Expanding roles of the hypoxia-response network in chronic kidney disease (Q38726764)

5 September 2017

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title

Expanding roles of the hypoxia-response network in chronic kidney disease (English)

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5 September 2017

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Tetsuhiro Tanaka

1

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5 September 2017

9 February 2016

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Clinical and experimental nephrology

5 September 2017

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5 September 2017

20

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5 September 2017

835-844

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5 September 2017

6

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https://scigraph.springernature.com/pub.10.1007/s10157-016-1241-4

5 September 2017

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cites work

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia-induced apoptosis in cultured glomerular endothelial cells: involvement of mitochondrial pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Transdifferentiation of cultured tubular cells induced by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Evidence of tubular hypoxia in the early phase in the remnant kidney model

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Renal oxygenation defects in the spontaneously hypertensive rat: role of AT1 receptors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Angiotensin-induced defects in renal oxygenation: role of oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Oxygen sensing by HIF hydroxylases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Sites of erythropoietin production

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

A mouse model of adult-onset anaemia due to erythropoietin deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Regulation of hypoxia-inducible factor in kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

HIF activation protects from acute kidney injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Mechanisms of disease: Cell death in acute renal failure and emerging evidence for a protective role of erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Kidney injury is independent of endothelial HIF-1α.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

A genetic variant of hypoxia-inducible factor-1alpha is associated with adverse outcomes in acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia in renal disease with proteinuria and/or glomerular hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Adaptation to hypoxia in the diabetic rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Cortical microvascular remodeling in the stenotic kidney: role of increased oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Adipose tissue-derived mesenchymal stem cells in long-term dialysis patients display downregulation of PCAF expression and poor angiogenesis activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Activation of hypoxia-inducible factors prevents diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Origin and function of myofibroblasts in kidney fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

The contribution of epithelial-mesenchymal transition to renal fibrosis differs among kidney disease models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Up-regulation of glycolytic metabolism is required for HIF1α-driven bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10157-016-1241-4

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

21 January 2018

1 reference

12 December 2020

Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine

1 reference

12 December 2020

Nephron pO2 and renal oxygen usage in the hypertensive rat kidney

1 reference

12 December 2020

The obliteration of the postglomerular capillaries and its influence upon the function of both glomeruli and tubuli. Functional interpretation of morphologic findings

1 reference

12 December 2020

Role of the microvascular endothelium in progressive renal disease.

1 reference

12 December 2020

Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia

1 reference

12 December 2020

Change of paradigms in nephrology--a view back and a look forward

1 reference

12 December 2020

Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI

1 reference

12 December 2020

10.1007/S10157-016-1241-4

Identifiers

DOI

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5 September 2017

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PubMed ID

26857707