Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism (Q38391849)

2 September 2017

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism (English)

1 reference

2 September 2017

N Hagen

1

1 reference

2 September 2017

M Hans

2

1 reference

2 September 2017

D Hartmann

3

1 reference

2 September 2017

D Swandulla

4

1 reference

2 September 2017

G van Echten-Deckert

5

1 reference

2 September 2017

18 February 2011

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Cell Death & Differentiation

2 September 2017

1 reference

2 September 2017

18

1 reference

2 September 2017

1356-1365

1 reference

2 September 2017

8

1 reference

https://scigraph.springernature.com/pub.10.1038/cdd.2011.7

2 September 2017

0 references

cites work

The role of tau in neurodegeneration

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Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons

6 September 2017

1 reference

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Deregulation of sphingolipid metabolism in Alzheimer's disease

6 September 2017

1 reference

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Principles of bioactive lipid signalling: lessons from sphingolipids

6 September 2017

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Cell division in the CNS: protective response or lethal event in post-mitotic neurons?

6 September 2017

1 reference

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Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Involvement of calpain activation in neurodegenerative processes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sphingolipid metabolism in neural cells

6 September 2017

1 reference

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Essential role for sphingosine kinases in neural and vascular development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sphingosine-1-phosphate: an enigmatic signalling lipid

6 September 2017

1 reference

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Cdk5: One of the links between senile plaques and neurofibrillary tangles?

6 September 2017

1 reference

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An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

6 September 2017

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6 September 2017

1 reference

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Neurodegenerative tauopathies

6 September 2017

1 reference

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

6 September 2017

1 reference

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

6 September 2017

1 reference

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Molecular cloning and functional characterization of murine sphingosine kinase

6 September 2017

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Activation of p38 mitogen-activated protein kinase and partial reactivation of the cell cycle by cis-4-methylsphingosine direct postmitotic neurons towards apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

23 June 2018

1 reference

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Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

23 June 2018

1 reference

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The role of glycosphingolipids in neurological disorders. Mechanisms of immune action

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sequential expression of cell-cycle regulators and Alzheimer's disease-related proteins in entorhinal cortex after hippocampal excitotoxic damage.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Hyperpolarizing inhibition develops without trophic support by GABA in cultured rat midbrain neurons

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Tau in Alzheimer's disease.

31 August 2018

1 reference

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Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172106

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2011.7

cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21331079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21331079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDD.2011.7

1 reference

release_bzsq4ry7izb2pewsxs2it7dppu

2 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bzsq4ry7izb2pewsxs2it7dppu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 September 2017

1 reference