Chemoprevention against hepatocellular carcinoma (Q38550165)

4 September 2017

title

Chemoprevention against hepatocellular carcinoma (English)

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4 September 2017

Jun-Ichi Okano

1

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4 September 2017

Yuki Fujise

2

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4 September 2017

Ryo Abe

3

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4 September 2017

Ryu Imamoto

4

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4 September 2017

Yoshikazu Murawaki

5

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4 September 2017

publication date

4 June 2011

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Clinical journal of gastroenterology

4 September 2017

published in

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4 September 2017

volume

4

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4 September 2017

issue

4

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4 September 2017

page(s)

185-197

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Epidemiology of primary liver cancer

4 September 2017

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Aberrant metabolism of retinoid X receptor proteins in human hepatocellular carcinoma

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Retinoic acid receptor alpha dominant negative form causes steatohepatitis and liver tumors in transgenic mice

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Acyclic Retinoid Inhibits Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BLKS/J- +Leprdb/+Leprdb Mice

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Acyclic retinoid inhibits angiogenesis by suppressing the MAPK pathway

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Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells

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Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?

21 January 2018

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Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases

21 January 2018

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Inhibition of renin-angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats.

21 January 2018

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Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats.

21 January 2018

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The renin-angiotensin system and malignancy

21 January 2018

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Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

The enigmatic effects of caffeine in cell cycle and cancer

21 January 2018

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Coffee consumption and the risk of cancer: an overview

21 January 2018

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Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States

21 January 2018

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Coffee consumption reduces the risk of hepatocellular carcinoma independently of its aetiology: a case-control study

21 January 2018

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Coffee consumption and reduced risk of hepatocellular carcinoma among patients with chronic type C liver disease: A case-control study

21 January 2018

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Coffee consumption and reduced risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

21 January 2018

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Modulation of diethylnitrosamine carcinogenesis in rat liver and oesophagus.

21 January 2018

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Hepatocarcinogenesis inhibition by caffeine in ACI rats treated with 2-acetylaminofluorene

21 January 2018

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Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants

21 January 2018

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Caffeine enhances radiosensitization to orthotopic transplant LM3 hepatocellular carcinoma in vivo

21 January 2018

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Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity

21 January 2018

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Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway

21 January 2018

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The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver

21 January 2018

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Antiproliferation effect of commercially brewed coffees on human ovarian cancer cells in vitro

21 January 2018

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Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction

21 January 2018

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Effect of capsaicin on prostate cancer cells

21 January 2018

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Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo

21 January 2018

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Capsaicin-induced apoptosis in SK-Hep-1 hepatocarcinoma cells involves Bcl-2 downregulation and caspase-3 activation

21 January 2018

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A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells

21 January 2018

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Capsaicin: a novel chemopreventive molecule and its underlying molecular mechanisms of action

21 January 2018

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Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

21 January 2018

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Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization.

21 January 2018

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Cepharanthine exerts antitumor activity on cholangiocarcinoma by inhibiting NF-kappaB.

21 January 2018

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Cepharanthine inhibits angiogenesis and tumorigenicity of human oral squamous cell carcinoma cells by suppressing expression of vascular endothelial growth factor and interleukin-8.

21 January 2018

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Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.

21 January 2018

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Platelet Anti-Aggregation Activities of Compounds from Cinnamomum cassia

21 January 2018

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Cinnamaldehyde--a potential antidiabetic agent.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention

21 January 2018

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2'-benzoyloxycinnamaldehyde induces apoptosis in human carcinoma via reactive oxygen species

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells through activation of the proapoptotic Bcl-2 family proteins and MAPK pathway

21 January 2018

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Delayed occurrence of H-ras12V-induced hepatocellular carcinoma with long-term treatment with cinnamaldehydes

21 January 2018

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Curcumin and gemcitabine in patients with advanced pancreatic cancer

21 January 2018

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Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells

21 January 2018

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Curcumin augments gemcitabine cytotoxic effect on pancreatic adenocarcinoma cell lines.

21 January 2018

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Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis.

21 January 2018

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Suppression of altered hepatic foci development by curcumin in wistar rats

21 January 2018

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Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats

21 January 2018

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Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion

21 January 2018

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Cancer chemoprevention with garlic and its constituents

21 January 2018

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The chemistry of garlic and onions

21 January 2018

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Inhibition of aflatoxin B1- and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occurring allyl sulfides.

21 January 2018

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Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis.

21 January 2018

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Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats

21 January 2018

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Diallyl sulfide protects against N-nitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase

21 January 2018

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Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model.

21 January 2018

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n-3 PUFAs and cardiovascular disease prevention

21 January 2018

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Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.

21 January 2018

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Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice.

21 January 2018

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Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

21 January 2018

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Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice

21 January 2018

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Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line

21 January 2018

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Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2.

21 January 2018

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Tea and cancer prevention: molecular mechanisms and human relevance

21 January 2018

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Cancer prevention by tea: Evidence from laboratory studies

21 January 2018

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Green tea and tea polyphenols in cancer prevention

21 January 2018

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Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat.

21 January 2018

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Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion

21 January 2018

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Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice

21 January 2018

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Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation

21 January 2018

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A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins

21 January 2018

1 reference

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EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells

21 January 2018

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(-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis

21 January 2018

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Relationship of hepatocellular carcinoma to soya food consumption: a cohort-based, case-control study in Japan

21 January 2018

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Phytoestrogens and liver disease

21 January 2018

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A hospital-based case-control study on hepatocellular carcinoma in Fukuoka and Saga Prefectures, northern Kyushu, Japan

21 January 2018

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Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women

21 January 2018

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Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity

21 January 2018

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Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage

21 January 2018

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Anti-inflammatory effect of genistein on non-alcoholic steatohepatitis rats induced by high fat diet and its potential mechanisms.

21 January 2018

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Potential role of lycopene in the treatment of hepatitis C and prevention of hepatocellular carcinoma

21 January 2018

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beta-Carotene: an unusual type of lipid antioxidant

21 January 2018

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Tomatoes, lycopene-containing foods and cancer risk

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Antimutagenic Effects of Lycopene and Tomato Purée

21 January 2018

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Inhibitory effects of lutein and lycopene on placental glutathione S-transferase-positive preneoplastic lesions and DNA strand breakage induced in Wistar rats by the resistant hepatocyte model of hepatocarcinogenesis

21 January 2018

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Resveratrol--pills to replace a healthy diet?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis

21 January 2018

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Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Milk thistle in liver diseases: past, present, future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic cochrane hepato-biliary group review with meta-analyses of randomized clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Multitargeted therapy of cancer by silymarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Silymarin ascending multiple oral dosing phase I study in noncirrhotic patients with chronic hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Silymarin use and liver disease progression in the Hepatitis C Antiviral Long‐Term Treatment against Cirrhosis trial

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Silymarin inhibited proliferation and induced apoptosis in hepatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Effects and mechanisms of silibinin on human hepatoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Silibinin efficacy against human hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Chemopreventive effect of silymarin on liver pathology in HBV X protein transgenic mice

21 January 2018

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Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells

21 January 2018

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Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase

21 January 2018

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Multi-targeted prevention of cancer by sulforaphane

21 January 2018

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Quantitative combination effects between sulforaphane and 3,3'-diindolylmethane on proliferation of human colon cancer cells in vitro.

21 January 2018

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Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Modification of keap1 cysteine residues by sulforaphane

21 January 2018

1 reference

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Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12328-011-0227-8

Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).

21 January 2018

1 reference

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Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines.

21 January 2018

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12 December 2020

Potential synergy of phytochemicals in cancer prevention: mechanism of action

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12 December 2020

Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons

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12 December 2020

Inhibition of N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis by (-)-epigallocatechin gallate in the rat glandular stomach

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12 December 2020

Inhibition of cell proliferation and induction of apoptosis by genistein in experimental hepatocellular carcinoma

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12 December 2020

Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.

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12 December 2020

Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.

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12 December 2020

Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat

1 reference

12 December 2020

Prevention of hepatocellular carcinoma in chronic viral hepatitis patients with cirrhosis by carotenoid mixture

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12 December 2020

Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3.

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12 December 2020

Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis.

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12 December 2020

Beneficial effect of cepharanthine on overcoming drug-resistance of hepatocellular carcinoma

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12 December 2020

Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells

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12 December 2020

Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways

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12 December 2020

Eicosapentaenoic acid inhibits the growth of liver preneoplastic lesions and alters membrane phospholipid composition and peroxisomal beta-oxidation

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12 December 2020

Inhibition of human tumor growth by 2'-hydroxy- and 2'-benzoyloxycinnamaldehydes

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12 December 2020

Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats.

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12 December 2020

Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma

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12 December 2020

Garlic (Allium sativum L.) and cardiovascular diseases

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12 December 2020

Interferon alpha inhibits intrahepatic recurrence in hepatocellular carcinoma with chronic hepatitis C: a pilot study

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12 December 2020

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

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12 December 2020

Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice

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12 December 2020

Suppression of renin-angiotensin system attenuates hepatocarcinogenesis via angiogenesis inhibition in rats

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12 December 2020

Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells

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12 December 2020

Synthetic derivatives of genistein, their properties and possible applications

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12 December 2020

Induction of cell cycle arrest and apoptosis in myeloma cells by cepharanthine, a biscoclaurine alkaloid

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12 December 2020

Carotenoid action on the immune response

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12 December 2020

Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer

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12 December 2020

Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats

1 reference

12 December 2020

Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: effects on proliferation and apoptosis

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12 December 2020

Cancer chemoprevention

1 reference

12 December 2020

Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. Hepatoma Prevention Study Group

1 reference

12 December 2020

Capsaicin-induced apoptosis in human hepatoma HepG2 cells.

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12 December 2020

Potential usefulness of an EPA-enriched nutritional supplement on chemotherapy tolerability in cancer patients without overt malnutrition.

1 reference

12 December 2020

10.1007/S12328-011-0227-8

Identifiers

DOI

1 reference

Dimensions Publication ID

4 September 2017

1052266114

0 references

1 reference