Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics (Q38610344)

4 September 2017

title

Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics (English)

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4 September 2017

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Valérie Taly

8

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author name string

Alexandre Baccouche

1

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4 September 2017

Shu Okumura

2

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4 September 2017

Rémi Sieskind

3

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4 September 2017

Elia Henry

4

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4 September 2017

Nathanaël Aubert-Kato

5

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4 September 2017

Nicolas Bredeche

6

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4 September 2017

Jean-François Bartolo

7

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4 September 2017

Yannick Rondelez

9

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4 September 2017

Teruo Fujii

10

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4 September 2017

Anthony J Genot

11

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4 September 2017

publication date

24 August 2017

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4 September 2017

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4 September 2017

volume

12

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4 September 2017

issue

9

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4 September 2017

page(s)

1912-1932

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4 September 2017

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Formation of droplets and bubbles in a microfluidic T-junction-scaling and mechanism of break-up

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Reactions in droplets in microfluidic channels

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Microfluidic flow focusing: drop size and scaling in pressure versus flow-rate-driven pumping

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Droplets as microreactors for high-throughput biology

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Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme.

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Microfluidics using spatially defined arrays of droplets in one, two, and three dimensions

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Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients.

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Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets

21 January 2018

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High-resolution mapping of bifurcations in nonlinear biochemical circuits.

21 January 2018

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Loop-mediated isothermal amplification of DNA

21 January 2018

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21 January 2018

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The original Michaelis constant: translation of the 1913 Michaelis-Menten paper

21 January 2018

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Screening for enzyme inhibitors by surface plasmon resonance combined with mass spectrometry.

21 January 2018

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Protein detection using proximity-dependent DNA ligation assays.

21 January 2018

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A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates

21 January 2018

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A malachite green colorimetric assay for protein phosphatase activity

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Enzymatic assembly of DNA molecules up to several hundred kilobases

21 January 2018

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Ultrahigh-throughput-directed enzyme evolution by absorbance-activated droplet sorting (AADS).

21 January 2018

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Droplet-based microfluidics for dose-response assay of enzyme inhibitors by electrochemical method.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Rapid droplet mixers for digital microfluidic systems

21 January 2018

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Pillar-induced droplet merging in microfluidic circuits.

21 January 2018

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Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assays

21 January 2018

1 reference

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Controlling molecular transport in minimal emulsions

21 January 2018

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Applying microdroplets as sensors for label-free detection of chemical reactions.

21 January 2018

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Soft lithography for micro- and nanoscale patterning

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Single-cell analysis and sorting using droplet-based microfluidics

21 January 2018

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Modification of the glass surface property in PDMS-glass hybrid microfluidic devices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Surfactants in droplet-based microfluidics

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Biocompatible surfactants for water-in-fluorocarbon emulsions.

21 January 2018

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Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity.

21 January 2018

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Dropspots: a picoliter array in a microfluidic device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Real time quantitative PCR

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPROT.2017.092

Distilling free-form natural laws from experimental data

21 January 2018

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Robots that can adapt like animals.

21 January 2018

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A fast and elitist multiobjective genetic algorithm: NSGA-II

21 January 2018

1 reference

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Hands-off preparation of monodisperse emulsion droplets using a poly(dimethylsiloxane) microfluidic chip for droplet digital PCR.

21 January 2018

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Assessment of surfactants for efficient droplet PCR in mineral oil using the pendant drop technique.

21 January 2018

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Droplets and Bubbles in Microfluidic Devices

21 January 2018

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Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device

21 January 2018

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High-throughput and long-term observation of compartmentalized biochemical oscillators

21 January 2018

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Generation of monodisperse cell-sized microdroplets using a centrifuge-based axisymmetric co-flowing microfluidic device

21 January 2018

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Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays

31 March 2020

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Enzyme kinetic measurements using a droplet-based microfluidic system with a concentration gradient

31 March 2020

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Automated microfluidic screening assay platform based on DropLab

31 March 2020

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Flat field correction for high-throughput imaging of fluorescent samples

31 March 2020

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PCR digitale en micro-compartiments

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28837132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biochemical titration of glycogen in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28837132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPROT.2017.092

1 reference

Dimensions Publication ID

4 September 2017

1091326408

0 references

1 reference