The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi (Q38684227)

5 September 2017

The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi (English)

1 reference

5 September 2017

0 references

reactive oxygen species

1 reference

Marcia Cristina Paes

1

1 reference

5 September 2017

Daniela Cosentino-Gomes

2

1 reference

5 September 2017

Cíntia Fernandes de Souza

3

1 reference

5 September 2017

Natália Pereira de Almeida Nogueira

4

1 reference

5 September 2017

José Roberto Meyer-Fernandes

5

1 reference

5 September 2017

language of work or name

1 reference

9 October 2011

1 reference

Journal of parasitology research

5 September 2017

1 reference

5 September 2017

2011

1 reference

5 September 2017

174614

1 reference

Creative Commons Attribution 3.0 Unported

5 September 2017

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

Creative Commons Attribution 3.0 Unported

0 references

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivity

6 September 2017

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A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI.

6 September 2017

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The trypanocidal activity of naphthoquinones: a review

6 September 2017

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Fighting the oxidative assault: the Trypanosoma cruzi journey to infection

6 September 2017

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Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence

6 September 2017

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Mitochondria and reactive oxygen species

6 September 2017

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Particularities of mitochondrial structure in parasitic protists (Apicomplexa and Kinetoplastida).

6 September 2017

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A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis

6 September 2017

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Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

6 September 2017

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Proteomic analysis of Trypanosoma cruzi resistance to Benznidazole

6 September 2017

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Revisiting heme mechanisms. A perspective on the mechanisms of nitric oxide synthase (NOS), Heme oxygenase (HO), and cytochrome P450s (CYP450s).

6 September 2017

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Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

6 September 2017

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Proteomic analysis of metacyclic trypomastigotes undergoing Trypanosoma cruzi metacyclogenesis.

6 September 2017

1 reference

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Exploring the role of insect host factors in the dynamics of Trypanosoma cruzi-Rhodnius prolixus interactions

6 September 2017

1 reference

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Adaptations against heme toxicity in blood-feeding arthropods

6 September 2017

1 reference

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Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi

6 September 2017

1 reference

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DNA metabolism and genetic diversity in Trypanosomes

6 September 2017

1 reference

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The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

6 September 2017

1 reference

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Oxidative stress and antioxidant defenses: a target for the treatment of diseases caused by parasitic protozoa

6 September 2017

1 reference

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Chemotherapy with benznidazole and itraconazole for mice infected with different Trypanosoma cruzi clonal genotypes

6 September 2017

1 reference

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Molecular cloning and expression of the catalytic subunit of protein kinase A from Trypanosoma cruzi

6 September 2017

1 reference

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Trypanosomal antioxidants and emerging aspects of redox regulation in the trypanosomatids

6 September 2017

1 reference

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Basic cell biology of Trypanosoma cruzi

6 September 2017

1 reference

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The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties

6 September 2017

1 reference

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Trypanosoma cruzi epimastigote endocytic pathway: cargo enters the cytostome and passes through an early endosomal network before storage in reservosomes

6 September 2017

1 reference

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Pathways involved in environmental sensing in trypanosomatids.

6 September 2017

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Cyclic AMP signaling in trypanosomatids

6 September 2017

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6 September 2017

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Growth of Trypanosoma cruzi in a cloned macrophage cell line and in a variant defective in oxygen metabolism

6 September 2017

1 reference

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"Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease

6 September 2017

1 reference

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Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock

6 September 2017

1 reference

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Deletion of the Trypanosoma brucei superoxide dismutase gene sodb1 increases sensitivity to nifurtimox and benznidazole.

6 September 2017

1 reference

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A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania

6 September 2017

1 reference

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Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Molecular cloning and characterization of the protein kinase A regulatory subunit of Trypanosoma cruzi

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Macrophage-derived peroxynitrite diffusion and toxicity to Trypanosoma cruzi

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Trypanosoma cruzi: Ultrastructural, cytochemical and freeze-fracture studies of protein uptake

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Stage-specific substrate phosphorylation by a Ca2+/calmodulin-dependent protein kinase in Trypanosoma cruzi

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Role of glutathione in the susceptibility of Trypanosoma cruzi to drugs.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Mode of action of nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Heme-induced Trypanosoma cruzi proliferation is mediated by CaM kinase II.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Modulation of Trypanosoma rangeli ecto-phosphatase activity by hydrogen peroxide.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Trypanosoma cruzi: in vitro activity of Epoxy-alpha-Lap, a derivative of alpha-lapachone, on trypomastigote and amastigote forms

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Antiproliferative effect of sera from chagasic patients on Trypanosoma cruzi epimastigotes. Involvement of xanthine oxidase.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Mitochondrial calcium overload triggers complement-dependent superoxide-mediated programmed cell death in Trypanosoma cruzi

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Molecular characterization of cytosolic and mitochondrial tryparedoxin peroxidase in Trypanosoma cruzi populations susceptible and resistant to benznidazole

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Differential gene expression in Trypanosoma cruzi populations susceptible and resistant to benznidazole

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Resistance to oxidative stress is associated with metastasis in mucocutaneous leishmaniasis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

The glucose-6-phosphate dehydrogenase from Trypanosoma cruzi: its role in the defense of the parasite against oxidative stress

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Lack of correlation between in vitro susceptibility to Benznidazole and phylogenetic diversity of Trypanosoma cruzi, the agent of Chagas disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Identification of free radicals on hemoglobin from its self-peroxidation using mass spectrometry and immuno-spin trapping: observation of a histidinyl radical

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Cytotoxicity of beta-lapachone, an naphthoquinone with possible therapeutic use

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Characterization of the Trypanosoma cruzi Cdc2p-related protein kinase 1 and identification of three novel associating cyclins

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Inducible resistance to oxidant stress in the protozoan Leishmania chagasi.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3191734

Nova tripanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., n. sp., ajente etiolojico de nova entidade morbida do homem

31 August 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F174614

Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F174614

Glutathione and trypanothione in several strains of Trypanosoma cruzi: Effect of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F174614

Effects of Nifurtimox and benznidazole upon glutathione and trypanothione content in epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F174614

Trypanosoma cruzi-mediated IFN-gamma-inducible nitric oxide output in macrophages is regulated by iNOS mRNA stability

21 January 2018

1 reference

12 December 2020

Trypanosoma cruzi: Oxidative stress induces arginine kinase expression

1 reference

12 December 2020

Leishmania amazonensis: heme stimulates (Na(+)+K(+))ATPase activity via phosphatidylinositol-specific phospholipase C/protein kinase C-like (PI-PLC/PKC) signaling pathways

1 reference

12 December 2020

Effects of nifurtimox and benznidazole upon glutathione and trypanothione content in epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi

1 reference

12 December 2020

Evolution of the haem synthetic pathway in kinetoplastid flagellates: an essential pathway that is not essential after all?

1 reference

12 December 2020

Hemin-induced lipid membrane disorder and increased permeability: a molecular model for the mechanism of cell lysis

1 reference

12 December 2020

Biochemical and immunological studies of protein kinase C from Trypanosoma cruzi

1 reference

12 December 2020

The heme uptake process in Trypanosoma cruzi epimastigotes is inhibited by heme analogues and by inhibitors of ABC transporters

1 reference

12 December 2020

Characterization of the catalytic subunit of Trypanosoma cruzi cyclic AMP-dependent protein kinase

1 reference

12 December 2020

Phospholipid signalling pathways in Trypanosoma cruzi growth control

1 reference

12 December 2020

The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/174614

1 reference

5 September 2017

1 reference

5 September 2017

PubMed publication ID

22007287

1 reference