An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors

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Loss of the lysophosphatidylcholine effector, G2A, ameliorates aortic atherosclerosis in low-density lipoprotein receptor knockout mice.

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Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery

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Mechanisms and consequences of macrophage apoptosis in atherosclerosis

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Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.

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MicroRNA-145 Targeted Therapy Reduces Atherosclerosis

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Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization

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A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association

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Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

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Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages

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Monocyte and macrophage dynamics during atherogenesis

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Widespread distribution of HLA-DR-expressing cells in macroscopically undiseased intima of the human aorta: a possible role in surveillance and maintenance of vascular homeostasis

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Macrophage activation and polarization

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30 December 2023

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NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis

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Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A

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Changes of lysosomes in the earliest stages of the development of atherosclerosis.

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CD1 expression and the nature of CD1-expressing cells in human atherosclerotic plaques

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Oxidative stress modulates KLF6Full and its splice variants.

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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

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LXR-dependent gene expression is important for macrophage survival and the innate immune response

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Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway

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30 December 2023

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Fluid-phase pinocytosis of LDL by macrophages: a novel target to reduce macrophage cholesterol accumulation in atherosclerotic lesions

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Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease.

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Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.

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Liver X Receptor Signaling Pathways in Cardiovascular Disease

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Inflammation: a role for NR4A orphan nuclear receptors?

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Palmitic acid enhances lectin-like oxidized LDL receptor (LOX-1) expression and promotes uptake of oxidized LDL in macrophage cells

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Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling

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Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids

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30 December 2023

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Macrophage scavenger receptors.

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30 December 2023

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Mapping of vascular dendritic cells in atherosclerotic arteries suggests their involvement in local immune-inflammatory reactions.

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30 December 2023

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ABCA1 protein enhances Toll-like receptor 4 (TLR4)-stimulated interleukin-10 (IL-10) secretion through protein kinase A (PKA) activation

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HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

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30 December 2023

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Phenotypic polarization of macrophages in atherosclerosis

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Atherosclerosis — An Inflammatory Disease

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Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein

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30 December 2023

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Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

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30 December 2023

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CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages

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Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

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30 December 2023

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CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells

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Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment

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30 December 2023

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LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8.

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Macrophages, oxysterols and atherosclerosis

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Mapping and characterization of the binding site for specific oxidized phospholipids and oxidized low density lipoprotein of scavenger receptor CD36.

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Induction of Krüppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I.

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Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB

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The adenosine-dependent angiogenic switch of macrophages to an M2-like phenotype is independent of interleukin-4 receptor alpha (IL-4Rα) signaling

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30 December 2023

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Macrophage Subtypes in Symptomatic Carotid Artery and Femoral Artery Plaques

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30 December 2023

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

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30 December 2023

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Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype

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30 December 2023

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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes

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30 December 2023

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Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

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FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction

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Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice.

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30 December 2023

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A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

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Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses

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30 December 2023

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Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

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30 December 2023

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

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30 December 2023

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Liver X receptor activation stimulates iron export in human alternative macrophages.

1 reference

30 December 2023

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HDL induces the expression of the M2 macrophage markers arginase 1 and Fizz-1 in a STAT6-dependent process

1 reference

30 December 2023

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Cholesteryl ester hydroperoxides increase macrophage CD36 gene expression via PPARalpha

1 reference

30 December 2023

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Phospholipase A(2)-modified LDL particles retain the generated hydrolytic products and are more atherogenic at acidic pH.

1 reference

30 December 2023

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MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages

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30 December 2023

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Phenotypic modulation of macrophages in response to plaque lipids

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30 December 2023

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Macrophage Phenotype Modulation by CXCL4 in Atherosclerosis

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30 December 2023

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Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

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Monocyte recruitment and foam cell formation in atherosclerosis

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30 December 2023

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G2A deficiency in mice promotes macrophage activation and atherosclerosis

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30 December 2023

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Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell.

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30 December 2023

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Mechanisms that regulate macrophage burden in atherosclerosis

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30 December 2023

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Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

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Molecular regulation of HDL metabolism and function: implications for novel therapies

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30 December 2023

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Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells

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30 December 2023

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Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques

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30 December 2023

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Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection.

1 reference

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Proresolution mediators and receptors: novel drug targets for enhancing pharmacological armamentarium against periodontal inflammation

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Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists

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αMβ₂ integrin activation prevents alternative activation of human and murine macrophages and impedes foam cell formation

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30 December 2023

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Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.

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30 December 2023

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TLR4 links innate immunity and fatty acid-induced insulin resistance

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Inflammation in atherosclerosis: from pathophysiology to practice

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Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells

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30 December 2023

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Macrophage activation switching: an asset for the resolution of inflammation

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30 December 2023

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Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction

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30 December 2023

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Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage

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30 December 2023

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Macrophage foam cells and atherosclerosis

1 reference

30 December 2023

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Heme and haemoglobin direct macrophage Mhem phenotype and counter foam cell formation in areas of intraplaque haemorrhage

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30 December 2023

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Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1016/J.IJCARD.2015.03.055

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1016/J.IJCARD.2015.03.055

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1016/J.IJCARD.2015.03.055

Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppel-like factor 2

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1016/J.IJCARD.2015.03.055

Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1016/J.IJCARD.2015.03.055

Identifiers

DOI

10.1016/J.IJCARD.2015.03.055

1 reference

2 September 2017

1 reference