STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling. (Q38717767)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28165510%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling (English)

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1 April 2020

7

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1 April 2020

Zhi Li

10

1 reference

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1 April 2020

Sandra Pellegrini

12

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1 April 2020

author name string

Kei-Ichiro Arimoto

1

1 reference

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1 April 2020

Sara Löchte

2

1 reference

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1 April 2020

Samuel A Stoner

3

1 reference

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1 April 2020

Christoph Burkart

4

1 reference

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1 April 2020

Yue Zhang

5

1 reference

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1 April 2020

Sayuri Miyauchi

6

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1 April 2020

Jun-Bao Fan

8

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1 April 2020

Jürgen J Heinisch

9

1 reference

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1 April 2020

Ming Yan

11

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1 April 2020

Frédéric Colland

13

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1 April 2020

Jacob Piehler

14

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1 April 2020

Dong-Er Zhang

15

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1 April 2020

publication date

6 February 2017

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Nature Structural & Molecular Biology

1 April 2020

published in

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1 April 2020

volume

24

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1 April 2020

issue

3

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1 April 2020

page(s)

279-289

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describes a project that uses

1 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5365074/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nsmb.3378

0 references

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6 September 2017

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Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes

6 September 2017

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6 September 2017

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Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway

6 September 2017

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6 September 2017

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Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10

6 September 2017

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STAT2 deficiency and susceptibility to viral illness in humans

6 September 2017

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Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions

6 September 2017

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Immunomodulatory functions of type I interferons

6 September 2017

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Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor

6 September 2017

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USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

6 September 2017

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Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells

6 September 2017

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6 September 2017

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Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

6 September 2017

1 reference

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Conversion of red fluorescent protein into a bright blue probe

6 September 2017

1 reference

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A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

6 September 2017

1 reference

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Interferons at age 50: past, current and future impact on biomedicine

6 September 2017

1 reference

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SOCS proteins, cytokine signalling and immune regulation

6 September 2017

1 reference

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Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

6 September 2017

1 reference

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Complex modulation of cell type-specific signaling in response to type I interferons

6 September 2017

1 reference

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UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

6 September 2017

1 reference

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Identification of GAS-dependent interferon-sensitive target genes whose transcription is STAT2-dependent but ISGF3-independent

6 September 2017

1 reference

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Mechanisms of type-I- and type-II-interferon-mediated signalling

6 September 2017

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Interferon-alpha: a clinical update.

6 September 2017

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FRAP analysis of binding: proper and fitting

6 September 2017

1 reference

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Functional relevance of the conserved DNA-binding domain of STAT2.

6 September 2017

1 reference

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Functional proteomics mapping of a human signaling pathway

6 September 2017

1 reference

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Analysis of binding reactions by fluorescence recovery after photobleaching

6 September 2017

1 reference

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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

6 September 2017

1 reference

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Stats: transcriptional control and biological impact

6 September 2017

1 reference

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Dysregulation of protein modification by ISG15 results in brain cell injury

6 September 2017

1 reference

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UBP43 (USP18) specifically removes ISG15 from conjugated proteins

6 September 2017

1 reference

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Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

6 September 2017

1 reference

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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

The linker domain of Stat1 is required for gamma interferon-driven transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Side effects of alpha interferon in chronic hepatitis C.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Alpha and beta interferons and their receptor and their friends and relations.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Role of STAT2 in the alpha interferon signaling pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

ISG15 uncut: Dissecting enzymatic and non-enzymatic functions of USP18 in vivo

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Functional immobilization and patterning of proteins by an enzymatic transfer reaction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Critical role for constitutive type I interferon signaling in the prevention of cellular transformation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

RGD-grafted poly-L-lysine-graft-(polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5365074

Aicardi–Goutières syndrome

31 August 2018

1 reference

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

21 January 2018

1 reference

Characterization of Antihuman IFNAR-1 Monoclonal Antibodies: Epitope Localization and Functional Analysis

21 January 2018

1 reference

Immune response in Stat2 knockout mice

21 January 2018

1 reference

Spatial organization of lipid phases in micropatterned polymer-supported membranes

31 March 2020

1 reference

Spatiotemporally Controlled Reorganization of Signaling Complexes in the Plasma Membrane of Living Cells

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.3378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28165510%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28165510%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference