Alcoholic liver disease: mechanisms of injury and targeted treatment (Q38381594)

2 September 2017

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title

Alcoholic liver disease: mechanisms of injury and targeted treatment (English)

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2 September 2017

main subject

alcoholic liver disease

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1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Philippe Mathurin

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Alexandre Louvet

series ordinal

1

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2 September 2017

Philippe Mathurin

series ordinal

2

1 reference

2 September 2017

language of work or name

English

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publication date

17 March 2015

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Nature Reviews Gastroenterology & Hepatology

2 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

231-242

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease

6 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Alcoholic liver disease: pathogenesis and new therapeutic targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Fibrosis progression occurs in a subgroup of heavy drinkers with typical histological features

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Five-year survival predictive factors in patients with excessive alcohol intake and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Role of variability in explaining ethanol pharmacokinetics: research and forensic applications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

ALCOHOL: its metabolism and interaction with nutrients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

CYP2E1 and oxidative liver injury by alcohol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The role of Kupffer cell oxidant production in early ethanol-induced liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Role of iron in hepatic fibrosis: one piece in the puzzle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Experimental liver cirrhosis induced by alcohol and iron

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Cell death and cell death responses in liver disease: mechanisms and clinical relevance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Decoding cell death signals in liver inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Autophagy in alcohol-induced liver diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Mitochondrial Glutathione: Importance and Transport

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

31 March 2020

12 December 2020

Mitochondrial glutathione depletion in alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Stress management: How the unfolded protein response impacts fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Endoplasmic reticulum stress in liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Alcohol and lipid metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The transcriptional and DNA binding activity of peroxisome proliferator-activated receptor alpha is inhibited by ethanol metabolism. A novel mechanism for the development of ethanol-induced fatty liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Alcohol--intoxicating roadblocks and bottlenecks in hepatic protein and lipid metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Role of AMP-activated protein kinase in mechanism of metformin action

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Cell mechanics and mechanotransduction: pathways, probes, and physiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Hepatic gene expression and lipid parameters in complement C3(-/-) mice that do not develop ethanol-induced steatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Harmful effect of adipose tissue on liver lesions in patients with alcoholic liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Excess weight risk factor for alcoholic liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Risk factors of fibrosis in alcohol-induced liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Chronic ethanol-induced insulin resistance is associated with macrophage infiltration into adipose tissue and altered expression of adipocytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Exacerbation of alcoholic liver injury by enteral endotoxin in rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Presence of plasma endotoxin is correlated with tumour necrosis factor receptor levels and disease activity in alcoholic cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Endotoxin induced hepatic necrosis in rats on an alcohol diet.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Antibiotics prevent liver injury in rats following long-term exposure to ethanol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver (disease)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

LPS induction of gene expression in human monocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Up-regulation of CD14 in liver caused by acute ethanol involves oxidant-dependent AP-1 pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Oxidative stress and signal transduction pathways in alcoholic liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Blood neutrophil functions and cytokine release in severe alcoholic hepatitis: effect of corticosteroids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A recent perspective on alcohol, immunity, and host defense.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Normal rat hepatic stellate cells respond to endotoxin in LBP-independent manner to produce inhibitor(s) of DNA synthesis in hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Interactions between the intestinal microbiome and liver diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

From stress specificity to basal necessity: ATF6 uprising. Focus on "Pancreatic β-cells depend on basal expression of active ATF6α-p50 for cell survival even under nonstress conditions".

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Alterations of the human gut microbiome in liver cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Targeting gut microbiota in obesity: effects of prebiotics and probiotics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Gut microbiota in alcoholic liver disease: pathogenetic role and therapeutic perspectives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Liver regeneration: alternative epithelial pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Interplay of hepatic and myeloid signal transducer and activator of transcription 3 in facilitating liver regeneration via tempering innate immunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Tumor necrosis factor primes hepatocytes for DNA replication in the rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Experimental methods of ethanol administration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

H9c2 cardiomyoblasts produce thyroid hormone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A histologic scoring system for prognosis of patients with alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Oncofetal gene SALL4 in aggressive hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

31 March 2020

Alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A new scoring system for prognostic stratification of patients with alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Plasma levels of soluble tumor necrosis factor receptors p55 and p75 in patients with alcoholic liver disease of increasing severity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Soluble TNF-R1, but not tumor necrosis factor alpha, predicts the 3-month mortality in patients with alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Theophylline improves steroid sensitivity in acute alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

In vitro steroid resistance correlates with outcome in severe alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Long-term outcome in patients with severe alcoholic hepatitis can be reliably determined using an in vitro measure of steroid sensitivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Glucocorticoid-induced leucine zipper: A key protein in the sensitization of monocytes to lipopolysaccharide in alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Tumour necrosis factor alpha is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Combination of steroids with infliximab or placebo in severe alcoholic hepatitis: a randomized controlled pilot study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Infliximab monotherapy for severe alcoholic hepatitis and predictors of survival: an open label trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Anti-tumor necrosis factor α treatment promotes apoptosis and prevents liver regeneration in a transgenic mouse model of chronic hepatitis C.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Corticosteroid plus pentoxifylline is not better than corticosteroid alone for improving survival in severe alcoholic hepatitis (COPE trial).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Pentoxifylline versus prednisolone for severe alcoholic hepatitis: a randomized controlled trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Pentoxifylline does not decrease short-term mortality but does reduce complications in patients with advanced cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis--a randomised clinical trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Enteral nutrition with or without N-acetylcysteine in the treatment of severe acute alcoholic hepatitis: a randomized multicenter controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Severe sepsis in cirrhosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Infection in patients with severe alcoholic hepatitis treated with steroids: early response to therapy is the key factor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Patients with acute on chronic liver failure display "sepsis-like" immune paralysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Do corticosteroids reduce mortality from alcoholic hepatitis? A meta-analysis of the randomized trials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

White cell count and platelet count associate with histological alcoholic hepatitis in jaundiced harmful drinkers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

The role of liver biopsy in the diagnosis and prognosis of patients with acute deterioration of alcoholic cirrhosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.35

Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis

31 March 2020

1 reference

12 December 2020

Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review

1 reference

12 December 2020

Colonic microbiome is altered in alcoholism.

1 reference

12 December 2020

Plasma endotoxin and serum cytokine levels in patients with alcoholic hepatitis: relation to severity of liver disturbance

1 reference

12 December 2020

Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury

1 reference

12 December 2020

Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophages

1 reference

12 December 2020

Involvement of mammalian sirtuin 1 in the action of ethanol in the liver

1 reference

12 December 2020

Chemokine levels in human liver homogenates: associations between GRO alpha and histopathological evidence of alcoholic hepatitis

1 reference

12 December 2020

Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone

1 reference

12 December 2020

Recent events in alcoholic liver disease V. effects of ethanol on liver regeneration

1 reference

12 December 2020

TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)

1 reference

12 December 2020

Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease

1 reference

12 December 2020

Iron activates NF-kappaB in Kupffer cells

1 reference

12 December 2020

Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage

1 reference

12 December 2020

Long-term ethanol feeding enhances susceptibility of the liver to orally administered lipopolysaccharides in rats

1 reference

12 December 2020

Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs

1 reference

12 December 2020

Animals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: pathophysiology, translational relevance, and challenges

1 reference

12 December 2020

Pentoxifylline suppression of tumor necrosis factor gene transcription

1 reference

12 December 2020

Long-term cannulation model for blood sampling and intragastric infusion in the rat

1 reference

12 December 2020

Recent advances in alcoholic liver disease II. Minireview: molecular mechanisms of alcoholic fatty liver

1 reference

12 December 2020

Natural history of alcoholic hepatitis. 3. Histological changes

1 reference

12 December 2020

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties andS-adenosyl-L-methionine

1 reference

12 December 2020

Contribution of the sympathetic hormone epinephrine to the sensitizing effect of ethanol on LPS-induced liver damage in mice

1 reference

12 December 2020

Corticosteroid therapy of alcoholic hepatitis

1 reference

12 December 2020

Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis

1 reference

12 December 2020

Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRGASTRO.2015.35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

1034993885

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25782093%20AND%20SRC:MED&resulttype=core&format=json