Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives (Q38599131)

4 September 2017

Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives (English)

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metabolic dysfunction–associated steatotic liver disease

4 September 2017

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based on heuristic

inferred from title

non-alcoholic fatty liver

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2

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Federico Salomone

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1

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author name string

Shira Zelber-Sagi

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3

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4 September 2017

5 October 2015

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4 September 2017

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4 September 2017

36

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4 September 2017

5-20

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4 September 2017

1

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Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

4 September 2017

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Pathophysiology of NASH: perspectives for a targeted treatment

21 January 2018

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Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients

21 January 2018

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Unconjugated bilirubin, a potent endogenous antioxidant, is decreased in patients with non-alcoholic steatohepatitis and advanced fibrosis

21 January 2018

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PNPLA3 I148M polymorphism and progressive liver disease

21 January 2018

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Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence

21 January 2018

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State of the art: treatment of nonalcoholic steatohepatitis

21 January 2018

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Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

21 January 2018

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Estimated dietary intake and major food sources of polyphenols in the Polish arm of the HAPIEE study

21 January 2018

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Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells

21 January 2018

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Suppression of amphiregulin/epidermal growth factor receptor signals contributes to the protective effects of quercetin in cirrhotic rats.

21 January 2018

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Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice.

21 January 2018

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Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis

21 January 2018

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Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice

21 January 2018

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Quercetin improves hepatic fibrosis reducing hepatic stellate cells and regulating pro-fibrogenic/anti-fibrogenic molecules balance

21 January 2018

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Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats.

21 January 2018

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Rutin suppresses palmitic acids-triggered inflammation in macrophages and blocks high fat diet-induced obesity and fatty liver in mice

21 January 2018

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Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice.

21 January 2018

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Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study

21 January 2018

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Degradation of green tea catechins in tea drinks

21 January 2018

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Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation

21 January 2018

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Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet.

21 January 2018

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Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.

21 January 2018

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Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways.

21 January 2018

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Novel insights of dietary polyphenols and obesity

21 January 2018

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Consumption of polyphenol-rich juar tea increases endothelium-bound extracellular superoxide dismutase levels in men with metabolic syndrome: link with LDL oxidizability.

21 January 2018

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Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells

21 January 2018

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Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model

21 January 2018

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Dietary anthocyanins as nutritional therapy for nonalcoholic fatty liver disease

21 January 2018

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Red orange: experimental models and epidemiological evidence of its benefits on human health

21 January 2018

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Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells

21 January 2018

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Cyanidin-3-O-β-glucoside, a typical anthocyanin, exhibits antilipolytic effects in 3T3-L1 adipocytes during hyperglycemia: involvement of FoxO1-mediated transcription of adipose triglyceride lipase

21 January 2018

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The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway.

21 January 2018

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Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry.

21 January 2018

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Wild blueberry (Vaccinium angustifolium)-enriched diet improves dyslipidaemia and modulates the expression of genes related to lipid metabolism in obese Zucker rats.

21 January 2018

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Mulberry water extracts possess an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote lipolysis.

21 January 2018

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Moro orange juice prevents fatty liver in mice

21 January 2018

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Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress

21 January 2018

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Baicalein, a natural product, selectively activating AMPKα(2) and ameliorates metabolic disorder in diet-induced mice

21 January 2018

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Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha

21 January 2018

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Preventive role of genistein in an experimental non-alcoholic steatohepatitis model.

21 January 2018

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The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease

21 January 2018

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Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism.

21 January 2018

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Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity

21 January 2018

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Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids

21 January 2018

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Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance

21 January 2018

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Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway.

21 January 2018

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Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells

21 January 2018

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Citrus flavanones affect hepatic fatty acid oxidation in rats by acting as prooxidant agents

21 January 2018

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Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes

21 January 2018

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Gelidium elegans, an edible red seaweed, and hesperidin inhibit lipid accumulation and production of reactive oxygen species and reactive nitrogen species in 3T3-L1 and RAW264.7 cells

21 January 2018

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Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats.

21 January 2018

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Hesperetin derivative-7 inhibits PDGF-BB-induced hepatic stellate cell activation and proliferation by targeting Wnt/β-catenin pathway

21 January 2018

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Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis

21 January 2018

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Impact of lifestyle on metabolic syndrome in apparently healthy people

21 January 2018

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Factors associated with metabolic syndrome in a mediterranean population: role of caffeinated beverages

21 January 2018

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Coffee consumption and reduced risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

21 January 2018

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Coffee, alcohol and other beverages in relation to cirrhosis mortality: the Singapore Chinese Health Study

21 January 2018

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Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population

21 January 2018

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Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis

21 January 2018

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Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model.

21 January 2018

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Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

21 January 2018

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Inverse associations of total and decaffeinated coffee with liver enzyme levels in National Health and Nutrition Examination Survey 1999-2010

21 January 2018

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Coffee components and cardiovascular risk: beneficial and detrimental effects

21 January 2018

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Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins

21 January 2018

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Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease.

21 January 2018

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Coffee induces autophagy in vivo

21 January 2018

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Effect of chlorogenic acid on LPS-induced proinflammatory signaling in hepatic stellate cells

21 January 2018

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Biological effects of resveratrol

21 January 2018

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Grapes, wines, resveratrol, and heart health

21 January 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

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Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

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Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase

21 January 2018

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Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet

21 January 2018

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Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters

21 January 2018

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Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress.

21 January 2018

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Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet

21 January 2018

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Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats

21 January 2018

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Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

21 January 2018

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Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds.

21 January 2018

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Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice

21 January 2018

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Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

21 January 2018

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Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling

21 January 2018

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Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress

21 January 2018

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Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.

21 January 2018

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Silibinin ameliorates steatosis and insulin resistance during non-alcoholic fatty liver disease development partly through targeting IRS-1/PI3K/Akt pathway

21 January 2018

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Efficacy of lifestyle changes in subjects with non-alcoholic liver steatosis and metabolic syndrome may be improved with an antioxidant nutraceutical: a controlled clinical study

21 January 2018

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Dietary polyphenol intake in Europe: the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

21 January 2018

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A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease

21 January 2018

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Serum oxidative stress markers and lipidomic profile to detect NASH patients responsive to an antioxidant treatment: a pilot study

21 January 2018

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A new silybin-vitamin E-phospholipid complex improves insulin resistance and liver damage in patients with non-alcoholic fatty liver disease: preliminary observations

21 January 2018

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Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

21 January 2018

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Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop

21 January 2018

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Effects of Mediterranean diet supplemented with silybin–vitamin E–phospholipid complex in overweight patients with non-alcoholic fatty liver disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/LIV.12975

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4 September 2017

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PubMed ID

26436447