Metabolic Control of Plasma Cell Differentiation- What We Know and What We Don't Know (Q38748145)

6 September 2017

title

Metabolic Control of Plasma Cell Differentiation- What We Know and What We Don't Know (English)

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6 September 2017

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Michael Aronov

1

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6 September 2017

Boaz Tirosh

series ordinal

2

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6 September 2017

publication date

24 February 2016

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Journal of Clinical Immunology

6 September 2017

published in

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6 September 2017

volume

36 Suppl 1

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6 September 2017

page(s)

12-17

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Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

The genetic network controlling plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Lipid-dependent regulation of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

On the redox control of B lymphocyte differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

B- to plasma-cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

High XBP1 expression is a marker of better outcome in multiple myeloma patients treated with bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Plasma cells require autophagy for sustainable immunoglobulin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Making new contacts: the mTOR network in metabolism and signalling crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

mTOR activation promotes plasma cell differentiation and bypasses XBP-1 for immunoglobulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Spatial coupling of mTOR and autophagy augments secretory phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-016-0246-9

Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses

21 January 2018

1 reference

12 December 2020

Different assembly species of IgM are directed to distinct degradation sites along the secretory pathway.

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12 December 2020

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

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12 December 2020

Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: evidence that retrotranslocation and degradation are coupled events

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12 December 2020

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

1 reference

12 December 2020

Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling

1 reference

12 December 2020

10.1007/S10875-016-0246-9

Identifiers

DOI

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Dimensions Publication ID

6 September 2017

1029973445

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