Therapeutic targeting of CD70 and CD27. (Q38749841)

6 September 2017

title

Therapeutic targeting of CD70 and CD27. (English)

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6 September 2017

1

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6 September 2017

language of work or name

English

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publication date

25 February 2016

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Expert Opinion on Therapeutic Targets

6 September 2017

published in

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6 September 2017

volume

20

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6 September 2017

issue

8

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6 September 2017

page(s)

959-973

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The molecular architecture of the TNF superfamily

6 September 2017

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Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway

21 January 2018

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Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

21 January 2018

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Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains

21 January 2018

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Identification and characterization of a new member of the TNF family that induces apoptosis

21 January 2018

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HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity

21 January 2018

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Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine.

21 January 2018

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Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo.

21 January 2018

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The Fas-FADD death domain complex structure unravels signalling by receptor clustering

21 January 2018

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The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

21 January 2018

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Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation

21 January 2018

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An improved understanding of TNFL/TNFR interactions using structure-based classifications

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Restoration of membrane TNF-like activity by cell surface targeting and matrix metalloproteinase-mediated processing of a TNF prodrug

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Principles of antibody-mediated TNF receptor activation

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Apo2L/TRAIL and the death receptor 5 agonist antibody AMG 655 cooperate to promote receptor clustering and antitumor activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The kinase TNIK is an essential activator of Wnt target genes

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Murine Siva-1 and Siva-2, alternate splice forms of the mouse Siva gene, both bind to CD27 but differentially transduce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Siva-1 promotes K-48 polyubiquitination of TRAF2 and inhibits TCR-mediated activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Signalling via CD70, a member of the TNF family, regulates T cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Aberrant expression and reverse signalling of CD70 on malignant B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Endoplasmic Reticulum Stress-Mediated Apoptosis of EBV-Transformed B Cells by Cross-Linking of CD70 Is Dependent upon Generation of Reactive Oxygen Species and Activation of p38 MAPK and JNK Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Evidence that human CD8+CD45RA+CD27- cells are induced by antigen and evolve through extensive rounds of division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27-CD70 interactions regulate B-cell activation by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The Pim Kinase Pathway Contributes to Survival Signaling in Primed CD8+ T Cells upon CD27 Costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27-CD70 interactions sensitise naive CD4+ T cells for IL-12-induced Th1 cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 instructs CD4+ T cells to provide help for the memory CD8+ T cell response after protein immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70-CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human γδ peripheral blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Role of CD27/CD70 pathway of activation in immunity and tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Elimination of chronic viral infection by blocking CD27 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 is required for generation and long-term maintenance of T cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70 deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to lymphocytic choriomeningitis virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8+ T cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Continuous CD27 triggering in vivo strongly reduces NK cell numbers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70-driven chronic immune activation is protective against atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Eosinophil differentiation in the bone marrow is inhibited by T cell-derived IFN-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Mesenchymal stem cells are mobilized from the bone marrow during inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Expression of costimulatory ligand CD70 on steady-state dendritic cells breaks CD8+ T cell tolerance and permits effective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Chronic CD70-driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL-Fas interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Expression of the immune regulation antigen CD70 in osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody–drug conjugate SGN-75

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Increased CD70 expression is associated with clinical resistance to cisplatin-based chemotherapy and poor survival in advanced ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Expression of CD70 in nasal natural killer/T cell lymphoma cell lines and patients; its role for cell proliferation through binding to soluble CD27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70: a new tumor specific biomarker for renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Identification of CD70 as a diagnostic biomarker for clear cell renal cell carcinoma by gene expression profiling, real-time RT-PCR and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Immune stimulatory effects of CD70 override CD70-mediated immune cell apoptosis in rodent glioma models and confer long-lasting antiglioma immunity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The expression of CD70 and CD80 by gene-modified tumor cells induces an antitumor response depending on the MHC status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Anti-tumor immunity elicited by a recombinant vaccinia virus expressing CD70 (CD27L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Glioblastomas induce T-lymphocyte death by two distinct pathways involving gangliosides and CD70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The CD27 membrane receptor, a lymphocyte-specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

pVHL/HIF-regulated CD70 expression is associated with infiltration of CD27+ lymphocytes and increased serum levels of soluble CD27 in clear cell renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Control of Established Melanoma by CD27 Stimulation Is Associated With Enhanced Effector Function and Persistence, and Reduced PD-1 Expression of Tumor Infiltrating CD8+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Potent anticarcinoma activity of the humanized anti-CD70 antibody h1F6 conjugated to the tubulin inhibitor auristatin via an uncleavable linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Phase I dose-escalation study of SGN-75 in patients with CD70-positive relapsed/refractory non-Hodgkin lymphoma or metastatic renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Anti-CD27 Antibody Potentiates Antitumor Effect of Dendritic Cell-Based Vaccine in Prostate Cancer-Bearing Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Interaction with FcγRIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Increased prevalence of activated CD70+CD4+ T cells in the periphery of patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

T-cell regulation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Blocking of CD27-CD70 pathway by anti-CD70 antibody ameliorates joint disease in murine collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4(+) FoxP3(+) regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

The TNF family in T cell differentiation and function--unanswered questions and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

GITR+ regulatory T cells in the treatment of autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

Solution NMR Investigation of the CD95/FADD Homotypic Death Domain Complex Suggests Lack of Engagement of the CD95 C Terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1158812

10.1517/14728222.2016.1158812

21 January 2018

Identifiers

DOI

1 reference

6 September 2017

1 reference