The current progress in understanding the molecular functions and mechanisms of visfatin in osteoarthritis (Q38770891)

6 September 2017

The current progress in understanding the molecular functions and mechanisms of visfatin in osteoarthritis (English)

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6 September 2017

Lele Liao

1

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PubMed ID

26969394

6 September 2017

Yiyue Chen

series ordinal

2

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PubMed ID

26969394

6 September 2017

Wanchun Wang

series ordinal

3

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6 September 2017

11 March 2016

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Journal of Bone and Mineral Metabolism

6 September 2017

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6 September 2017

34

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6 September 2017

485-490

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6 September 2017

5

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https://scigraph.springernature.com/pub.10.1007/s00774-016-0743-1

6 September 2017

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cites work

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Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice

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The effect of body weight on progression of knee osteoarthritis is dependent on alignment

21 January 2018

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The Role of Knee Alignment in Disease Progression and Functional Decline in Knee Osteoarthritis

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Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women?

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Obesity and weight loss in the treatment and prevention of osteoarthritis

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Evidence for a key role of leptin in osteoarthritis

21 January 2018

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Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis.

21 January 2018

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Association between adiponectin and cartilage degradation in human osteoarthritis.

21 January 2018

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Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

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Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

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The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

21 January 2018

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Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

21 January 2018

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Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.

21 January 2018

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RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

21 January 2018

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Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta-analysis and systemic review

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Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

21 January 2018

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Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

21 January 2018

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Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis.

21 January 2018

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Visfatin, an adipocytokine with proinflammatory and immunomodulating properties.

21 January 2018

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The effects of adipokines on cartilage and meniscus catabolism

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The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype.

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Sp1 and Sp3 transcription factors mediate interleukin-1 beta down-regulation of human type II collagen gene expression in articular chondrocytes.

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Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding

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Proinflammatory cytokines, prostaglandins, and the chondrocyte: mechanisms of intracellular activation

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Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics

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The eicosanoids and their biochemical mechanisms of action

21 January 2018

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The Role of Arachidonic Acid Oxygenation Products in Pain and Inflammation

21 January 2018

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Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: possible influence on osteoarthritis.

21 January 2018

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Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.

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New treatments for osteoarthritis

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Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain

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NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis

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Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD(+)-SIRT axis in articular chondrocytes is involved in osteoarthritis

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Emerging regulators of the inflammatory process in osteoarthritis

21 January 2018

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Towards elucidating the role of SirT1 in osteoarthritis.

21 January 2018

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Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase

21 January 2018

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SIRT1 regulation of apoptosis of human chondrocytes

21 January 2018

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Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

21 January 2018

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Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling

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Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway

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Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes

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Lipid Profiles and Serum Visfatin Concentrations in Patients with Type II Diabetes in Comparison with Healthy Controls.

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12 December 2020

Interleukin-1beta induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor-stimulated gene 6 in human osteoarthritic chondrocytes in vitro

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12 December 2020

Increased synovial fluid visfatin is positively linked to cartilage degradation biomarkers in osteoarthritis

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12 December 2020

Induction of the chemokine IL-8/Kc by the articular cartilage: possible influence on osteoarthritis

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12 December 2020

Obesity and osteoarthritis: is leptin the link?

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12 December 2020

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions

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12 December 2020

Body weight, body mass index, and incident symptomatic osteoarthritis of the hand, hip, and knee.

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12 December 2020

Increased serum concentrations of visfatin and its production by different joint tissues in patients with osteoarthritis

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12 December 2020

Physiological and pathophysiological roles of NAMPT and NAD metabolism

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12 December 2020

10.1007/S00774-016-0743-1

Identifiers

DOI

1 reference

6 September 2017

1 reference

PubMed ID

26969394