Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities (Q38648767)

http://europepmc.org/abstract/PMC/6332387

1 July 2019

1 reference

7 November 2019

Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities (English)

1 reference

http://europepmc.org/abstract/PMC/6332387

1 July 2019

1 reference

7 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Krystian Marszałek

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Sylwia Skąpska

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

19 November 2015

2 references

http://europepmc.org/abstract/PMC/6332387

1 July 2019

7 November 2019

2 references

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

20614-20641

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

8 June 2020

copyright license

1 reference

7 November 2019

Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antimicrobial activity of oleanolic and ursolic acids: an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Oleanolic acid and ursolic acid: research perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Pharmacology of oleanolic acid and ursolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Fruit cuticular waxes as a source of biologically active triterpenoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Polyisoprenoids: structure, biosynthesis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Biogenesis, molecular regulation and function of plant isoprenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Triterpene biosynthesis in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis by suppressing the expression of FoxM1 in MCF-7 human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

The cytotoxic activity of ursolic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

In vitro and in vivo anticancer activity evaluation of ursolic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and suppression of ERK1/2 MAPK in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Enhancement of chemotherapeutic agent-induced apoptosis by inhibition of NF-kappaB using ursolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid and its natural derivative corosolic acid suppress the proliferation of APC-mutated colon cancer cells through promotion of β-catenin degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis of SW480 cells via p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Sensitization of ionizing radiation-induced apoptosis by ursolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Synthesis and evaluation of ursolic acid derivatives as potent cytotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits the invasive phenotype of SNU-484 human gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Delivery of ursolic acid (UA) in polymeric nanoparticles effectively promotes the apoptosis of gastric cancer cells through enhanced inhibition of cyclooxygenase 2 (COX-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Endogenous reverse transcriptase as a mediator of ursolic acid's anti-proliferative and differentiating effects in human cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibition of HepG2 cell proliferation by ursolic acid and polysaccharides via the downregulation of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Oleanolic acid and ursolic acid induce apoptosis in HuH7 human hepatocellular carcinoma cells through a mitochondrial-dependent pathway and downregulation of XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antiangiogenic potential of three triterpenic acids in human liver cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antiangiogenic activity of ursolic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ezrin dephosphorylation/downregulation contributes to ursolic acid-mediated cell death in human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces HL60 monocytic differentiation and upregulates C/EBPβ expression by ERK pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibition of cell proliferation, invasion and migration by ursolic acid in human lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits epithelial-mesenchymal transition by suppressing the expression of astrocyte-elevated gene-1 in human nonsmall cell lung cancer A549 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Effects of ursolic acid on the proliferation and apoptosis of human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Synthesis of novel ursolic acid heterocyclic derivatives with improved abilities of antiproliferation and induction of p53, p21waf1 and NOXA in pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-induced Bcl-2 phosphorylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Anti-inflammatory effects of 27 selected terpenoid compounds tested through modulating Th1/Th2 cytokine secretion profiles using murine primary splenocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid, a potential PPARγ agonist, suppresses ovalbumin-induced airway inflammation and Penh by down-regulating IL-5, IL-13, and IL-17 in a mouse model of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits nuclear factor-κB signaling in intestinal epithelial cells and macrophages, and attenuates experimental colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antioxidative and anti-inflammatory protection of oleanolic acid and ursolic acid in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Topical anti-inflammatory activity of Salvia officinalis L. leaves: the relevance of ursolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Amelioration of adjuvant-induced arthritis by ursolic acid through altered Th1/Th2 cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Protective effects of ursolic acid and luteolin against oxidative DNA damage include enhancement of DNA repair in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid and oleanolic acid suppress preneoplastic lesions induced by 1,2-dimethylhydrazine in rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits cigarette smoke extract-induced human bronchial epithelial cell injury and prevents development of lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation; ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant, Glechoma hederaceae L.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antitumor activity of compounds isolated from leaves of Eriobotrya japonica

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibitory effects of ursolic and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Introduction to NF-kappaB: players, pathways, perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Forkhead box M1 transcription factor: a novel target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

BCL-2 family: regulators of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Review: nuclear events in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

The inhibitor of apoptosis protein family (IAPs): an emerging therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibition of endogenous reverse transcriptase antagonizes human tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Effects of ursolic acid on different steps of the angiogenic process

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

21 January 2018

Cyclooxygenases 1 and 2

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

A phase I trial to evaluate the multiple-dose safety and antitumor activity of ursolic acid liposomes in subjects with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid enhances mouse liver regeneration after partial hepatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Fruit and vegetables, and cardiovascular disease: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Protective effect of ursolic Acid against myocardial ischemia induced by isoproterenol in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Effect of ursolic acid on cardiac marker enzymes, lipid profile and macroscopic enzyme mapping assay in isoproterenol-induced myocardial ischemic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid inhibits neointima formation in the rat carotid artery injury model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid suppresses IL-6 induced C-reactive protein expression in HepG2 and protects HUVECs from injury induced by CRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Enhancement of platelet aggregation by ursolic Acid and oleanolic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

The relationship between excitotoxicity and oxidative stress in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid attenuates lipopolysaccharide-induced cognitive deficits in mouse brain through suppressing p38/NF-κB mediated inflammatory pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid improves domoic acid-induced cognitive deficits in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Anxiolytic-like effects of ursolic acid in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Novel intriguing strategies attenuating to sarcopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid ameliorates aging-metabolic phenotype through promoting of skeletal muscle rejuvenation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Cellular and molecular mechanisms of bone remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Anabolic activity of ursolic acid in bone: Stimulating osteoblast differentiation in vitro and inducing new bone formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Tryptophan hydroxylase 1 (Tph-1)-targeted bone anabolic agents for osteoporosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Nephroprotective role of resveratrol and ursolic Acid in aristolochic Acid intoxicated zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Nephroprotective effect of ursolic Acid in a murine model of gentamicin-induced renal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Evaluation of the antibacterial activity of the methylene chloride extract of Miconia ligustroides, isolated triterpene acids, and ursolic acid derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antimicrobial activity of some pentacyclic triterpenes and their synthesized 3-O-lipophilic chains

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid improves survival and attenuates lung injury in septic rats induced by cecal ligation and puncture

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Oleanolic acid and ursolic acid affect peptidoglycan metabolism in Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Secondary metabolites from Chamaedora tepejilote (Palmae) are active against Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antimicrobial Effect of Ursolic Acid and Oleanolic Acid against Methicillin-Resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibition of Streptococcus mutans biofilm formation on composite resins containing ursolic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Effects of plant extracts on HIV-1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Inhibitory effects of constituents from Cynomorium songaricum and related triterpene derivatives on HIV-1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Triterpenes as potential dimerization inhibitors of HIV-1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Oleanolic acid and ursolic acid: novel hepatitis C virus antivirals that inhibit NS5B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Supercritical fluid extraction of heather (Calluna vulgaris) and evaluation of anti-hepatitis C virus activity of the extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Anti-herpes virus activities of bioactive fraction and isolated pure constituent of Mallotus peltatus: an ethnomedicine from Andaman Islands.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

In vivo activity of ursolic and oleanolic acids during the acute phase of Trypanosoma cruzi infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Synthesis of isosteric triterpenoid derivatives and antifungal activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Antifilarial effect of ursolic acid from Nyctanthes arbortristis: molecular and biochemical evidences

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Treatment with triterpenic fraction purified from Baccharis uncinella leaves inhibits Leishmania (Leishmania) amazonensis spreading and improves Th1 immune response in infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Bioassay-Guided Isolation of Antimalarial Triterpenoid Acids from the Leaves ofMorinda lucida

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES201119721

Ursolic acid isolated from Eucalyptus tereticornis protects against ethanol toxicity in isolated rat hepatocytes

21 January 2018

1 reference

12 December 2020

Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells

1 reference

12 December 2020

Ursolic acid triggers calcium-dependent apoptosis in human Daudi cells

1 reference

12 December 2020

Liposome-encapsulated ursolic acid increases ceramides and collagen in human skin cells.

1 reference

12 December 2020

Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview

1 reference

12 December 2020

Anti-hepatoma activity and mechanism of ursolic acid and its derivatives isolated from Aralia decaisneana

1 reference

12 December 2020

Impact of ursolic acid on chronic ethanol-induced oxidative stress in the rat heart.

1 reference

12 December 2020

Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta

1 reference

12 December 2020

Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity.

1 reference

12 December 2020

Pharmacological activities of natural triterpenoids and their therapeutic implications.

1 reference

12 December 2020

Biologically Active constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells

1 reference

12 December 2020

Up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis.

1 reference

12 December 2020

Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity

1 reference

12 December 2020

Ursolic acid, a naturally occurring triterpenoid, demonstrates anticancer activity on human prostate cancer cells

1 reference

12 December 2020

Antimicrobial activity of oleanolic acid from Salvia officinalis and related compounds on vancomycin-resistant enterococci (VRE)

1 reference

12 December 2020

Antihistaminic and antieicosanoid effects of oleanolic and ursolic acid fraction from Helichrysum picardii

1 reference

12 December 2020

Protective effect of oleanolic acid and ursolic acid against lipid peroxidation

1 reference

12 December 2020

Differential involvement of mitochondria during ursolic acid-induced apoptotic process in HaCaT and M4Beu cells

1 reference

12 December 2020

Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats

1 reference

12 December 2020

Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica

1 reference

12 December 2020

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

1 reference

12 December 2020

Uncoupling and Antioxidant Effects of Ursolic Acid in Isolated Rat Heart Mitochondria

1 reference

12 December 2020

Ursolic acid causes DNA-damage, p53-mediated, mitochondria- and caspase-dependent human endothelial cell apoptosis, and accelerates atherosclerotic plaque formation in vivo

1 reference

12 December 2020

Ursolic acid effect on atherosclerosis: apples and apples, or apples and oranges?

1 reference

12 December 2020

Ursolic acid inhibits T-cell activation through modulating nuclear factor-κ B signaling

1 reference

12 December 2020

The effect of ursolic and oleanolic acids on human skin fibroblast cells.

1 reference

12 December 2020

Modulation of antibiotic resistance in bacterial pathogens by oleanolic acid and ursolic acid

1 reference

12 December 2020

Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway

1 reference

12 December 2020

Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways

1 reference

12 December 2020

Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies

1 reference

12 December 2020

Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: Evidence for the involvement of the dopaminergic system

1 reference

12 December 2020

Evaluation of toxicity and single-dose pharmacokinetics of intravenous ursolic acid liposomes in healthy adult volunteers and patients with advanced solid tumors

1 reference

12 December 2020

Ursolic acid attenuates lipopolysaccharide-induced acute lung injury in a mouse model

1 reference

12 December 2020

A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors

1 reference

12 December 2020

Inhibitory effects of the leaves of loquat (Eriobotrya japonica) on bone mineral density loss in ovariectomized mice and osteoclast differentiation

1 reference

12 December 2020

Antibacterial and antioxidant activities of ursolic acid and derivatives

1 reference

12 December 2020

Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice

1 reference

12 December 2020

Effect of ursolic acid and Rosiglitazone combination on hepatic lipid accumulation in high fat diet-fed C57BL/6J mice

1 reference

12 December 2020

Ursolic acid derivative ameliorates streptozotocin-induced diabestic bone deleterious effects in mice

1 reference

12 December 2020

Inhibition of glucosyltransferase from Streptococcus mutans by oleanolic acid and ursolic acid

1 reference

12 December 2020

Investigations on the steroidal anti-inflammatory activity of triterpenoids from Diospyros leucomelas

1 reference

12 December 2020

Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

1 reference

12 December 2020

Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells

1 reference

12 December 2020

Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice

1 reference

12 December 2020

Intracellular Ca2+ release mediates ursolic acid-induced apoptosis in human leukemic HL-60 cells

1 reference

12 December 2020

Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis

1 reference

12 December 2020

10.3390/MOLECULES201119721

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

26610440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26610440%20AND%20SRC:MED&resulttype=core&format=json