The trans-sialidase, the major Trypanosoma cruzi virulence factor: Three decades of studies (Q38557287)

4 September 2017

1 reference

title

The trans-sialidase, the major Trypanosoma cruzi virulence factor: Three decades of studies (English)

1 reference

4 September 2017

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Leonardo Freire-de-Lima

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

Lúcia Mendonça Previato

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

Jose Osvaldo Previato

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

author name string

L M Fonseca

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

T Oeltmann

3

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15 June 2020

language of work or name

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29 July 2015

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4 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

15 June 2020

volume

25

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15 June 2020

issue

11

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15 June 2020

page(s)

1142-1149

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

Improving protein pharmacokinetics by genetic fusion to simple amino acid sequences

15 June 2020

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Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells

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Structural basis of sialyltransferase activity in trypanosomal sialidases

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Trans-sialidase stimulates eat me response from epithelial cells

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Mechanisms of host cell invasion by Trypanosoma cruzi

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A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence.

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The interplay between Siglecs and sialylated pathogens

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Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity.

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Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease

21 January 2018

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Chagas' disease parasite promotes neuron survival and differentiation through TrkA nerve growth factor receptor

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Neurodegeneration and neuroregeneration in Chagas disease

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The sialome--far more than the sum of its parts

21 January 2018

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A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases.

21 January 2018

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T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' disease

21 January 2018

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The Chagas' disease parasite Trypanosoma cruzi exploits nerve growth factor receptor TrkA to infect mammalian hosts

21 January 2018

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Active penetration of Trypanosoma cruzi into host cells: historical considerations and current concepts

21 January 2018

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Review on Trypanosoma cruzi: Host Cell Interaction

21 January 2018

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Serum neuraminidase activity and hematological alterations in acute human Chagas' disease

21 January 2018

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Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease.

21 January 2018

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Effects of Plasmodium berghei on thymus: high levels of apoptosis and premature egress of CD4(+)CD8(+) thymocytes in experimentally infected mice.

21 January 2018

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Trans-sialidase, SAPA amino acid repeats and the relationship between Trypanosoma cruzi and the mammalian host

21 January 2018

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Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi

21 January 2018

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Trypanosoma cruzi subverts host cell sialylation and may compromise antigen-specific CD8+ T cell responses

21 January 2018

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Trypanosoma cruzi trans-sialidase potentiates T cell activation through antigen-presenting cells: role of IL-6 and Bruton's tyrosine kinase

21 January 2018

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The Trypanosoma cruzi trans-sialidase is a T cell-independent B cell mitogen and an inducer of non-specific Ig secretion

21 January 2018

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Sialidase-based anti-influenza virus therapy protects against secondary pneumococcal infection

21 January 2018

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Characterization of Vibrio cholerae neuraminidase by a novel mechanism-based fluorescent labeling reagent

21 January 2018

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Galectin-3 silencing inhibits epirubicin-induced ATP binding cassette transporters and activates the mitochondrial apoptosis pathway via β-catenin/GSK-3β modulation in colorectal carcinoma

21 January 2018

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Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones

21 January 2018

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Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines

21 January 2018

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Addition of α-O-GlcNAc to threonine residues define the post-translational modification of mucin-like molecules in Trypanosoma cruzi.

21 January 2018

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Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding

21 January 2018

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Dynamics of Lymphocyte Populations during Trypanosoma cruzi Infection: From Thymocyte Depletion to Differential Cell Expansion/Contraction in Peripheral Lymphoid Organs.

21 January 2018

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Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex

21 January 2018

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A sexual dimorphism in intrathymic sialylation survey is revealed by the trans-sialidase from Trypanosoma cruzi

21 January 2018

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The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation

21 January 2018

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Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation

21 January 2018

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21 January 2018

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α2-3 Sialic acid glycoconjugate loss and its effect on infection with Toxoplasma parasites

21 January 2018

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Alteration of cell surface sialylation regulates antigen-induced naive CD8+ T cell responses

21 January 2018

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A sialidase mutant displaying trans-sialidase activity

21 January 2018

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A Developmentally Regulated Neuraminidase Activity in Trypanosoma cruzi

21 January 2018

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Lectin receptors as markers for Trypanosoma cruzi. Developmental stages and a study of the interaction of wheat germ agglutinin with sialic acid residues on epimastigote cells

21 January 2018

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The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin

21 January 2018

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The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis.

21 January 2018

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Temperature differences for trans-glycosylation and hydrolysis reaction reveal an acceptor binding site in the catalytic mechanism of Trypanosoma cruzi trans-sialidase

21 January 2018

1 reference

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Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages.

21 January 2018

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Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole.

21 January 2018

1 reference

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Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells

21 January 2018

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The thymus is a common target organ in infectious diseases

21 January 2018

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A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells

21 January 2018

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Enzymatically inactive trans-sialidase from Trypanosoma cruzi binds sialyl and beta-galactopyranosyl residues in a sequential ordered mechanism.

21 January 2018

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Costimulation of host T lymphocytes by a trypanosomal trans-sialidase: involvement of CD43 signaling

21 January 2018

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Galectin-8 induces apoptosis in the CD4(high)CD8(high) thymocyte subpopulation

21 January 2018

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The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents

21 January 2018

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Multifarious roles of sialic acids in immunity

21 January 2018

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Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

21 January 2018

1 reference

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Mucinases and sialidases: their role in the pathogenesis of sexually transmitted infections in the female genital tract

21 January 2018

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Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation.

21 January 2018

1 reference

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Identification of CD8 as a peanut agglutinin (PNA) receptor molecule on immature thymocytes

21 January 2018

1 reference

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Direct sialic acid transfer from a protein donor to glycolipids of trypomastigote forms of Trypanosoma cruzi.

21 January 2018

1 reference

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trans‐Sialidase fromTrypanosoma cruziInduces Apoptosis in Cells from the Immune System In Vivo

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/GLYCOB/CWV057

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json

release_dulbgeul3fbovco5mzcdttfw24

15 June 2020

Fatcat ID

1 reference

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224786%20AND%20SRC:MED&resulttype=core&format=json