53BP1 fosters fidelity of homology-directed DNA repair (Q38761656)

6 September 2017

title

53BP1 fosters fidelity of homology-directed DNA repair (English)

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6 September 2017

5

Jiri Lukas

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Kumar Somyajit

object named as

Kumar Somyajit

2

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Matthias Altmeyer

object named as

Matthias Altmeyer

3

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Claudia Lukas

object named as

Claudia Lukas

6

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author name string

Fena Ochs

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6 September 2017

Maj-Britt Rask

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6 September 2017

publication date

27 June 2016

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Nature Structural & Molecular Biology

6 September 2017

published in

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6 September 2017

volume

23

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6 September 2017

issue

8

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6 September 2017

page(s)

714-721

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The DNA-damage response in human biology and disease

6 September 2017

cites work

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Repair Pathway Choices and Consequences at the Double-Strand Break

21 January 2018

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Playing the end game: DNA double-strand break repair pathway choice

21 January 2018

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Sources of DNA double-strand breaks and models of recombinational DNA repair

21 January 2018

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End-joining, translocations and cancer

21 January 2018

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End resection at double-strand breaks: mechanism and regulation

21 January 2018

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Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins

21 January 2018

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Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

21 January 2018

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More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

21 January 2018

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Push back to respond better: regulatory inhibition of the DNA double-strand break response

21 January 2018

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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

21 January 2018

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 January 2018

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53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

21 January 2018

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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

21 January 2018

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A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice

21 January 2018

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RIF1 counteracts BRCA1-mediated end resection during DNA repair

21 January 2018

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PTIP associates with Artemis to dictate DNA repair pathway choice

21 January 2018

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REV7 counteracts DNA double-strand break resection and affects PARP inhibition

21 January 2018

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53BP1 regulates DSB repair using Rif1 to control 5' end resection

21 January 2018

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53BP1: pro choice in DNA repair

21 January 2018

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To spread or not to spread--chromatin modifications in response to DNA damage

21 January 2018

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TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

21 January 2018

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Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining

21 January 2018

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ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

21 January 2018

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Human CtIP promotes DNA end resection

21 January 2018

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Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics

21 January 2018

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ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair

21 January 2018

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Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

21 January 2018

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

21 January 2018

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A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency

21 January 2018

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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

21 January 2018

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Opposing roles for 53BP1 during homologous recombination.

21 January 2018

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RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1

21 January 2018

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Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair

21 January 2018

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BRCA1 accelerates CtIP-mediated DNA-end resection

21 January 2018

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Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement

21 January 2018

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Targeting the DNA Damage Response in Cancer

21 January 2018

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Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

21 January 2018

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Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 January 2018

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The 12p13.33/RAD52 locus and genetic susceptibility to squamous cell cancers of upper aerodigestive tract

21 January 2018

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Association of a functional RAD52 genetic variant locating in a miRNA binding site with risk of HBV-related hepatocellular carcinoma

21 January 2018

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An oncogene-induced DNA damage model for cancer development

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NSMB.3251

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6 September 2017

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