Matrix Metalloproteinase in Blood-Brain Barrier Breakdown in Dementia (Q38645205)

5 September 2017

Matrix Metalloproteinase in Blood-Brain Barrier Breakdown in Dementia (English)

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5 September 2017

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Erica M Weekman

1

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PubMed ID

26599057

5 September 2017

Donna M Wilcock

series ordinal

2

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5 September 2017

21 November 2015

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Journal of Alzheimer's Disease

5 September 2017

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5 September 2017

49

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5 September 2017

4

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5 September 2017

893-903

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Physiology and pathophysiology of matrix metalloproteases.

5 September 2017

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https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Targeting MMPs in acute and chronic neurological conditions

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Role of matrix metalloproteinases in delayed cortical responses after stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Strategies for MMP inhibition in cancer: innovations for the post-trial era.

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

A matrix metalloproteinase expressed on the surface of invasive tumour cells

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

The cell surface: the stage for matrix metalloproteinase regulation of migration

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Clinical factors associated with dementia in ischaemic stroke

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Dementia three months after stroke. Baseline frequency and effect of different definitions of dementia in the Helsinki Stroke Aging Memory Study (SAM) cohort.

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Dementia after stroke: Baseline frequency, risks, and clinical features in a hospitalized cohort

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Cognitive impairment after stroke: frequency, patterns, and relationship to functional abilities

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Cerebral microbleeds are regionally associated with intracerebral hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Cerebral microbleeds, retinopathy, and dementia: the AGES-Reykjavik Study

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Cerebral microbleeds are associated with worse cognitive function: the Rotterdam Scan Study

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

A new penumbra: transitioning from injury into repair after stroke

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Metalloproteinases: mediators of pathology and regeneration in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Hemorrhagic transformation of childhood arterial ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Frequency and determinants for hemorrhagic transformation of cerebral infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase activation and blood-brain barrier breakdown following thrombolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Novel situations of endothelial injury in stroke--mechanisms of stroke and strategy of drug development: intracranial bleeding associated with the treatment of ischemic stroke: thrombolytic treatment of ischemia-affected endothelial cells with tissu

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Hemorrhagic transformation after ischemic stroke in animals and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Blood-brain barrier tight junction permeability and ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Gene expression profiling of blood for the prediction of ischemic stroke

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Unriddling the role of matrix metalloproteinases in human cerebral stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Relationship between plasma metalloproteinase-9 levels and volume and severity of infarct in patients with acute ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Mechanical reperfusion is associated with post-ischemic hemorrhage in rat brain

21 January 2018

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https://api.crossref.org/works/10.3233%2FJAD-150759

Reperfusion activates metalloproteinases that contribute to neurovascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases increase very early during experimental focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Xanthine oxidase activates pro-matrix metalloproteinase-2 in cultured rat vascular smooth muscle cells through non-free radical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Blood-brain barrier breakdown in acute and chronic cerebrovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 and myeloperoxidase expression: quantitative analysis by antigen immunohistochemistry in a model of transient focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Vascular MMP-9/TIMP-2 and neuronal MMP-10 up-regulation in human brain after stroke: a combined laser microdissection and protein array study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

A broad-spectrum matrix metalloproteinase inhibitor prevents hemorrhagic complications induced by tissue plasminogen activator in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 potentiates early brain injury after subarachnoid hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Induction of mmp-9 expression and endothelial injury by oxidative stress after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 concentration after spontaneous intracerebral hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Time course of upregulation of inflammatory mediators in the hemorrhagic brain in rats: correlation with brain edema

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Mechanisms of edema formation after intracerebral hemorrhage: effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Role of blood clot formation on early edema development after experimental intracerebral hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Brain pericytes are the most thrombin-sensitive matrix metalloproteinase-9-releasing cell type constituting the blood-brain barrier in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Dexamethasone inhibits ICAM-1 and MMP-9 expression and reduces brain edema in intracerebral hemorrhagic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Alzheimer disease and cerebrovascular pathology: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Lobar brain hemorrhages and white matter changes: Clinical, radiological and laboratorial profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

MMP-2/MMP-9 plasma level and brain expression in cerebral amyloid angiopathy-associated hemorrhagic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Diagnosis of cerebral amyloid angiopathy. Sensitivity and specificity of cortical biopsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Soluble aggregates of the amyloid-beta protein selectively stimulate permeability in human brain microvascular endothelial monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Matrix metalloproteinase-9 in cerebral-amyloid-angiopathy-related hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Cerebral amyloid angiopathy: progressive disruption of the neurovascular unit

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Innate immunity in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Amyloid-beta (25-35) peptide induces the release of pro-matrix metalloprotease 9 (pro-MMP-9) from human neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Limited cleavage of tau with matrix-metalloproteinase MMP-9, but not MMP-3, enhances tau oligomer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Propagation of tau misfolding from the outside to the inside of a cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Amyloid beta-induced nerve growth factor dysmetabolism in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

Increased matrix metalloproteinase 9 activity in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-150759

21 January 2018

Identifiers

DOI

10.3233/JAD-150759

1 reference

5 September 2017

1 reference

PubMed ID

26599057