An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors (Q38803301)

6 September 2017

title

An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors (English)

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6 September 2017

Frederique M Poulet

1

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6 September 2017

Jayanthi J Wolf

series ordinal

2

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6 September 2017

Danuta J Herzyk

series ordinal

3

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6 September 2017

Joseph J DeGeorge

series ordinal

4

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6 September 2017

publication date

7 April 2016

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Birth Defects Research Part B: Developmental and Reproductive Toxicology

6 September 2017

published in

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6 September 2017

volume

107

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6 September 2017

issue

2

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6 September 2017

page(s)

108-119

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Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

6 September 2017

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SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

21 January 2018

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

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Interleukin-10: a pleiotropic regulator in pregnancy

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The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance.

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The placenta, transfer of immunoglobulins, and safety assessment of biopharmaceuticals in pregnancy.

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Immune regulation of cancer

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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Mechanisms of T cell tolerance towards the allogeneic fetus

21 January 2018

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Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus

21 January 2018

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A critical review of the role of the major histocompatibility complex in fertilization, preimplantation development and feto-maternal interactions

21 January 2018

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The PD-1 pathway in tolerance and autoimmunity

21 January 2018

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

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Comparative developmental anatomy of the murine and human definitive placentae.

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The B7 family revisited

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PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

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A critical role for the programmed death ligand 1 in fetomaternal tolerance

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Maternal acceptance of the fetus: true human tolerance

21 January 2018

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Complement and pregnancy: new insights into the immunobiology of the fetomaternal relationship

21 January 2018

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Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

21 January 2018

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Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

21 January 2018

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Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy

21 January 2018

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Tissue expression of PD-L1 mediates peripheral T cell tolerance.

21 January 2018

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PD-1 and its ligands in tolerance and immunity

21 January 2018

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Placental HLA-G protein expression in vivo: where and what for?

21 January 2018

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Considerations in assessing the developmental and reproductive toxicity potential of biopharmaceuticals

21 January 2018

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Developmental toxicity testing of biopharmaceuticals in nonhuman primates: previous experience and future directions

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

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IDO expression on decidual and peripheral blood dendritic cells and monocytes/macrophages after treatment with CTLA-4 or interferon-gamma increase in normal pregnancy but decrease in spontaneous abortion

21 January 2018

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

21 January 2018

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Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice

21 January 2018

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Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

21 January 2018

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Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.

21 January 2018

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PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

21 January 2018

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Effector memory T cells, early metastasis, and survival in colorectal cancer

21 January 2018

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CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

21 January 2018

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Review: Fetal antigens--identity, origins, and influences on the maternal immune system

21 January 2018

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An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies

21 January 2018

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Major histocompatibility complex I mediates immunological tolerance of the trophoblast during pregnancy and may mediate rejection during parturition

21 January 2018

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PD-1 signaling in primary T cells

21 January 2018

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NK cells and human pregnancy--an inflammatory view.

21 January 2018

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21 January 2018

The B7-CD28 superfamily

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https://api.crossref.org/works/10.1002%2FBDRB.21176

PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta

21 January 2018

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Structure and chromosomal localization of the human PD-1 gene (PDCD1)

21 January 2018

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Maternal PD-1 regulates accumulation of fetal antigen-specific CD8+ T cells in pregnancy

21 January 2018

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Major histocompatibility complex (MHC)-mediated immune regulation of decidual leukocytes at the fetal-maternal interface.

21 January 2018

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

21 January 2018

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Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma

21 January 2018

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

21 January 2018

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Activation-induced expression of human programmed death-1 gene in T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

The enhanced pre- and postnatal study for nonhuman primates: update and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

A critical role for murine complement regulator crry in fetomaternal tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRB.21176

21 January 2018

Identifiers

DOI

10.1002/BDRB.21176

1 reference

6 September 2017

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